Detalhe da pesquisa
1.
The impact of genomic distance on enhancer-promoter interactions at the CFTR locus.
J Cell Mol Med
; 28(4): e18142, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38372567
2.
An ectopic enhancer restores CFTR expression through de novo chromatin looping.
Gene Ther
; 30(6): 478-486, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36510002
3.
Transcriptomic analysis of lung development in wildtype and CFTR-/- sheep suggests an early inflammatory signature in the CF distal lung.
Funct Integr Genomics
; 23(2): 135, 2023 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37085733
4.
Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response.
Genes Dev
; 29(17): 1795-800, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26341557
5.
Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells.
Nucleic Acids Res
; 48(7): 3513-3524, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32095812
6.
OTX2 regulates CFTR expression during endoderm differentiation and occupies 3' cis-regulatory elements.
Dev Dyn
; 250(5): 684-700, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33386644
7.
Highly Efficient Gene Editing of Cystic Fibrosis Patient-Derived Airway Basal Cells Results in Functional CFTR Correction.
Mol Ther
; 28(7): 1684-1695, 2020 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32402246
8.
A functional genomics approach to investigate the differentiation of iPSCs into lung epithelium at air-liquid interface.
J Cell Mol Med
; 24(17): 9853-9870, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32692488
9.
Functional genomics analysis of human colon organoids identifies key transcription factors.
Physiol Genomics
; 52(6): 234-244, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32390556
10.
An organoid model to assay the role of CFTR in the human epididymis epithelium.
Cell Tissue Res
; 381(2): 327-336, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32377875
11.
Coordinate regulation of ELF5 and EHF at the chr11p13 CF modifier region.
J Cell Mol Med
; 23(11): 7726-7740, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31557407
12.
Regulatory dynamics of 11p13 suggest a role for EHF in modifying CF lung disease severity.
Nucleic Acids Res
; 45(15): 8773-8784, 2017 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28549169
13.
Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus.
Nucleic Acids Res
; 44(7): 3082-94, 2016 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26673704
14.
Quantitative Analysis of Dynamic Protein Interactions during Transcription Reveals a Role for Casein Kinase II in Polymerase-associated Factor (PAF) Complex Phosphorylation and Regulation of Histone H2B Monoubiquitylation.
J Biol Chem
; 291(26): 13410-20, 2016 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27143358
15.
Hepatocyte nuclear factor 1 coordinates multiple processes in a model of intestinal epithelial cell function.
Biochim Biophys Acta
; 1859(4): 591-8, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26855178
16.
Architectural proteins CTCF and cohesin have distinct roles in modulating the higher order structure and expression of the CFTR locus.
Nucleic Acids Res
; 42(15): 9612-22, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25081205
17.
FOXA2 regulates a network of genes involved in critical functions of human intestinal epithelial cells.
Physiol Genomics
; 47(7): 290-7, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25921584
18.
Nucleosome mapping across the CFTR locus identifies novel regulatory factors.
Nucleic Acids Res
; 41(5): 2857-68, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23325854
19.
Investigating adverse genomic and regulatory changes caused by replacement of the full-length CFTR cDNA using Cas9 and AAV.
Mol Ther Nucleic Acids
; 35(1): 102134, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38384445
20.
Transcriptional networks driving enhancer function in the CFTR gene.
Biochem J
; 446(2): 203-12, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22671145