Detalhe da pesquisa
1.
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway.
Mol Cancer
; 22(1): 133, 2023 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37573301
2.
Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3.
Cell
; 133(5): 864-77, 2008 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-18510930
3.
A first-in-human Phase I dose-escalation trial of the novel therapeutic peptide, ALM201, demonstrates a favourable safety profile in unselected patients with ovarian cancer and other advanced solid tumours.
Br J Cancer
; 127(1): 92-101, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35568736
4.
Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer.
Br J Cancer
; 126(2): 247-258, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34728791
5.
Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma.
Gut
; 68(11): 1918-1927, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30852560
6.
Defining the molecular evolution of extrauterine high grade serous carcinoma.
Gynecol Oncol
; 155(2): 305-317, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31493898
7.
Prior knowledge transfer across transcriptional data sets and technologies using compositional statistics yields new mislabelled ovarian cell line.
Nucleic Acids Res
; 44(17): e137, 2016 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27353327
8.
Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage.
Mol Cell
; 35(3): 327-39, 2009 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19683496
9.
Clinical Application of Poly(ADP-Ribose) Polymerase Inhibitors in High-Grade Serous Ovarian Cancer.
Oncologist
; 21(5): 586-93, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27022037
10.
BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers.
Nucleic Acids Res
; 41(18): 8601-14, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863842
11.
Model selection for prognostic time-to-event gene signature discovery with applications in early breast cancer data.
Stat Appl Genet Mol Biol
; 12(5): 619-35, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24077567
12.
USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF.
Clin Transl Med
; 14(4): e1648, 2024 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38602256
13.
Integrated Multimodal Analyses of DNA Damage Response and Immune Markers as Predictors of Response in Metastatic Triple-Negative Breast Cancer in the TNT Trial (NCT00532727).
Clin Cancer Res
; 29(18): 3691-3705, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37574209
14.
Identification of Src as a Therapeutic Target in Oesophageal Adenocarcinoma through Functional Genomic and High-Throughput Drug Screening Approaches.
Cancers (Basel)
; 14(15)2022 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35954391
15.
A comprehensive systematic review and network meta-analysis: the role of anti-angiogenic agents in advanced epithelial ovarian cancer.
Sci Rep
; 12(1): 3803, 2022 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35264616
16.
Delivering a research-enabled multistakeholder partnership for enhanced patient care at a population level: The Northern Ireland Comprehensive Cancer Program.
Cancer
; 122(5): 664-73, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26695702
17.
BRCA1 is both a prognostic and predictive biomarker of response to chemotherapy in sporadic epithelial ovarian cancer.
Gynecol Oncol
; 123(3): 492-8, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21920589
18.
A DNA-damage immune response assay combined with PET biomarkers predicts response to neo-adjuvant chemotherapy and survival in oesophageal adenocarcinoma.
Sci Rep
; 11(1): 13061, 2021 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34158588
19.
The clinical and molecular significance associated with STING signaling in breast cancer.
NPJ Breast Cancer
; 7(1): 81, 2021 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34172750
20.
In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer.
Clin Cancer Res
; 27(1): 288-300, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33028592