Detalhe da pesquisa
1.
Inhibition of Heat Shock Protein 90 Prevents HIV Rebound.
J Biol Chem
; 291(19): 10332-46, 2016 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26957545
2.
Oral administration of the nucleoside EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine) provides rapid suppression of HIV viremia in humanized mice and favorable pharmacokinetic properties in mice and the rhesus macaque.
Antimicrob Agents Chemother
; 59(7): 4190-8, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25941222
3.
Impaired surfactant production by alveolar epithelial cells in a SCID-hu lung mouse model of congenital human cytomegalovirus infection.
J Virol
; 86(23): 12795-805, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22973041
4.
Impaired infectivity of ritonavir-resistant HIV is rescued by heat shock protein 90AB1.
J Biol Chem
; 286(28): 24581-92, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21602280
5.
Cellular HIV Reservoirs and Viral Rebound from the Lymphoid Compartments of 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine (EFdA)-Suppressed Humanized Mice.
Viruses
; 11(3)2019 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30871222
6.
Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter.
AIDS Res Ther
; 4: 24, 2007 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-17941994
7.
HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors.
AIDS Res Ther
; 2: 8, 2005 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-16207371
8.
Efficacy of broadly neutralizing monoclonal antibody PG16 in HIV-infected humanized mice.
Virology
; 462-463: 115-25, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24971704
9.
Heat shock protein 90AB1 and hyperthermia rescue infectivity of HIV with defective cores.
Virology
; 436(1): 162-72, 2013 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23200770
10.
Superior human leukocyte reconstitution and susceptibility to vaginal HIV transmission in humanized NOD-scid IL-2Rγ(-/-) (NSG) BLT mice.
Virology
; 417(1): 154-60, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21684569
11.
Potent activity of the HIV-1 maturation inhibitor bevirimat in SCID-hu Thy/Liv mice.
PLoS One
; 2(11): e1251, 2007 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-18043758
12.
Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication.
Mol Ther
; 11(5): 677-86, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15851006
13.
Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment).
J Virol
; 76(13): 6545-57, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12050367
14.
Mutations that confer resistance to template-analog inhibitors of human immunodeficiency virus (HIV) type 1 reverse transcriptase lead to severe defects in HIV replication.
J Virol
; 76(8): 4068-72, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11907245
15.
Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins.
J Virol
; 78(10): 5056-67, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15113887