Detalhe da pesquisa
1.
Identification and Characterization of a Bacterial Periplasmic Solute Binding Protein That Binds l-Amino Acid Amides.
Biochemistry
; 63(10): 1322-1334, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38696389
2.
Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of Ideonella sakaiensis PETase and Variants with Improved Stability and Activity.
Biochemistry
; 62(2): 437-450, 2023 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35951410
3.
Drosophila melanogaster nonribosomal peptide synthetase Ebony encodes an atypical condensation domain.
Proc Natl Acad Sci U S A
; 116(8): 2913-2918, 2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30705105
4.
Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein.
Nat Chem Biol
; 14(6): 542-547, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29686357
5.
Structural Basis for the Allosteric Regulation of the SbtA Bicarbonate Transporter by the PII-like Protein, SbtB, from Cyanobium sp. PCC7001.
Biochemistry
; 58(50): 5030-5039, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31746199
6.
T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein.
PLoS Pathog
; 13(7): e1006469, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28759640
7.
Not always an innocent bystander: the impact of stabilised phosphopantetheine moieties when studying nonribosomal peptide biosynthesis.
Chem Commun (Camb)
; 59(53): 8234-8237, 2023 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37310188
8.
P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate.
Acta Pharm Sin B
; 13(8): 3561-3574, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37655329
9.
The role of oligomerization in the optimization of cyclohexadienyl dehydratase conformational dynamics and catalytic activity.
Protein Sci
; 31(12): e4510, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36382881
10.
Exploring Performance Parameters of Artificial Allosteric Protein Switches.
J Mol Biol
; 434(17): 167678, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35709893
11.
Ancestral sequence reconstruction for protein engineers.
Curr Opin Struct Biol
; 69: 131-141, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34023793
12.
Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes.
Cell Rep
; 35(2): 108996, 2021 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33852850
13.
Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity.
Nat Commun
; 12(1): 2511, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33947858
14.
Potent Cyclic Peptide Inhibitors of FXIIa Discovered by mRNA Display with Genetic Code Reprogramming.
J Med Chem
; 64(11): 7853-7876, 2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34044534
15.
Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme.
Nat Commun
; 11(1): 5945, 2020 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33230119
16.
Structural and evolutionary approaches to the design and optimization of fluorescence-based small molecule biosensors.
Curr Opin Struct Biol
; 57: 31-38, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30825845
17.
Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics.
Nat Commun
; 10(1): 2613, 2019 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31197182
18.
Investigating the size and dynamics of voltage-gated sodium channel fenestrations.
Channels (Austin)
; 8(3): 264-77, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24632677