RESUMO
BACKGROUND: The penetration of robotic technology in various surgical fields may increase ocular complications. METHODS: A systematic search was performed in both PubMed and Scopus databases. RESULTS: Eight articles were retrieved by the literature search. In total, 142 patients were included in the study. The most frequent complication was increased intra-ocular pressure. Corneal abrasion, ischaemic optic neuropathy and postoperative visual loss were also reported. The duration of operations was 1.7-9.9 h; mean intra-ocular pressure was 3.6-13.3 mmHg; estimated blood loss was 29.7-1200 ml; and administered intravenous fluids were 1.600-4.300 ml. CONCLUSIONS: Meticulous preoperative ophthalmological assessment, restriction of intravenous fluids, 'rest stops', eyelid taping and ocular dressings are the major protective measures suggested by the literature. Collaboration between the surgical team and the anaesthetist is also essential. Copyright © 2014 John Wiley & Sons, Ltd.
RESUMO
We report the case of a patient treated with dabrafenib and trametinib (mitogen-activated protein kinase pathway inhibitors) for stage 3b cutaneous melanoma who developed bilateral uveitis. Although there have been reports of ocular side effects with this class of drugs, uveitis has not been previously reported to the best of our knowledge. This case indicates the wide range of side effects that can be seen with the newer targeted biological therapies.
RESUMO
Idiopathic orbital inflammatory disease (IOID) is an idiopathic inflammatory process within the orbit that can result in permanent visual impairment. Although high-dose oral corticosteroids are currently the mainstay of therapy, their long-term usage can cause significant toxicity. We present a case of IOID that was successfully treated with the anti-CD20 monoclonal antibody rituximab following failed steroid sparing with conventional second-line immunosuppressive agents.