Detalhe da pesquisa
1.
Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.
Nature
; 569(7755): 236-240, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31043745
2.
Membrane lipid remodeling modulates γ-secretase processivity.
J Biol Chem
; 299(4): 103027, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36805335
3.
The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene.
J Biol Chem
; 297(4): 101120, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450161
4.
Endotoxinemia Accelerates Atherosclerosis Through Electrostatic Charge-Mediated Monocyte Adhesion.
Circulation
; 143(3): 254-266, 2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33167684
5.
Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3.
Acta Neuropathol
; 139(1): 99-118, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31642962
6.
Modulating Hinge Flexibility in the APP Transmembrane Domain Alters γ-Secretase Cleavage.
Biophys J
; 116(11): 2103-2120, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31130234
7.
Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein.
Ann Neurol
; 84(2): 315-328, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30014603
8.
Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol.
Molecules
; 24(13)2019 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31247920
9.
Uncoupling proteins: Martin Klingenberg's contributions for 40â¯years.
Arch Biochem Biophys
; 657: 41-55, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30217511
10.
Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition.
EMBO Rep
; 17(9): 1314-25, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27461252
11.
Intramembrane proteolysis of ß-amyloid precursor protein by γ-secretase is an unusually slow process.
Biophys J
; 108(5): 1229-37, 2015 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25762334
12.
Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.
EMBO J
; 29(20): 3571-89, 2010 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20842103
13.
Generation of Alzheimer disease-associated amyloid ß42/43 peptide by γ-secretase can be inhibited directly by modulation of membrane thickness.
J Biol Chem
; 287(25): 21326-34, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22532566
14.
Polyphenolic compounds are novel protective agents against lipid membrane damage by α-synuclein aggregates in vitro.
Biochim Biophys Acta
; 1818(11): 2502-10, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22634381
15.
Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state.
Biophys J
; 102(7): 1646-55, 2012 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22500765
16.
Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region.
J Biol Chem
; 286(52): 45063-72, 2011 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22065584
17.
Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms.
J Neurosci
; 30(26): 8974-83, 2010 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20592218
18.
The Nicastrin ectodomain adopts a highly thermostable structure.
Biol Chem
; 392(11): 995-1001, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21848507
19.
Effective sample preparation procedure for the analysis of free neutral steroids, free steroid acids and sterol sulfates in different tissues by GC-MS.
J Steroid Biochem Mol Biol
; 211: 105880, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33757894
20.
Microbiota-derived short chain fatty acids modulate microglia and promote Aß plaque deposition.
Elife
; 102021 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33845942