Detalhe da pesquisa
1.
ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response.
Cell Mol Life Sci
; 79(12): 603, 2022 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36434396
2.
Novel eIF4A1 inhibitors with anti-tumor activity in lymphoma.
Mol Med
; 28(1): 101, 2022 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36058921
3.
From oncoproteins to spike proteins: the evaluation of intramolecular stability using hydropathic force field.
J Comput Aided Mol Des
; 36(11): 797-804, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36315295
4.
FOSL1 promotes metastasis of head and neck squamous cell carcinoma through super-enhancer-driven transcription program.
Mol Ther
; 29(8): 2583-2600, 2021 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33794365
5.
Elucidating the Interaction between Pyridoxine 5'-Phosphate Oxidase and Dopa Decarboxylase: Activation of B6-Dependent Enzyme.
Int J Mol Sci
; 24(1)2022 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36614085
6.
Structural understanding of 5-(4-hydroxy-phenyl)-N-(2-(5-methoxy-1H-indol-3-yl)-ethyl)-3-oxopentanamide as a neuroprotectant for Alzheimer's disease.
Bioorg Med Chem Lett
; 43: 128081, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33964442
7.
3D Interaction Homology: Hydropathic Analyses of the "π-Cation" and "π-π" Interaction Motifs in Phenylalanine, Tyrosine, and Tryptophan Residues.
J Chem Inf Model
; 61(6): 2937-2956, 2021 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34101460
8.
Functional diversification of the chemical landscapes of yeast Sec14-like phosphatidylinositol transfer protein lipid-binding cavities.
J Biol Chem
; 294(50): 19081-19098, 2019 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31690622
9.
Synthesis of novel 5-substituted-2-aminotetralin analogs: 5-HT1A and 5-HT7 G protein-coupled receptor affinity, 3D-QSAR and molecular modeling.
Bioorg Med Chem
; 28(3): 115262, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31882369
10.
3D interaction homology: The hydropathic interaction environments of even alanine are diverse and provide novel structural insight.
J Struct Biol
; 207(2): 183-198, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31112746
11.
Inhibiting Pneumococcal Surface Antigen A (PsaA) with Small Molecules Discovered through Virtual Screening: Steps toward Validating a Potential Target for Streptococcus pneumoniae.
Chem Biodivers
; 15(12): e1800234, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30221472
12.
Diaminopimelic acid (DAP) analogs bearing isoxazoline moiety as selective inhibitors against meso-diaminopimelate dehydrogenase (m-Ddh) from Porphyromonas gingivalis.
Bioorg Med Chem Lett
; 27(16): 3840-3844, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28668193
13.
Ortho group activation of a bromopyrrole ester in Suzuki-Miyaura cross-coupling reactions: Application to the synthesis of new microtubule depolymerizing agents with potent cytotoxic activities.
Bioorg Med Chem
; 25(12): 3206-3214, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28433513
14.
Crystal structure of carbonmonoxy sickle hemoglobin in R-state conformation.
J Struct Biol
; 194(3): 446-50, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27085422
15.
Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified through Structure-Based Design.
Mol Pharmacol
; 89(2): 287-96, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26655304
16.
Correction: Functional diversification of the chemical landscapes of yeast Sec14-like phosphatidylinositol transfer protein lipid-binding cavities.
J Biol Chem
; 295(5): 1368, 2020 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32005645
17.
Molecular basis of E. coli L-threonine aldolase catalytic inactivation at low pH.
Biochim Biophys Acta
; 1854(4): 278-83, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25560296
18.
Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP).
Bioorg Med Chem
; 24(12): 2707-15, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27156192
19.
3d interaction homology: The structurally known rotamers of tyrosine derive from a surprisingly limited set of information-rich hydropathic interaction environments described by maps.
Proteins
; 83(6): 1118-36, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25900573
20.
Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14ß-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands.
Bioorg Med Chem
; 23(8): 1701-15, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25783191