Detalhe da pesquisa
1.
Small-molecule IKKß activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.
Proc Natl Acad Sci U S A
; 119(18): e2115071119, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35476515
2.
Exon skipping induced by CRISPR-directed gene editing regulates the response to chemotherapy in non-small cell lung carcinoma cells.
Gene Ther
; 29(6): 357-367, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35314779
3.
Precise and error-prone CRISPR-directed gene editing activity in human CD34+ cells varies widely among patient samples.
Gene Ther
; 28(1-2): 105-113, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32873924
4.
On the Origins of Homology Directed Repair in Mammalian Cells.
Int J Mol Sci
; 22(7)2021 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33805897
5.
Genetic spell-checking: gene editing using single-stranded DNA oligonucleotides.
Plant Biotechnol J
; 14(2): 463-70, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26402400
6.
Strand bias influences the mechanism of gene editing directed by single-stranded DNA oligonucleotides.
Nucleic Acids Res
; 39(11): 4783-94, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21343181
7.
CRISPR-Directed Gene Editing as a Method to Reduce Chemoresistance in Lung Cancer Cells.
Methods Mol Biol
; 2660: 263-271, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37191803
8.
Review of Safety Data for Adenovirus 5 as a Delivery Vector for Intratumoral Cancer Gene Therapy.
Hum Gene Ther
; 34(7-8): 314-324, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36851898
9.
Homology directed correction, a new pathway model for point mutation repair catalyzed by CRISPR-Cas.
Sci Rep
; 12(1): 8132, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35581233
10.
Regulation of targeted gene repair by intrinsic cellular processes.
Bioessays
; 31(2): 159-68, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19204988
11.
Deconvolution of Complex DNA Repair (DECODR): Establishing a Novel Deconvolution Algorithm for Comprehensive Analysis of CRISPR-Edited Sanger Sequencing Data.
CRISPR J
; 4(1): 120-131, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571043
12.
A stable G-quartet binds to a huntingtin protein fragment containing expanded polyglutamine tracks.
J Neurosci Res
; 88(2): 335-45, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19705452
13.
Modeling pediatric AML FLT3 mutations using CRISPR/Cas12a- mediated gene editing.
Leuk Lymphoma
; 61(13): 3078-3088, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32815753
14.
The Diversity of Genetic Outcomes from CRISPR/Cas Gene Editing is Regulated by the Length of the Symmetrical Donor DNA Template.
Genes (Basel)
; 11(10)2020 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33008045
15.
Perspectives on Molecular Diagnostic Testing for the COVID-19 Pandemic in Delaware.
Dela J Public Health
; 6(2): 20-24, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34467103
16.
gRNA Sequence Heterology Tolerance Catalyzed by CRISPR/Cas in an In Vitro Homology-Directed Repair Reaction.
Mol Ther Nucleic Acids
; 20: 568-579, 2020 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32330873
17.
Kinetics of Nuclear Uptake and Site-Specific DNA Cleavage during CRISPR-Directed Gene Editing in Solid Tumor Cells.
Mol Cancer Res
; 18(6): 891-902, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32184217
18.
Genetic correction of splice site mutation in purified and enriched myoblasts isolated from mdx5cv mice.
BMC Mol Biol
; 10: 15, 2009 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19236710
19.
DNA breakage and induction of DNA damage response proteins precede the appearance of visible mutant huntingtin aggregates.
J Neurosci Res
; 87(3): 733-47, 2009 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18831068
20.
DNA breakage associated with targeted gene alteration directed by DNA oligonucleotides.
Mutat Res
; 669(1-2): 85-94, 2009 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-19463835