Detalhe da pesquisa
1.
The discovery of indole full agonists of the neurotensin receptor 1 (NTSR1).
Bioorg Med Chem Lett
; 24(16): 3974-8, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24997685
2.
Synthesis and SAR of novel isoxazoles as potent c-jun N-terminal kinase (JNK) inhibitors.
Bioorg Med Chem Lett
; 24(1): 161-4, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24332487
3.
Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker.
Bioorg Med Chem
; 21(21): 6642-9, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23993674
4.
Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) inhibitors.
Bioorg Med Chem Lett
; 21(6): 1719-23, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21316221
5.
Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors.
Bioorg Med Chem Lett
; 21(9): 2732-5, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21185177
6.
Characterization of dasatinib and its structural analogs as CYP3A4 mechanism-based inactivators and the proposed bioactivation pathways.
Drug Metab Dispos
; 37(6): 1242-50, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19282395
7.
Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors.
Bioorg Med Chem Lett
; 19(12): 3344-7, 2009 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19433357
8.
Discovery and Optimization of a Series of Sulfonamide Inverse Agonists for the Retinoic Acid Receptor-Related Orphan Receptor-α.
Med Chem
; 15(6): 676-684, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30799793
9.
Design, Synthesis, and Biological Evaluation of Indole Biphenylcarboxylic Acids as PPARγ Antagonists.
ACS Med Chem Lett
; 6(9): 998-1003, 2015 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26396687
10.
A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases.
ACS Chem Biol
; 8(8): 1747-54, 2013 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23751758
11.
PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.
Cancer Biol Ther
; 9(10): 764-77, 2010 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20234191