Detalhe da pesquisa
1.
Intracellular vincristine levels in lymphoblasts affect treatment outcome in childhood B-lymphoblastic leukaemia: Ma-Spore ALL 2010 study.
Br J Clin Pharmacol
; 87(4): 1990-1999, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037681
2.
Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.
Genome Res
; 27(2): 185-195, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27903646
3.
Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy.
Blood
; 131(22): 2466-2474, 2018 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29572377
4.
Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry.
Blood
; 130(10): 1209-1212, 2017 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28659275
5.
Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse.
Blood
; 126(22): 2491-501, 2015 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26438511
6.
An international retrospective study for tolerability of 6-mercaptopurine on NUDT15 bi-allelic variants in children with acute lymphoblastic leukemia.
Haematologica
; 106(7): 2026-2029, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33504140
7.
Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations.
Blood
; 129(24): 3264-3268, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28408461
8.
Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia.
Exp Hematol
; : 104255, 2024 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38876252
9.
Deregulated MIR335 that targets MAPK1 is implicated in poor outcome of paediatric acute lymphoblastic leukaemia.
Br J Haematol
; 163(1): 93-103, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23888996
10.
Anthracycline-Free Protocol for Favorable-Risk Childhood ALL: A Noninferiority Comparison Between Malaysia-Singapore ALL 2003 and ALL 2010 Studies.
J Clin Oncol
; 41(20): 3642-3651, 2023 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37276496
11.
Digital PCR for Minimal Residual Disease Quantitation Using Immunoglobulin/T-Cell Receptor Gene Rearrangements in Acute Lymphoblastic Leukemia: A Proposed Analytic Algorithm.
J Mol Diagn
; 24(6): 655-665, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35390515
12.
FLT3 mutation and expression did not adversely affect clinical outcome of childhood acute leukaemia: a study of 531 Southeast Asian children by the Ma-Spore study group.
Hematol Oncol
; 29(4): 211-9, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21387358
13.
RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia.
Oncogene
; 40(4): 746-762, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33247204
14.
Practical Considerations for Using RNA Sequencing in Management of B-Lymphoblastic Leukemia: Malaysia-Singapore Acute Lymphoblastic Leukemia 2020 Implementation Strategy.
J Mol Diagn
; 23(10): 1359-1372, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34365011
15.
Distinct clinical characteristics of DUX4- and PAX5-altered childhood B-lymphoblastic leukemia.
Blood Adv
; 5(23): 5226-5238, 2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547766
16.
Identifying IGH disease clones for MRD monitoring in childhood B-cell acute lymphoblastic leukemia using RNA-Seq.
Leukemia
; 34(9): 2418-2429, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32099036
17.
TPMT*26 (208F-->L), a novel mutation detected in a Chinese.
Br J Clin Pharmacol
; 68(1): 120-3, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19660010
18.
Genomic subtyping and therapeutic targeting of acute erythroleukemia.
Nat Genet
; 51(4): 694-704, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30926971
19.
Intensifying Treatment of Childhood B-Lymphoblastic Leukemia With IKZF1 Deletion Reduces Relapse and Improves Overall Survival: Results of Malaysia-Singapore ALL 2010 Study.
J Clin Oncol
; 36(26): 2726-2735, 2018 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30044693
20.
NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.
Nat Genet
; 48(4): 367-73, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26878724