Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Identification of constrained sequence elements across 239 primate genomes.

Kuderna, Lukas F K; Ulirsch, Jacob C; Rashid, Sabrina; Ameen, Mohamed; Sundaram, Laksshman; Hickey, Glenn; Cox, Anthony J; Gao, Hong; Kumar, Arvind; Aguet, Francois; Christmas, Matthew J; Clawson, Hiram; Haeussler, Maximilian; Janiak, Mareike C; Kuhlwilm, Martin; Orkin, Joseph D; Bataillon, Thomas; Manu, Shivakumara; Valenzuela, Alejandro; Bergman, Juraj; Rouselle, Marjolaine; Silva, Felipe Ennes; Agueda, Lidia; Blanc, Julie; Gut, Marta; de Vries, Dorien; Goodhead, Ian; Harris, R Alan; Raveendran, Muthuswamy; Jensen, Axel; Chuma, Idriss S; Horvath, Julie E; Hvilsom, Christina; Juan, David; Frandsen, Peter; Schraiber, Joshua G; de Melo, Fabiano R; Bertuol, Fabrício; Byrne, Hazel; Sampaio, Iracilda; Farias, Izeni; Valsecchi, João; Messias, Malu; da Silva, Maria N F; Trivedi, Mihir; Rossi, Rogerio; Hrbek, Tomas; Andriaholinirina, Nicole; Rabarivola, Clément J; Zaramody, Alphonse.

Nature ; 625(7996): 735-742, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38030727

2.

Complex Evolutionary History With Extensive Ancestral Gene Flow in an African Primate Radiation.

Jensen, Axel; Swift, Frances; de Vries, Dorien; Beck, Robin M D; Kuderna, Lukas F K; Knauf, Sascha; Chuma, Idrissa S; Keyyu, Julius D; Kitchener, Andrew C; Farh, Kyle; Rogers, Jeffrey; Marques-Bonet, Tomas; Detwiler, Kate M; Roos, Christian; Guschanski, Katerina.

Mol Biol Evol ; 40(12)2023 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-37987553

3.

Ten Years of Improving Acute Stroke Management in a Metropolitan Area: A Population-Based Quantification of Quality Indicators.

Alegiani, Anna; Rosenkranz, Michael; Schmitz, Leonie; Lezius, Susanne; Seidel, Günter; Heßelmann, Volker; Töpper, Rudolf; Terborg, Christoph; Urban, Peter P; Brüning, Roland; Höltje, Jan; Lienau, Florian; Arning, Christian; Marquardt, Lars; Müller-Jensen, Axel; Röther, Joachim; Eckert, Bernd; Zapf, Antonia; Fiehler, Jens; Thomalla, Götz; Gerloff, Christian.

Eur Neurol ; 85(1): 39-49, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-34818228

4.

Whole genome sequencing reveals high differentiation, low levels of genetic diversity and short runs of homozygosity among Swedish wels catfish.

Jensen, Axel; Lillie, Mette; Bergström, Kristofer; Larsson, Per; Höglund, Jacob.

Heredity (Edinb) ; 127(1): 79-91, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-33963302

5.

Screening for TB by sputum culture in high-risk groups in Copenhagen, Denmark: a novel and promising approach.

Jensen, Sidse Graff; Olsen, Nete Wrona; Seersholm, Niels; Lillebaek, Troels; Wilcke, Torgny; Pedersen, Mathias Klok; Kok-Jensen, Axel.

Thorax ; 70(10): 979-83, 2015 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-26156525

6.

Comparative genomic analyses provide new insights into evolutionary history and conservation genomics of gorillas.

van der Valk, Tom; Jensen, Axel; Caillaud, Damien; Guschanski, Katerina.

BMC Ecol Evol ; 24(1): 14, 2024 Jan 26.

Artigo em Inglês | MEDLINE | ID: mdl-38273244

7.

A global catalog of whole-genome diversity from 233 primate species.

Kuderna, Lukas F K; Gao, Hong; Janiak, Mareike C; Kuhlwilm, Martin; Orkin, Joseph D; Bataillon, Thomas; Manu, Shivakumara; Valenzuela, Alejandro; Bergman, Juraj; Rousselle, Marjolaine; Silva, Felipe Ennes; Agueda, Lidia; Blanc, Julie; Gut, Marta; de Vries, Dorien; Goodhead, Ian; Harris, R Alan; Raveendran, Muthuswamy; Jensen, Axel; Chuma, Idrissa S; Horvath, Julie E; Hvilsom, Christina; Juan, David; Frandsen, Peter; Schraiber, Joshua G; de Melo, Fabiano R; Bertuol, Fabrício; Byrne, Hazel; Sampaio, Iracilda; Farias, Izeni; Valsecchi, João; Messias, Malu; da Silva, Maria N F; Trivedi, Mihir; Rossi, Rogerio; Hrbek, Tomas; Andriaholinirina, Nicole; Rabarivola, Clément J; Zaramody, Alphonse; Jolly, Clifford J; Phillips-Conroy, Jane; Wilkerson, Gregory; Abee, Christian; Simmons, Joe H; Fernandez-Duque, Eduardo; Kanthaswamy, Sree; Shiferaw, Fekadu; Wu, Dongdong; Zhou, Long; Shao, Yong.

Science ; 380(6648): 906-913, 2023 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-37262161

8.

The landscape of tolerated genetic variation in humans and primates.

Gao, Hong; Hamp, Tobias; Ede, Jeffrey; Schraiber, Joshua G; McRae, Jeremy; Singer-Berk, Moriel; Yang, Yanshen; Dietrich, Anastasia S D; Fiziev, Petko P; Kuderna, Lukas F K; Sundaram, Laksshman; Wu, Yibing; Adhikari, Aashish; Field, Yair; Chen, Chen; Batzoglou, Serafim; Aguet, Francois; Lemire, Gabrielle; Reimers, Rebecca; Balick, Daniel; Janiak, Mareike C; Kuhlwilm, Martin; Orkin, Joseph D; Manu, Shivakumara; Valenzuela, Alejandro; Bergman, Juraj; Rousselle, Marjolaine; Silva, Felipe Ennes; Agueda, Lidia; Blanc, Julie; Gut, Marta; de Vries, Dorien; Goodhead, Ian; Harris, R Alan; Raveendran, Muthuswamy; Jensen, Axel; Chuma, Idriss S; Horvath, Julie E; Hvilsom, Christina; Juan, David; Frandsen, Peter; de Melo, Fabiano R; Bertuol, Fabrício; Byrne, Hazel; Sampaio, Iracilda; Farias, Izeni; do Amaral, João Valsecchi; Messias, Mariluce; da Silva, Maria N F; Trivedi, Mihir.

Science ; 380(6648): eabn8153, 2023 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-37262156

9.

The landscape of tolerated genetic variation in humans and primates.

Gao, Hong; Hamp, Tobias; Ede, Jeffrey; Schraiber, Joshua G; McRae, Jeremy; Singer-Berk, Moriel; Yang, Yanshen; Dietrich, Anastasia; Fiziev, Petko; Kuderna, Lukas; Sundaram, Laksshman; Wu, Yibing; Adhikari, Aashish; Field, Yair; Chen, Chen; Batzoglou, Serafim; Aguet, Francois; Lemire, Gabrielle; Reimers, Rebecca; Balick, Daniel; Janiak, Mareike C; Kuhlwilm, Martin; Orkin, Joseph D; Manu, Shivakumara; Valenzuela, Alejandro; Bergman, Juraj; Rouselle, Marjolaine; Silva, Felipe Ennes; Agueda, Lidia; Blanc, Julie; Gut, Marta; de Vries, Dorien; Goodhead, Ian; Harris, R Alan; Raveendran, Muthuswamy; Jensen, Axel; Chuma, Idriss S; Horvath, Julie; Hvilsom, Christina; Juan, David; Frandsen, Peter; de Melo, Fabiano R; Bertuol, Fabricio; Byrne, Hazel; Sampaio, Iracilda; Farias, Izeni; do Amaral, João Valsecchi; Messias, Mariluce; da Silva, Maria N F; Trivedi, Mihir.

bioRxiv ; 2023 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-37205491

10.

Migrant tuberculosis: the extent of transmission in a low burden country.

Kamper-Jørgensen, Zaza; Andersen, Aase Bengaard; Kok-Jensen, Axel; Kamper-Jørgensen, Mads; Bygbjerg, Ib Christian; Andersen, Peter Henrik; Thomsen, Vibeke Ostergaard; Lillebaek, Troels.

BMC Infect Dis ; 12: 60, 2012 Mar 18.

Artigo em Inglês | MEDLINE | ID: mdl-22423983

11.

New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease.

Kleymann, Gerald; Fischer, Rüdiger; Betz, Ulrich A K; Hendrix, Martin; Bender, Wolfgang; Schneider, Udo; Handke, Gabriele; Eckenberg, Peter; Hewlett, Guy; Pevzner, Veniamin; Baumeister, Judith; Weber, Olaf; Henninger, Kerstin; Keldenich, Jörg; Jensen, Axel; Kolb, Jörg; Bach, Ute; Popp, Andreas; Mäben, Jutta; Frappa, Isabelle; Haebich, Dieter; Lockhoff, Oswald; Rübsamen-Waigmann, Helga.

Nat Med ; 8(4): 392-8, 2002 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-11927946

12.

Clinical outcome and imaging follow-up in acute stroke patients with normal perfusion CT and normal CT angiography.

Eckert, Bernd; Küsel, Tobias; Leppien, Andreas; Michels, Peter; Müller-Jensen, Axel; Fiehler, Jens.

Neuroradiology ; 53(2): 79-88, 2011 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-20422406

13.

Endovascular treatment in proximal and intracranial carotid occlusion 9 hours after symptom onset.

Jakubowska, Malgorzata M; Michels, Peter; Müller-Jensen, Axel; Leppien, Andreas; Eckert, Bernd.

Neuroradiology ; 50(7): 599-604, 2008 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-18443776

14.

Bacillarity at autopsy in pulmonary tuberculosis. Mycobacterium tuberculosis is often disseminated.

Lillebaek, Troels; Kok-Jensen, Axel; Viskum, Kaj.

APMIS ; 110(9): 625-9, 2002 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-12529015

15.

Characteristics of non-clustered tuberculosis in a low burden country.

Kamper-Jørgensen, Zaza; Andersen, Aase Bengaard; Kok-Jensen, Axel; Bygbjerg, Ib Christian; Thomsen, Vibeke Ostergaard; Lillebaek, Troels.

Tuberculosis (Edinb) ; 92(3): 226-31, 2012 May.

Artigo em Inglês | MEDLINE | ID: mdl-22406154

16.

[Tuberculosis among Danish men]. / Tuberkulose blandt danske maend.

Kok-Jensen, Axel.

Ugeskr Laeger ; 167(4): 373, 2005 Jan 24.

Artigo em Dinamarquês | MEDLINE | ID: mdl-15719558

17.

[The fight against tuberculosis in Denmark until 2050]. / Tuberkulosebekæmpelsen i Danmark frem til 2050.

Kok-Jensen, Axel.

Ugeskr Laeger ; 174(44): 2694, 2012 Oct 29.

Artigo em Dinamarquês | MEDLINE | ID: mdl-23121904

18.

[Can tuberculosis be eliminated in Denmark before 2040?]. / Kan tuberkulose elimineres i Danmark før 2040?

Kok-Jensen, Axel.

Ugeskr Laeger ; 173(12): 871, 2011 Mar 21.

Artigo em Dinamarquês | MEDLINE | ID: mdl-21419053

19.

Prospective evaluation of a whole-blood test using Mycobacterium tuberculosis-specific antigens ESAT-6 and CFP-10 for diagnosis of active tuberculosis.

Ravn, Pernille; Munk, Martin E; Andersen, Ase B; Lundgren, Bettina; Lundgren, Jens D; Nielsen, Lars N; Kok-Jensen, Axel; Andersen, Peter; Weldingh, Karin.

Clin Diagn Lab Immunol ; 12(4): 491-6, 2005 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-15817755

20.

Mannose-binding lectin polymorphisms in clinical tuberculosis.

Søborg, Christian; Madsen, Hans O; Andersen, Ase B; Lillebaek, Troels; Kok-Jensen, Axel; Garred, Peter.

J Infect Dis ; 188(5): 777-82, 2003 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-12934195

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Identification of constrained sequence elements across 239 primate genomes.

Complex Evolutionary History With Extensive Ancestral Gene Flow in an African Primate Radiation.

Ten Years of Improving Acute Stroke Management in a Metropolitan Area: A Population-Based Quantification of Quality Indicators.

Whole genome sequencing reveals high differentiation, low levels of genetic diversity and short runs of homozygosity among Swedish wels catfish.

Screening for TB by sputum culture in high-risk groups in Copenhagen, Denmark: a novel and promising approach.

Comparative genomic analyses provide new insights into evolutionary history and conservation genomics of gorillas.

A global catalog of whole-genome diversity from 233 primate species.

The landscape of tolerated genetic variation in humans and primates.

The landscape of tolerated genetic variation in humans and primates.

Migrant tuberculosis: the extent of transmission in a low burden country.

New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease.

Clinical outcome and imaging follow-up in acute stroke patients with normal perfusion CT and normal CT angiography.

Endovascular treatment in proximal and intracranial carotid occlusion 9 hours after symptom onset.

Bacillarity at autopsy in pulmonary tuberculosis. Mycobacterium tuberculosis is often disseminated.

Characteristics of non-clustered tuberculosis in a low burden country.

[Tuberculosis among Danish men]. / Tuberkulose blandt danske maend.

[The fight against tuberculosis in Denmark until 2050]. / Tuberkulosebekæmpelsen i Danmark frem til 2050.

[Can tuberculosis be eliminated in Denmark before 2040?]. / Kan tuberkulose elimineres i Danmark før 2040?

Prospective evaluation of a whole-blood test using Mycobacterium tuberculosis-specific antigens ESAT-6 and CFP-10 for diagnosis of active tuberculosis.

Mannose-binding lectin polymorphisms in clinical tuberculosis.