Detalhe da pesquisa
1.
Exploring Individual Variability in Drug-Induced Liver Injury (DILI) Responses through Metabolomic Analysis.
Int J Mol Sci
; 25(5)2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38474249
2.
Enhancing the accuracy of mid-infrared spectroscopy-based liver steatosis quantification using digital image analysis as a reference.
Analyst
; 148(13): 3097-3106, 2023 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37313751
3.
Optimization of an adverse outcome pathway network on chemical-induced cholestasis using an artificial intelligence-assisted data collection and confidence level quantification approach.
J Biomed Inform
; 145: 104465, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37541407
4.
Quantitative Prediction of Steatosis in Patients with Non-Alcoholic Fatty Liver by Means of Hepatic MicroRNAs Present in Serum and Correlating with Hepatic Fat.
Int J Mol Sci
; 23(16)2022 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36012565
5.
Toward Rapid Screening of Liver Grafts at the Operating Room Using Mid-infrared Spectroscopy.
Anal Chem
; 92(21): 14542-14549, 2020 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33084322
6.
Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuclear receptors in human hepatocytes.
Arch Toxicol
; 94(2): 589-607, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31894354
7.
Angiopoietin-Like Protein 8 Is a Novel Vitamin D Receptor Target Gene Involved in Nonalcoholic Fatty Liver Pathogenesis.
Am J Pathol
; 188(12): 2800-2810, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30248338
8.
Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium.
Differentiation
; 93: 39-49, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27875772
9.
Hepatocyte vitamin D receptor regulates lipid metabolism and mediates experimental diet-induced steatosis.
J Hepatol
; 65(4): 748-757, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27245430
10.
Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis.
Toxicol Appl Pharmacol
; 302: 1-9, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27089845
11.
Repression of the nuclear receptor small heterodimer partner by steatotic drugs and in advanced nonalcoholic fatty liver disease.
Mol Pharmacol
; 87(4): 582-94, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25576488
12.
The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARα; and repressed by C/EBPα: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease.
Biochim Biophys Acta
; 1831(4): 803-18, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23318274
13.
Modulation of PI3K-LXRα-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin.
Lab Invest
; 94(3): 262-74, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24492281
14.
A simple transcriptomic signature able to predict drug-induced hepatic steatosis.
Arch Toxicol
; 88(4): 967-82, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24469900
15.
A quantitative weight-of-evidence method for confidence assessment of adverse outcome pathway networks: A case study on chemical-induced liver steatosis.
Toxicology
; 505: 153814, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38677583
16.
Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support.
Biomed Pharmacother
; 174: 116530, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38574623
17.
Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1.
JHEP Rep
; 6(1): 100918, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38192540
18.
Gut Microbiota and Plasma Bile Acids Associated with Non-Alcoholic Fatty Liver Disease Resolution in Bariatric Surgery Patients.
Nutrients
; 15(14)2023 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37513605
19.
Valproate and Short-Chain Fatty Acids Activate Transcription of the Human Vitamin D Receptor Gene through a Proximal GC-Rich DNA Region Containing Two Putative Sp1 Binding Sites.
Nutrients
; 14(13)2022 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35807853
20.
PTEN Deletion in Adult Mice Induces Hypoinsulinemia With Concomitant Low Glucose Levels.
Front Endocrinol (Lausanne)
; 13: 850214, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35282439