Detalhe da pesquisa
1.
Synthesis and biological evaluation of biaryl alkyl ethers as inhibitors of IDO1.
Bioorg Med Chem Lett
; 88: 129280, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37054759
2.
The discovery of BMS-737 as a potent, CYP17 lyase-selective inhibitor for the treatment of castration-resistant prostate cancer.
Bioorg Med Chem Lett
; 75: 128951, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36031020
3.
Structural basis for CARM1 inhibition by indole and pyrazole inhibitors.
Biochem J
; 436(2): 331-9, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21410432
4.
An electrophoretic mobility shift assay for the identification and kinetic analysis of acetyl transferase inhibitors.
Anal Biochem
; 402(1): 65-8, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20338149
5.
Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies.
Bioorg Med Chem Lett
; 19(17): 5063-6, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19632837
6.
Optimization of pyrazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1).
Bioorg Med Chem Lett
; 19(11): 2924-7, 2009 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19419866
7.
Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1).
Bioorg Med Chem Lett
; 18(15): 4438-41, 2008 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18619839
8.
CRLX101, a Nanoparticle-Drug Conjugate Containing Camptothecin, Improves Rectal Cancer Chemoradiotherapy by Inhibiting DNA Repair and HIF1α.
Cancer Res
; 77(1): 112-122, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27784746
9.
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit.
Sci Rep
; 7(1): 13853, 2017 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29062039
10.
Preclinical Efficacy of Bevacizumab with CRLX101, an Investigational Nanoparticle-Drug Conjugate, in Treatment of Metastatic Triple-Negative Breast Cancer.
Cancer Res
; 76(15): 4493-503, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27325647
11.
Dissecting Therapeutic Resistance to ERK Inhibition.
Mol Cancer Ther
; 15(4): 548-59, 2016 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26832798
12.
Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer.
ACS Med Chem Lett
; 7(1): 40-5, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26819663
13.
Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.
Cancer Discov
; 3(7): 742-50, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23614898