Detalhe da pesquisa
1.
Effect of Cefepime/Enmetazobactam vs Piperacillin/Tazobactam on Clinical Cure and Microbiological Eradication in Patients With Complicated Urinary Tract Infection or Acute Pyelonephritis: A Randomized Clinical Trial.
JAMA
; 328(13): 1304-1314, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36194218
2.
Sigmoid Emax Modeling To Define the Fixed Concentration of Enmetazobactam for MIC Testing in Combination with Cefepime.
Antimicrob Agents Chemother
; 65(8): e0092621, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34097479
3.
Pharmacokinetics-Pharmacodynamics of Enmetazobactam Combined with Cefepime in a Neutropenic Murine Thigh Infection Model.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32253212
4.
Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum-ß-Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia Caused by ESBL-Producing Klebsiella pneumoniae.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32253209
5.
Intrapulmonary Pharmacokinetics of Cefepime and Enmetazobactam in Healthy Volunteers: Towards New Treatments for Nosocomial Pneumonia.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33077666
6.
In Vitro Activity of Cefepime-Enmetazobactam against Gram-Negative Isolates Collected from U.S. and European Hospitals during 2014-2015.
Antimicrob Agents Chemother
; 63(7)2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30988152
7.
Development of Broth Microdilution MIC and Disk Diffusion Antimicrobial Susceptibility Test Quality Control Ranges for the Combination of Cefepime and the Novel ß-Lactamase Inhibitor Enmetazobactam.
J Clin Microbiol
; 57(8)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31167844
8.
The natural diyne-furan fatty acid EV-086 is an inhibitor of fungal delta-9 fatty acid desaturation with efficacy in a model of skin dermatophytosis.
Antimicrob Agents Chemother
; 58(1): 455-66, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24189258
9.
Impact of surfactants and other body fluids on in vitro activity of a novel ß-lactamase inhibitor enmetazobactam in combination with cefepime against clinical isolates of Klebsiella pneumoniae.
J Antibiot (Tokyo)
; 76(3): 183-189, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36690707
10.
Third-generation cephalosporin resistance in clinical isolates of Enterobacterales collected between 2016-2018 from USA and Europe: genotypic analysis of ß-lactamases and comparative in vitro activity of cefepime/enmetazobactam.
J Glob Antimicrob Resist
; 25: 93-101, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33746112
11.
Yeast artificial chromosomes employed for random assembly of biosynthetic pathways and production of diverse compounds in Saccharomyces cerevisiae.
Microb Cell Fact
; 8: 45, 2009 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19678954
12.
The Paxillin-like protein AgPxl1 is required for apical branching and maximal hyphal growth in A.gossypii.
Fungal Genet Biol
; 45(6): 829-38, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18448364
13.
Maximal polar growth potential depends on the polarisome component AgSpa2 in the filamentous fungus Ashbya gossypii.
Mol Biol Cell
; 14(10): 4140-54, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12937275
14.
A Ras-like GTPase is involved in hyphal growth guidance in the filamentous fungus Ashbya gossypii.
Mol Biol Cell
; 15(10): 4622-32, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15282338
15.
Phosphatidylinositol-dependent phospholipases C Plc2 and Plc3 of Candida albicans are dispensable for morphogenesis and host-pathogen interaction.
Res Microbiol
; 156(7): 822-9, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16040234
16.
The Yak1 kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans.
Mol Biol Cell
; 19(5): 2251-66, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18321992
17.
The SH3/PH domain protein AgBoi1/2 collaborates with the Rho-type GTPase AgRho3 to prevent nonpolar growth at hyphal tips of Ashbya gossypii.
Eukaryot Cell
; 5(10): 1635-47, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16950929