Detalhe da pesquisa
1.
Pharmacokinetics and Safety of Lurbinectedin Administrated with Itraconazole in Cancer Patients: A Drug-Drug Interaction Study.
Mar Drugs
; 22(4)2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38667795
2.
Lurbinectedin in patients with pretreated endometrial cancer: results from a phase 2 basket clinical trial and exploratory translational study.
Invest New Drugs
; 41(5): 677-687, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37556023
3.
A phase I trial of lurbinectedin in combination with cisplatin in patients with advanced solid tumors.
Invest New Drugs
; 40(1): 91-98, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34453241
4.
Phase I study of lurbinectedin in combination with weekly paclitaxel with or without bevacizumab in patients with advanced solid tumors.
Invest New Drugs
; 40(6): 1263-1273, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35947247
5.
Efficacy and safety of lurbinectedin and doxorubicin in relapsed small cell lung cancer. Results from an expansion cohort of a phase I study.
Invest New Drugs
; 39(5): 1275-1283, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33704620
6.
Lurbinectedin versus pegylated liposomal doxorubicin or topotecan in patients with platinum-resistant ovarian cancer: A multicenter, randomized, controlled, open-label phase 3 study (CORAIL).
Gynecol Oncol
; 163(2): 237-245, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34521554
7.
Lurbinectedin in the treatment of relapsed small cell lung cancer.
Future Oncol
; 17(18): 2279-2289, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33736462
8.
Doxorubicin plus lurbinectedin in patients with advanced endometrial cancer: results from an expanded phase I study.
Int J Gynecol Cancer
; 31(11): 1428-1436, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34610971
9.
Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial.
Lancet Oncol
; 21(5): 645-654, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32224306
10.
Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma.
Ann Hematol
; 98(9): 2139-2150, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31240472
11.
ATLANTIS: a Phase III study of lurbinectedin/doxorubicin versus topotecan or cyclophosphamide/doxorubicin/vincristine in patients with small-cell lung cancer who have failed one prior platinum-containing line.
Future Oncol
; 15(3): 231-239, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30362375
12.
Phase I study of elisidepsin (Irvalec®) in combination with carboplatin or gemcitabine in patients with advanced malignancies.
Invest New Drugs
; 32(3): 500-9, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24395456
13.
Impact of a Moderate CYP3A4 Inducer (Bosentan) on Lurbinectedin Pharmacokinetics and Safety in Patients with Advanced Solid Tumors: An Open-Label, Two-Way, Crossover, Phase Ib Drug-Drug Interaction Study.
Pharmaceuticals (Basel)
; 17(2)2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38399397
14.
Lurbinectedin in patients with small cell lung cancer with chemotherapy-free interval ≥30 days and without central nervous metastases.
Lung Cancer
; 188: 107448, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38198859
15.
Phase I study of PM00104 (Zalypsis®) administered as a 1-hour weekly infusion resting every fourth week in patients with advanced solid tumors.
Invest New Drugs
; 31(3): 623-30, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22688291
16.
Phase I clinical and pharmacokinetic study of trabectedin and cisplatin given every three weeks in patients with advanced solid tumors.
Invest New Drugs
; 31(5): 1236-43, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23467812
17.
Multicenter phase II study of plitidepsin in patients with relapsed/refractory non-Hodgkin's lymphoma.
Haematologica
; 98(3): 357-63, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23065525
18.
Pooled Safety Analysis of Single-Agent Lurbinectedin in Patients With Advanced Solid Tumours.
Eur J Cancer
; 192: 113259, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37634282
19.
Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma.
Cancer Med
; 12(4): 3999-4009, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36127823
20.
Combination lurbinectedin and doxorubicin versus physician's choice of chemotherapy in patients with relapsed small-cell lung cancer (ATLANTIS): a multicentre, randomised, open-label, phase 3 trial.
Lancet Respir Med
; 11(1): 74-86, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36252599