Detalhe da pesquisa
1.
Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair.
Mol Cell
; 83(20): 3679-3691.e8, 2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37797621
2.
BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation.
EMBO J
; 42(15): e113565, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37305927
3.
BRCA1/BARD1 is a nucleosome reader and writer.
Trends Biochem Sci
; 47(7): 582-595, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35351360
4.
A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-methylated DNA-Dependent Histone Ubiquitylation.
Mol Cell
; 72(4): 753-765.e6, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30392931
5.
Disordered region encodes α-crystallin chaperone activity toward lens client γD-crystallin.
Proc Natl Acad Sci U S A
; 120(6): e2213765120, 2023 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719917
6.
Conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans.
Nucleic Acids Res
; 51(5): 2108-2116, 2023 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36250637
7.
Who with whom: functional coordination of E2 enzymes by RING E3 ligases during poly-ubiquitylation.
EMBO J
; 39(22): e104863, 2020 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33015833
8.
Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature
; 557(7707): 729-733, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29795346
9.
Toggle switch residues control allosteric transitions in bacterial adhesins by participating in a concerted repacking of the protein core.
PLoS Pathog
; 17(4): e1009440, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33826682
10.
Release of a disordered domain enhances HspB1 chaperone activity toward tau.
Proc Natl Acad Sci U S A
; 117(6): 2923-2929, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31974309
11.
The BRCA1/BARD1 ubiquitin ligase and its substrates.
Biochem J
; 478(18): 3467-3483, 2021 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34591954
12.
Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability.
Nat Chem Biol
; 15(1): 62-70, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30531907
13.
Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.
Nature
; 517(7533): 223-6, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25327252
14.
Solution structure of sperm lysin yields novel insights into molecular dynamics of rapid protein evolution.
Proc Natl Acad Sci U S A
; 115(6): 1310-1315, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29348201
15.
De novo mutation in RING1 with epigenetic effects on neurodevelopment.
Proc Natl Acad Sci U S A
; 115(7): 1558-1563, 2018 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29386386
16.
BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes.
Proc Natl Acad Sci U S A
; 115(6): 1316-1321, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29367421
17.
UbcH5 Interacts with Substrates to Participate in Lysine Selection with the E3 Ubiquitin Ligase CHIP.
Biochemistry
; 59(22): 2078-2088, 2020 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32401531
18.
HSPB5 engages multiple states of a destabilized client to enhance chaperone activity in a stress-dependent manner.
J Biol Chem
; 294(9): 3261-3270, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30567736
19.
The ubiquitin ligase SspH1 from Salmonella uses a modular and dynamic E3 domain to catalyze substrate ubiquitylation.
J Biol Chem
; 294(3): 783-793, 2019 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30459234
20.
RMSD analysis of structures of the bacterial protein FimH identifies five conformations of its lectin domain.
Proteins
; 88(4): 593-603, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31622514