Detalhe da pesquisa
1.
The mechanism of action of tofacitinib - an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis.
Clin Exp Rheumatol
; 34(2): 318-28, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26966791
2.
Development of immunotoxicity testing strategies for immunomodulatory drugs.
Toxicol Pathol
; 40(2): 288-93, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22228792
3.
Immunological responses to exogenous insulin.
Endocr Rev
; 28(6): 625-52, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17785428
4.
Covalent binding of the nitroso metabolite of sulfamethoxazole is important in induction of drug-specific T-cell responses in vivo.
Mol Pharmacol
; 73(6): 1769-75, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18334600
5.
Optimization and validation of a flow cytometric method for immunophenotyping peripheral blood lymphocytes from cynomolgus monkeys (Macaca fascicularis).
Vet Clin Pathol
; 37(1): 42-8, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18366543
6.
Insulin antibodies with pulmonary delivery of insulin.
Diabetes Technol Ther
; 9 Suppl 1: S102-10, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17563298
7.
Assessing the potential to induce respiratory hypersensitivity.
Toxicol Sci
; 91(1): 4-13, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16339788
8.
In vitro cytokine release assays for predicting cytokine release syndrome: the current state-of-the-science. Report of a European Medicines Agency Workshop.
Cytokine
; 51(2): 213-5, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20471854
9.
Characterization of the draining lymph node response in the mouse drug allergy model: A model for drug hypersensitivity reactions.
J Immunotoxicol
; 12(4): 376-84, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25469456
10.
Development of a fluorescence-based in vivo phagocytosis assay to measure mononuclear phagocyte system function in the rat.
J Immunotoxicol
; 12(3): 239-46, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25027674
11.
Development and partial validation of a mouse model for predicting drug hypersensitivity reactions.
J Immunotoxicol
; 11(2): 141-7, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-23879792
12.
Development of a screening assay to evaluate the potential of drugs to cause immune-mediated hypersensitivity reactions.
J Immunotoxicol
; 11(2): 110-5, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-23768081
13.
Measuring T-cell responses against LCV and CMV in cynomolgus macaques using ELISPOT: potential application to non-clinical testing of immunomodulatory therapeutics.
J Immunotoxicol
; 11(1): 35-43, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-23461640
14.
Developmental immunotoxicity (DIT) testing of pharmaceuticals: current practices, state of the science, knowledge gaps, and recommendations.
J Immunotoxicol
; 9(2): 210-30, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22428536
15.
Human lymphocyte activation assay: an in vitro method for predictive immunotoxicity testing.
J Immunotoxicol
; 7(4): 357-66, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-21067467
16.
Synthesis and characterization of rhenium and technetium-99m labeled insulin.
J Med Chem
; 53(6): 2612-21, 2010 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20235598
17.
Summary of a workshop on nonclinical and clinical immunotoxicity assessment of immunomodulatory drugs.
J Immunotoxicol
; 6(1): 1-10, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19519157
18.
Use of an ex vivo local lymph node assay to assess contact hypersensitivity potential.
J Immunotoxicol
; 5(3): 271-7, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18830887
19.
Urinary corticosterone as an indicator of stress-mediated immunological changes in rats.
J Immunotoxicol
; 5(1): 17-22, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18382854
20.
Characterization of the action of drug-induced stress responses on the immune system: evaluation of biomarkers for drug-induced stress in rats.
J Immunotoxicol
; 4(1): 25-38, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18958710