Detalhe da pesquisa
1.
HelixGAN a deep-learning methodology for conditional de novo design of α-helix structures.
Bioinformatics
; 39(1)2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36651657
2.
Gate-based quantum computing for protein design.
PLoS Comput Biol
; 19(4): e1011033, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37043517
3.
Targeting the Receptor-Binding Motif of SARS-CoV-2 with D-Peptides Mimicking the ACE2 Binding Helix: Lessons for Inhibiting Omicron and Future Variants of Concern.
J Chem Inf Model
; 62(15): 3618-3626, 2022 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35875887
4.
Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.
Mol Cell
; 53(1): 140-7, 2014 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24374310
5.
The geometric influence on the Cys2His2 zinc finger domain and functional plasticity.
Nucleic Acids Res
; 48(11): 6382-6402, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32383734
6.
Large-scale survey and database of high affinity ligands for peptide recognition modules.
Mol Syst Biol
; 16(12): e9310, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33438817
7.
Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB.
Proc Natl Acad Sci U S A
; 115(7): 1505-1510, 2018 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378946
8.
Strategies to Develop Inhibitors of Motif-Mediated Protein-Protein Interactions as Drug Leads.
Annu Rev Pharmacol Toxicol
; 57: 39-60, 2017 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27618737
9.
A Method to Calculate the Relative Binding Free Energy Differences of α-Helical Stapled Peptides.
J Org Chem
; 85(3): 1644-1651, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31893470
10.
Tissue-specific alternative splicing remodels protein-protein interaction networks.
Mol Cell
; 46(6): 884-92, 2012 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22749401
11.
Predicting changes in protein stability caused by mutation using sequence-and structure-based methods in a CAGI5 blind challenge.
Hum Mutat
; 40(9): 1414-1423, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31243847
12.
Evaluating the predictions of the protein stability change upon single amino acid substitutions for the FXN CAGI5 challenge.
Hum Mutat
; 40(9): 1392-1399, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31209948
13.
Rapid and accurate structure-based therapeutic peptide design using GPU accelerated thermodynamic integration.
Proteins
; 87(3): 236-244, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30520126
14.
Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes.
Genes Dev
; 25(7): 767-78, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21460040
15.
A high-throughput pipeline for the production of synthetic antibodies for analysis of ribonucleoprotein complexes.
RNA
; 22(4): 636-55, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26847261
16.
Pooled screening for antiproliferative inhibitors of protein-protein interactions.
Nat Chem Biol
; 12(4): 275-81, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26900867
17.
Data driven flexible backbone protein design.
PLoS Comput Biol
; 13(8): e1005722, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28837553
18.
ELASPIC web-server: proteome-wide structure-based prediction of mutation effects on protein stability and binding affinity.
Bioinformatics
; 32(10): 1589-91, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26801957
19.
JBASE: Joint Bayesian Analysis of Subphenotypes and Epistasis.
Bioinformatics
; 32(2): 203-10, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26411870
20.
A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity.
Nucleic Acids Res
; 43(19): 9147-57, 2015 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26384429