Detalhe da pesquisa
1.
Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA).
Nat Methods
; 8(1): 67-9, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21151135
2.
Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs.
Nucleic Acids Res
; 40(16): 8001-10, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22684503
3.
In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases.
Stem Cells
; 29(11): 1717-26, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21898685
4.
Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing.
Hum Gene Ther
; 26(7): 425-31, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26068112
5.
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.
Nat Biotechnol
; 33(2): 187-197, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25513782
6.
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing.
Nat Biotechnol
; 32(6): 569-76, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24770325
7.
Engineering customized TALE nucleases (TALENs) and TALE transcription factors by fast ligation-based automatable solid-phase high-throughput (FLASH) assembly.
Curr Protoc Mol Biol
; Chapter 12: Unit 12.16, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23821439
8.
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.
Nat Biotechnol
; 31(9): 822-6, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23792628
9.
Engineering designer transcription activator-like effector nucleases (TALENs) by REAL or REAL-Fast assembly.
Curr Protoc Mol Biol
; Chapter 12: Unit 12.15, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23026907
10.
FLASH assembly of TALENs for high-throughput genome editing.
Nat Biotechnol
; 30(5): 460-5, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22484455
11.
Evaluation of OPEN zinc finger nucleases for direct gene targeting of the ROSA26 locus in mouse embryos.
PLoS One
; 7(9): e41796, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22970113
12.
Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs).
PLoS One
; 7(5): e37877, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22655075
13.
Targeted gene disruption in somatic zebrafish cells using engineered TALENs.
Nat Biotechnol
; 29(8): 697-8, 2011 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822241