Global variability in seawater Mg:Ca and Sr:Ca ratios in the modern ocean.

Seawater Mg:Ca and Sr:Ca ratios are biogeochemical parameters reflecting the Earth-ocean-atmosphere dynamic exchange of elements. The ratios' dependence on the environment and organisms' biology facilitates their application in marine sciences. Here, we present a measured single-laboratory dataset, combined with previous data, to test the assumption of limited seawater Mg:Ca and Sr:Ca variability across marine environments globally. High variability was found in open-ocean upwelling and polar regions, shelves/neritic and river-influenced areas, where seawater Mg:Ca and Sr:Ca ratios range from ∼4.40 to 6.40 mmol:mol and ∼6.95 to 9.80 mmol:mol, respectively. Open-ocean seawater Mg:Ca is semiconservative (∼4.90 to 5.30 mol:mol), while Sr:Ca is more variable and nonconservative (∼7.70 to 8.80 mmol:mol); both ratios are nonconservative in coastal seas. Further, the Ca, Mg, and Sr elemental fluxes are connected to large total alkalinity deviations from International Association for the Physical Sciences of the Oceans (IAPSO) standard values. Because there is significant modern seawater Mg:Ca and Sr:Ca ratios variability across marine environments we cannot absolutely assume that fossil archives using taxa-specific proxies reflect true global seawater chemistry but rather taxa- and process-specific ecosystem variations, reflecting regional conditions. This variability could reconcile secular seawater Mg:Ca and Sr:Ca ratio reconstructions using different taxa and techniques by assuming an error of 1 to 1.50 mol:mol, and 1 to 1.90 mmol:mol, respectively. The modern ratios' variability is similar to the reconstructed rise over 20 Ma (Neogene Period), nurturing the question of seminonconservative behavior of Ca, Mg, and Sr over modern Earth geological history with an overlooked environmental effect.

Macronutrient and carbon supply, uptake and cycling across the Antarctic Peninsula shelf during summer.

The West Antarctic Peninsula shelf is a region of high seasonal primary production which supports a large and productive food web, where macronutrients and inorganic carbon are sourced primarily from intrusions of warm saline Circumpolar Deep Water. We examined the cross-shelf modification of this water mass during mid-summer 2015 to understand the supply of nutrients and carbon to the productive surface ocean, and their subsequent uptake and cycling. We show that nitrate, phosphate, silicic acid and inorganic carbon are progressively enriched in subsurface waters across the shelf, contrary to cross-shelf reductions in heat, salinity and density. We use nutrient stoichiometric and isotopic approaches to invoke remineralization of organic matter, including nitrification below the euphotic surface layer, and dissolution of biogenic silica in deeper waters and potentially shelf sediment porewaters, as the primary drivers of cross-shelf enrichments. Regenerated nitrate and phosphate account for a significant proportion of the total pools of these nutrients in the upper ocean, with implications for the seasonal carbon sink. Understanding nutrient and carbon dynamics in this region now will inform predictions of future biogeochemical changes in the context of substantial variability and ongoing changes in the physical environment.This article is part of the theme issue 'The marine system of the West Antarctic Peninsula: status and strategy for progress in a region of rapid change'.

Impact of sea-ice melt on dimethyl sulfide (sulfoniopropionate) inventories in surface waters of Marguerite Bay, West Antarctic Peninsula.

The Southern Ocean is a hotspot of the climate-relevant organic sulfur compound dimethyl sulfide (DMS). Spatial and temporal variability in DMS concentration is higher than in any other oceanic region, especially in the marginal ice zone. During a one-week expedition across the continental shelf of the West Antarctic Peninsula (WAP), from the shelf break into Marguerite Bay, in January 2015, spatial heterogeneity of DMS and its precursor dimethyl sulfoniopropionate (DMSP) was studied and linked with environmental conditions, including sea-ice melt events. Concentrations of sulfur compounds, particulate organic carbon (POC) and chlorophyll a in the surface waters varied by a factor of 5-6 over the entire transect. DMS and DMSP concentrations were an order of magnitude higher than currently inferred in climatologies for the WAP region. Particulate DMSP concentrations were correlated most strongly with POC and the abundance of haptophyte algae within the phytoplankton community, which, in turn, was linked with sea-ice melt. The strong sea-ice signal in the distribution of DMS(P) implies that DMS(P) production is likely to decrease with ongoing reductions in sea-ice cover along the WAP. This has implications for feedback processes on the region's climate system.This article is part of the theme issue 'The marine system of the West Antarctic Peninsula: status and strategy for progress in a region of rapid change'.

Electrochemical stiffness in lithium-ion batteries.

Although lithium-ion batteries are ubiquitous in portable electronics, increased charge rate and discharge power are required for more demanding applications such as electric vehicles. The high-rate exchange of lithium ions required for more power and faster charging generates significant stresses and strains in the electrodes that ultimately lead to performance degradation. To date, electrochemically induced stresses and strains in battery electrodes have been studied only individually. Here, a new technique is developed to probe the chemomechanical response of electrodes by calculating the electrochemical stiffness via coordinated in situ stress and strain measurements. We show that dramatic changes in electrochemical stiffness occur due to the formation of different graphite-lithium intercalation compounds during cycling. Our analysis reveals that stress scales proportionally with the lithiation/delithiation rate and strain scales proportionally with capacity (and inversely with rate). Electrochemical stiffness measurements provide new insights into the origin of rate-dependent chemomechanical degradation and the evaluation of advanced battery electrodes.

Comparison of cone-beam computed tomography with multislice computed tomography in detection of small osseous condylar defects.

INTRODUCTION: Previous studies have indicated that orthodontic-grade cone-beam computed tomography (CBCT) images are limited when displaying small defects at the mandibular condyles for diagnosis. In this study, we investigated whether this limitation was inherent to CBCT by comparing CBCT with multislice computed tomography (CT), and whether image segmentation and color mapping could overcome this limitation. METHODS: Nine fresh pig heads (18 condyles, 36 medial and lateral condylar regions) were used. Small osseous defects (diameter and depth, 1.5 mm) were created at the medial and lateral regions of the condyles shown by gutta percha markers. After the overlying soft tissues were restored, the pig heads underwent orthodontic-grade CBCT scans (0.4-mm voxel size; i-CAT; Imaging Sciences International, Hatfield, Pa) and medical-grade CT scans (0.625-mm voxel size; LightSpeed; GE, Little Chalfont, Buckinghamshire, United Kingdom). Subsequently, 2 calibrated and blinded raters diagnosed the defect numbers in each condylar region from CBCT and CT images using Dolphin 3D software (Patterson Supply, St Paul, Minn) without image segmentation, and then 1 week later with the proprietary image segmentation and color mapping tools of Dolphin 3D. Condylar polyvinyl siloxane impressions were collected and evaluated by the same raters to obtain physical diagnoses. Rediagnoses were made on randomly selected subsamples to assess reliability. Using the physical diagnoses as references, the accuracy of imaging diagnosis was assessed and statistically compared among the varied imaging and analysis methods. RESULTS: Image diagnoses of all imaging and analysis methods showed good or excellent intrarater and interrater reliability values, except for those of the segmented CBCT images, which were substantially lower. The numbers of overdiagnoses and underdiagnoses per condylar region were not significantly different among the varied imaging and analysis methods (Wilcoxon tests, P >0.05), but classification functions demonstrated substantially lower sensitivity and accuracy with CBCT than with CT. Logistic regression also showed that CT had a significantly higher probability (odds ratio, 2.4) than CBCT in reaching the correct diagnosis, whereas use of the image segmentation and color mapping tool proprietary to Dolphin 3D did not improve the diagnostic accuracy from CBCT images. CONCLUSIONS: Even at a lower voxel size than medical CT images, orthodontic-grade CBCT images of mandibular condyles may be inherently less reliable and less accurate for the diagnosis of small condylar defects.

The Role and Function of the Liaison Officer: Lessons Learned and Applied after Superstorm Sandy.

In October 2012, Superstorm Sandy had a wide impact on the public across New York City (NYC). The NYC Department of Health and Mental Hygiene (DOHMH) activated its incident command system (ICS) and deployed a liaison officer (LNO) to the NYC Emergency Operations Center (EOC) at NYC Emergency Management (NYCEM) 24 hours a day for 6 weeks. This prolonged response period, coupled with environmental effects on NYC's coastal communities, increased public awareness of Sandy's health impacts, requiring a broad scope of interagency coordination and operational input from the liaison officer. Liaison officers involved in this response later conducted a content analysis of issues handled throughout Sandy, to better understand the skill set required to serve in this role, identify greater staff depth, integrate liaison officers into DOHMH exercises, and update just-in-time training provided before liaison officers deploy. This analysis revealed defined training topics for liaison officers to improve staff performance and effectiveness in leading interagency coordination during emergency responses. Topics include resources, staffing, data management, public messaging, and vulnerable populations, and these topics have since been used to revamp liaison officer training and guide policy changes in the liaison officer job charter. Targeted use of liaison officers to support development and implementation and to coordinate response objectives with local, state, and federal partners has only become more important. This analysis continues to influence how DOHMH defines its citywide agency response role, to inform how best to staff and train liaison officers to respond, and to pose lessons for other jurisdictions seeking to maximize the effectiveness of liaison officers deployed in emergencies.

Abruptio placentae associated with misoprostol use in women with preeclampsia.

OBJECTIVE: To evaluate complications associated with cervical ripening with vaginal administration of misoprostol and dinoprostone vaginal inserts in women with preeclampsia. preeclampsia. STUDY DESIGN: Retrospective study of patients with preeclampsia undergoing cervical ripening with vaginal misoprostol and dinoprostone vaginal inserts prior to labor induction. RESULTS: Among 203 patients with preeclampsia undergoing cervical ripening prior to induction, 95 received vaginal misoprostol, and 108 received dinoprostone. The incidence of uterine hyperstimulation requiring medical therapy and the need for emergency cesarean section due tofetal heart rate abnormalities were significantly higher among patients receiving misoprostol (22.1% versus 12.0%, p = 0.04, and 17.9% versus 8.3%, p = 0.03, respectively). The overall incidence of abruptio placentae was 7.4%, with a significantly higher incidence among those receiving misoprostol as compared to dinoprostone (13.7% versus 1.9%, p = 0.001). CONCLUSION: Among patients with preeclampsia undergoing cervical ripening prior to labor induction, there is a higher incidence of acute intrapartum complications (uterine hyperstimulation, cesarean section for fetal heart rate abnormalities and abruptio placentae) with vaginal misoprostol, as compared to dinoprostone, vaginal insert.

Rapid invasion of anthropogenic CO2 into the deep circulation of the Weddell Gyre.

Data are presented for total carbon dioxide (TCO2), oxygen and nutrients from 14 cruises covering two repeat sections across the Weddell Gyre, from 1973 to 2010. Assessments of the rate of increase in anthropogenic CO2 (Cant) are made at three locations. Along the Prime Meridian, TCO2 is observed to steadily increase in the bottom water. Accompanying changes in silicate, nitrate and oxygen confirm the non-steady state of the Weddell circulation. The rate of increase in TCO2 of +0.12±0.05 µmol kg(-1) yr(-1) therefore poses an upper limit to the rate of increase in Cant. By contrast, the bottom water located in the central Weddell Sea exhibits no significant increase in TCO2, suggesting that this water is less well ventilated at the southern margins of the Weddell Sea. At the tip of the Antarctic Peninsula (i.e. the formation region of the bottom water found at the Prime Meridian), the high rate of increase in TCO2 over time observed at the lowest temperatures suggests that nearly full equilibration occurs with the anthropogenic CO2 of the atmosphere. This observation constitutes rare evidence for the possibility that ice cover is not a major impediment for uptake of Cant in this prominent deep water formation region.

Femoral-based central venous oxygen saturation is not a reliable substitute for subclavian/internal jugular-based central venous oxygen saturation in patients who are critically ill.

BACKGROUND: Central venous oxygen saturation (Scv(O(2))) has been used as a surrogate marker for mixed venous oxygen saturation (Sv(O(2))). Femoral venous oxygen saturation (Sfv(O(2))) is sometimes used as a substitute for Scv(O(2)). The purpose of this study is to test the hypothesis that these values can be used interchangeably in a population of patients who are critically ill. METHODS: We conducted a survey to assess the frequency of femoral line insertion during the initial treatment of patients who are critically ill. Scv(O(2)) vs Sfv(O(2)) STUDY: Patients with femoral and nonfemoral central venous catheters (CVCs) were included in this prospective study. Two sets of paired blood samples were drawn simultaneously from the femoral and nonfemoral CVCs. Blood samples were analyzed for oxygen saturation and lactate. RESULTS: One hundred and fifty physicians responded to the survey. More than one-third of the physicians insert a femoral line at least 10% of the time during the initial treatment of patients who were critically ill. Scv(O(2)) vs Sfv(O(2)) STUDY: Thirty-nine patients were enrolled. The mean Scv(O(2)) and Sfv(O(2)) were 73.1% +/- 11.6% and 69.1% +/- 12.9%, respectively (P = .002), with a mean bias of 4.0% +/- 11.2% (95% limits of agreement: -18.4% to 26.4%). The mean serum lactate from the nonfemoral and femoral CVCs was 2.84 +/- 4.0 and 2.72 +/- 3.2, respectively (P = .15). CONCLUSIONS: This study revealed a significant difference between paired samples of Scv(O(2)) and Sfv(O(2)). More than 50% of Scv(O(2)) and Sfv(O(2)) values diverged by > 5%. Sfv(O(2)) is not always a reliable substitute for Scv(O(2)) and should not routinely be used in protocols to help guide resuscitation.

Implementation and evaluation of a cognitive-behavioral intervention to prevent problem behavior in a disorganized school.

We assessed the effectiveness of two realizations of cognitive-behavioral instruction in an inner-city middle school with high rates of absenteeism, low staff morale, and chronic low academic achievement. Implementation measures showed that 68% of intended instruction was delivered in the first realization. Self-report measures showed improved school conduct, less victimization in school, and more positive peer associations for the treatment group than for the comparison group at the end of the school year. Treatment students were less likely to leave the school than were comparison students, but were more often absent and tardy. Implementation was poorer in the second realization, and there were no treatment-comparison differences on self-reports or teacher ratings, but treatment students less often left the school. Difficulties in conducting instruction in difficult settings may limit the effectiveness of otherwise efficacious interventions. Specific intervention programs may offer minimal benefits if more basic school improvements are not achieved.