Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

ApoA-I Protects Pancreatic ß-Cells From Cholesterol-Induced Mitochondrial Damage and Restores Their Ability to Secrete Insulin.

Manandhar, Bikash; Pandzic, Elvis; Deshpande, Nandan; Chen, Sing-Young; Wasinger, Valerie C; Kockx, Maaike; Glaros, Elias N; Ong, Kwok Leung; Thomas, Shane R; Wilkins, Marc R; Whan, Renee M; Cochran, Blake J; Rye, Kerry-Anne.

Arterioscler Thromb Vasc Biol ; 44(2): e20-e38, 2024 02.

Artigo em Inglês | MEDLINE | ID: mdl-38095105

2.

Triglyceride-rich lipoprotein, remnant cholesterol, and apolipoproteins CII, CIII and E in patients with schizophrenia.

Wang, Jeffrey; Kockx, Maaike; Bolek, Magdalena; Lambert, Tim; Sullivan, David; Chow, Vincent; Kritharides, Leonard.

J Lipid Res ; : 100577, 2024 Jun 13.

Artigo em Inglês | MEDLINE | ID: mdl-38879166

3.

Identification of a Distinct Platelet Phenotype in the Elderly: ADP Hypersensitivity Coexists With Platelet PAR (Protease-Activated Receptor)-1 and PAR-4-Mediated Thrombin Resistance.

Gnanenthiran, Sonali R; Pennings, Gabrielle J; Reddel, Caroline J; Campbell, Heather; Kockx, Maaike; Hamilton, Justin R; Chen, Vivien M; Kritharides, Leonard.

Arterioscler Thromb Vasc Biol ; 42(8): 960-972, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35708029

4.

Increased ABCA1 (ATP-Binding Cassette Transporter A1)-Specific Cholesterol Efflux Capacity in Schizophrenia.

Luquain-Costaz, Céline; Kockx, Maaike; Anastasius, Malcolm; Chow, Vincent; Kontush, Anatol; Jessup, Wendy; Kritharides, Leonard.

Arterioscler Thromb Vasc Biol ; 40(11): 2728-2737, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32907370

5.

Free Thiol ß2-GPI (ß-2-Glycoprotein-I) Provides a Link Between Inflammation and Oxidative Stress in Atherosclerotic Coronary Artery Disease.

Weaver, James C; Ullah, Inaam; Qi, Miao; Giannakopoulos, Bill; Rye, Kerry Anne; Kockx, Maaike; Kritharides, Leonard; Krilis, Steven A.

Arterioscler Thromb Vasc Biol ; 40(11): 2794-2804, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32938215

6.

The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages.

Aleidi, Shereen M; Yang, Alryel; Sharpe, Laura J; Rao, Geetha; Cochran, Blake J; Rye, Kerry-Anne; Kockx, Maaike; Brown, Andrew J; Gelissen, Ingrid C.

Biochim Biophys Acta Mol Cell Biol Lipids ; 1863(4): 359-368, 2018 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-29306077

7.

Prolonged Intake of Dietary Lipids Alters Membrane Structure and T Cell Responses in LDLr-/- Mice.

Pollock, Abigail H; Tedla, Nicodemus; Hancock, Sarah E; Cornely, Rhea; Mitchell, Todd W; Yang, Zhengmin; Kockx, Maaike; Parton, Robert G; Rossy, Jérémie; Gaus, Katharina.

J Immunol ; 196(10): 3993-4002, 2016 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-27183636

8.

N-glycosylation of human sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is essential for stability, secretion and activity.

Traini, Mathew; Kumaran, Raani; Thaysen-Andersen, Morten; Kockx, Maaike; Jessup, Wendy; Kritharides, Leonard.

Biochem J ; 474(7): 1071-1092, 2017 03 08.

Artigo em Inglês | MEDLINE | ID: mdl-28104755

9.

Human macrophage cathepsin B-mediated C-terminal cleavage of apolipoprotein A-I at Ser228 severely impairs antiatherogenic capacity.

Dinnes, Donna Lee M; White, Melanie Y; Kockx, Maaike; Traini, Mathew; Hsieh, Victar; Kim, Mi-Jurng; Hou, Liming; Jessup, Wendy; Rye, Kerry-Anne; Thaysen-Andersen, Morten; Cordwell, Stuart J; Kritharides, Leonard.

FASEB J ; 30(12): 4239-4255, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27630170

10.

HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export.

Du, Xian-Ming; Kim, Mi-Jurng; Hou, Liming; Le Goff, Wilfried; Chapman, M John; Van Eck, Miranda; Curtiss, Linda K; Burnett, John R; Cartland, Sian P; Quinn, Carmel M; Kockx, Maaike; Kontush, Anatol; Rye, Kerry-Anne; Kritharides, Leonard; Jessup, Wendy.

Circ Res ; 116(7): 1133-42, 2015 Mar 27.

Artigo em Inglês | MEDLINE | ID: mdl-25589556

11.

Low-Density Lipoprotein Receptor-Dependent and Low-Density Lipoprotein Receptor-Independent Mechanisms of Cyclosporin A-Induced Dyslipidemia.

Kockx, Maaike; Glaros, Elias; Leung, Betty; Ng, Theodore W; Berbée, Jimmy F P; Deswaerte, Virginie; Nawara, Diana; Quinn, Carmel; Rye, Kerry-Anne; Jessup, Wendy; Rensen, Patrick C N; Meikle, Peter J; Kritharides, Leonard.

Arterioscler Thromb Vasc Biol ; 36(7): 1338-49, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-27150391

12.

Cholesterol efflux capacity: An introduction for clinicians.

Anastasius, Malcolm; Kockx, Maaike; Jessup, Wendy; Sullivan, David; Rye, Kerry-Anne; Kritharides, Leonard.

Am Heart J ; 180: 54-63, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-27659883

13.

Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages.

Traini, Mathew; Quinn, Carmel M; Sandoval, Cecilia; Johansson, Erik; Schroder, Kate; Kockx, Maaike; Meikle, Peter J; Jessup, Wendy; Kritharides, Leonard.

J Biol Chem ; 289(47): 32895-913, 2014 Nov 21.

Artigo em Inglês | MEDLINE | ID: mdl-25288789

14.

Cellular cholesterol regulates ubiquitination and degradation of the cholesterol export proteins ABCA1 and ABCG1.

Hsieh, Victar; Kim, Mi-Jurng; Gelissen, Ingrid C; Brown, Andrew J; Sandoval, Cecilia; Hallab, Jeannette C; Kockx, Maaike; Traini, Mathew; Jessup, Wendy; Kritharides, Leonard.

J Biol Chem ; 289(11): 7524-36, 2014 Mar 14.

Artigo em Inglês | MEDLINE | ID: mdl-24500716

15.

Protein kinase C controls vesicular transport and secretion of apolipoprotein E from primary human macrophages.

Karunakaran, Denuja; Kockx, Maaike; Owen, Dylan M; Burnett, John R; Jessup, Wendy; Kritharides, Leonard.

J Biol Chem ; 288(7): 5186-97, 2013 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-23288845

16.

Intestinal cholesterol absorption.

Kockx, Maaike; Kritharides, Leonard.

Curr Opin Lipidol ; 29(6): 484-485, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30239352

17.

Cholesterol accumulation inhibits ER to Golgi transport and protein secretion: studies of apolipoprotein E and VSVGt.

Kockx, Maaike; Dinnes, Donna L; Huang, Kuan-Yen; Sharpe, Laura J; Jessup, Wendy; Brown, Andrew J; Kritharides, Leonard.

Biochem J ; 447(1): 51-60, 2012 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-22747346

18.

Protein kinase A modulates the activity of a major human isoform of ABCG1.

Gelissen, Ingrid C; Sharpe, Laura J; Sandoval, Cecilia; Rao, Geetha; Kockx, Maaike; Kritharides, Leonard; Jessup, Wendy; Brown, Andrew J.

J Lipid Res ; 53(10): 2133-2140, 2012 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22872754

19.

Glycosylation and sialylation of macrophage-derived human apolipoprotein E analyzed by SDS-PAGE and mass spectrometry: evidence for a novel site of glycosylation on Ser290.

Lee, Youra; Kockx, Maaike; Raftery, Mark J; Jessup, Wendy; Griffith, Renate; Kritharides, Leonard.

Mol Cell Proteomics ; 9(9): 1968-81, 2010 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-20511397

20.

Hyperlipidaemia in immunosuppression.