Detalhe da pesquisa
1.
Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue.
Int J Mol Sci
; 23(9)2022 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35563647
2.
Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta.
Lab Invest
; 101(12): 1605-1617, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34462532
3.
Synthesis of Fused Indolines by Interrupted Fischer Indolization in a Microfluidic Reactor.
Tetrahedron Lett
; 60(3): 322-326, 2019 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30631216
4.
Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2.
Biochem Biophys Res Commun
; 499(4): 751-757, 2018 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29604274
5.
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair.
Ann Rheum Dis
; 77(5): 760-769, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29436471
6.
C-O bond Formation in a Microfluidic Reactor: High Yield SNAr Substitution of Heteroaryl Chlorides.
Tetrahedron Lett
; 57(19): 2059-2062, 2016 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27152054
7.
Neuroprotective Sirtuin ratio reversed by ApoE4.
Proc Natl Acad Sci U S A
; 110(45): 18303-8, 2013 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24145446
8.
Simultaneous isolation of intact brain cells and cell-specific extracellular vesicles from cryopreserved Alzheimer's disease cortex.
J Neurosci Methods
; 406: 110137, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38626853
9.
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors.
Bioorg Med Chem Lett
; 23(16): 4674-9, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23856050
10.
Pharmacological Inhibition of p-21 Activated Kinase (PAK) Restores Impaired Neurite Outgrowth and Remodeling in a Cellular Model of Down Syndrome.
Neurotox Res
; 41(3): 256-269, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36867391
11.
A therapeutic small molecule lead enhances γ-oscillations and improves cognition/memory in Alzheimer's disease model mice.
bioRxiv
; 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38106006
12.
Distinct Patterns of Gene Expression Changes in the Colon and Striatum of Young Mice Overexpressing Alpha-Synuclein Support Parkinson's Disease as a Multi-System Process.
J Parkinsons Dis
; 13(7): 1127-1147, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37638450
13.
Posiphen as a candidate drug to lower CSF amyloid precursor protein, amyloid-ß peptide and τ levels: target engagement, tolerability and pharmacokinetics in humans.
J Neurol Neurosurg Psychiatry
; 83(9): 894-902, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22791904
14.
Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene diphosphonate.
Elife
; 112022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36017995
15.
Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice.
Commun Med (Lond)
; 2: 112, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36082175
16.
Pharmacological induction of neuroglobin expression.
Pharmacology
; 87(1-2): 81-4, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21228614
17.
Behavioral Deficits and Brain α-Synuclein and Phosphorylated Serine-129 α-Synuclein in Male and Female Mice Overexpressing Human α-Synuclein.
J Alzheimers Dis
; 79(2): 875-893, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33361597
18.
Designing Physical Human-Robot Interaction Interfaces: A Scalable Method for Simulation Based Design.
Front Neurorobot
; 15: 727534, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35250527
19.
Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer's Disease Brain Tissue Reveals Disease-Associated Signatures.
Front Pharmacol
; 12: 766082, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34925024
20.
Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.
Mol Brain
; 14(1): 70, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33875010