Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Anoctamin 8 tethers endoplasmic reticulum and plasma membrane for assembly of Ca²⁺ signaling complexes at the ER/PM compartment.

Jha, Archana; Chung, Woo Young; Vachel, Laura; Maleth, Jozsef; Lake, Sarah; Zhang, Guofeng; Ahuja, Malini; Muallem, Shmuel.

EMBO J ; 38(12)2019 06 17.

Artigo em Inglês | MEDLINE | ID: mdl-31061173

2.

Lipids at membrane contact sites: cell signaling and ion transport.

Muallem, Shmuel; Chung, Woo Young; Jha, Archana; Ahuja, Malini.

EMBO Rep ; 18(11): 1893-1904, 2017 11.

Artigo em Inglês | MEDLINE | ID: mdl-29030479

3.

Convergent regulation of the lysosomal two-pore channel-2 by Mg²âº, NAADP, PI(3,5)P2 and multiple protein kinases.

Jha, Archana; Ahuja, Malini; Patel, Sandip; Brailoiu, Eugen; Muallem, Shmuel.

EMBO J ; 33(5): 501-11, 2014 Mar 03.

Artigo em Inglês | MEDLINE | ID: mdl-24502975

4.

Fusion of lysosomes with secretory organelles leads to uncontrolled exocytosis in the lysosomal storage disease mucolipidosis type IV.

Park, Soonhong; Ahuja, Malini; Kim, Min Seuk; Brailoiu, G Cristina; Jha, Archana; Zeng, Mei; Baydyuk, Maryna; Wu, Ling-Gang; Wassif, Christopher A; Porter, Forbes D; Zerfas, Patricia M; Eckhaus, Michael A; Brailoiu, Eugen; Shin, Dong Min; Muallem, Shmuel.

EMBO Rep ; 17(2): 266-78, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26682800

5.

STIM-TRP Pathways and Microdomain Organization: Ca²⁺ Influx Channels: The Orai-STIM1-TRPC Complexes.

Bodnar, Dora; Chung, Woo Young; Yang, Dongki; Hong, Jeong Hee; Jha, Archana; Muallem, Shmuel.

Adv Exp Med Biol ; 993: 139-157, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28900913

6.

The TRPCs-STIM1-Orai interaction.

Choi, Seok; Maleth, Jozsef; Jha, Archana; Lee, Kyu Pil; Kim, Min Seuk; So, Insuk; Ahuja, Malini; Muallem, Shmuel.

Handb Exp Pharmacol ; 223: 1035-54, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-24961979

7.

OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage.

Tsvilovskyy, Volodymyr; Ottenheijm, Roger; Kriebs, Ulrich; Schütz, Aline; Diakopoulos, Kalliope Nina; Jha, Archana; Bildl, Wolfgang; Wirth, Angela; Böck, Julia; Jaslan, Dawid; Ferro, Irene; Taberner, Francisco J; Kalinina, Olga; Hildebrand, Staffan; Wissenbach, Ulrich; Weissgerber, Petra; Vogt, Dominik; Eberhagen, Carola; Mannebach, Stefanie; Berlin, Michael; Kuryshev, Vladimir; Schumacher, Dagmar; Philippaert, Koenraad; Camacho-Londoño, Juan E; Mathar, Ilka; Dieterich, Christoph; Klugbauer, Norbert; Biel, Martin; Wahl-Schott, Christian; Lipp, Peter; Flockerzi, Veit; Zischka, Hans; Algül, Hana; Lechner, Stefan G; Lesina, Marina; Grimm, Christian; Fakler, Bernd; Schulte, Uwe; Muallem, Shmuel; Freichel, Marc.

J Clin Invest ; 134(7)2024 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-38557489

8.

The energetic consequences of loop 9 gating motions in acetylcholine receptor-channels.

Jha, Archana; Gupta, Shaweta; Zucker, Shoshanna N; Auerbach, Anthony.

J Physiol ; 590(1): 119-29, 2012 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-22025664

9.

Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels.

Yamaguchi, Soichiro; Jha, Archana; Li, Qin; Soyombo, Abigail A; Dickinson, George D; Churamani, Dev; Brailoiu, Eugen; Patel, Sandip; Muallem, Shmuel.

J Biol Chem ; 286(26): 22934-42, 2011 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-21540176

10.

Cholecystokinin facilitates glutamate release by increasing the number of readily releasable vesicles and releasing probability.

Deng, Pan-Yue; Xiao, Zhaoyang; Jha, Archana; Ramonet, David; Matsui, Toshimitsu; Leitges, Michael; Shin, Hee-Sup; Porter, James E; Geiger, Jonathan D; Lei, Saobo.

J Neurosci ; 30(15): 5136-48, 2010 Apr 14.

Artigo em Inglês | MEDLINE | ID: mdl-20392936

11.

Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.

Rühl, Philipp; Rosato, Anna Scotto; Urban, Nicole; Gerndt, Susanne; Tang, Rachel; Abrahamian, Carla; Leser, Charlotte; Sheng, Jiansong; Jha, Archana; Vollmer, Günter; Schaefer, Michael; Bracher, Franz; Grimm, Christian.

Sci Rep ; 11(1): 8313, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33859333

12.

GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis.

Goodwin, Jonathan M; Walkup, Ward G; Hooper, Kirsty; Li, Taoyingnan; Kishi-Itakura, Chieko; Ng, Aylwin; Lehmberg, Timothy; Jha, Archana; Kommineni, Sravya; Fletcher, Katherine; Garcia-Fortanet, Jorge; Fan, Yaya; Tang, Qing; Wei, Menghao; Agrawal, Asmita; Budhe, Sagar R; Rouduri, Sreekanth R; Baird, Dan; Saunders, Jeff; Kiselar, Janna; Chance, Mark R; Ballabio, Andrea; Appleton, Brent A; Brumell, John H; Florey, Oliver; Murphy, Leon O.

Sci Adv ; 7(40): eabj2485, 2021 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-34597140

13.

Acetylcholine receptor channels activated by a single agonist molecule.

Jha, Archana; Auerbach, Anthony.

Biophys J ; 98(9): 1840-6, 2010 May 19.

Artigo em Inglês | MEDLINE | ID: mdl-20441747

14.

Energy and structure of the M2 helix in acetylcholine receptor-channel gating.

Jha, Archana; Purohit, Prasad; Auerbach, Anthony.

Biophys J ; 96(10): 4075-84, 2009 May 20.

Artigo em Inglês | MEDLINE | ID: mdl-19450479

15.

Mining of Ebola virus entry inhibitors identifies approved drugs as two-pore channel pore blockers.

Penny, Christopher J; Vassileva, Kristin; Jha, Archana; Yuan, Yu; Chee, Xavier; Yates, Elizabeth; Mazzon, Michela; Kilpatrick, Bethan S; Muallem, Shmuel; Marsh, Mark; Rahman, Taufiq; Patel, Sandip.

Biochim Biophys Acta Mol Cell Res ; 1866(7): 1151-1161, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30408544

16.

Acetylcholine receptor gating at extracellular transmembrane domain interface: the cys-loop and M2-M3 linker.

Jha, Archana; Cadugan, David J; Purohit, Prasad; Auerbach, Anthony.

J Gen Physiol ; 130(6): 547-58, 2007 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-18040057

17.

3-Nitropropionic acid-induced depression of spinal reflexes does not involve 5-hydroxytryptaminergic system in contrast to ischemia-induced depression in neonatal rat spinal cord in vitro.

Gupta, Rajesh; Jha, Archana; Deshpande, Shripad B.

Neurosci Lett ; 446(2-3): 93-6, 2008 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-18817848

18.

Opening the Orai1 gates.

Muallem, Shmuel; Jha, Archana.

Sci Signal ; 10(507)2017 11 28.

Artigo em Inglês | MEDLINE | ID: mdl-29184032

19.

Ca²⁺ influx at the ER/PM junctions.

Chung, Woo Young; Jha, Archana; Ahuja, Malini; Muallem, Shmuel.

Cell Calcium ; 63: 29-32, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28262262

20.

Localization of the mouse alpha1A-adrenergic receptor (AR) in the brain: alpha1AAR is expressed in neurons, GABAergic interneurons, and NG2 oligodendrocyte progenitors.

Papay, Robert; Gaivin, Robert; Jha, Archana; McCune, Dan F; McGrath, John C; Rodrigo, Manoj C; Simpson, Paul C; Doze, Van A; Perez, Dianne M.

J Comp Neurol ; 497(2): 209-22, 2006 Jul 10.

Artigo em Inglês | MEDLINE | ID: mdl-16705673

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