Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

A Phase IIa Controlled Human Malaria Infection and Immunogenicity Study of RTS,S/AS01E and RTS,S/AS01B Delayed Fractional Dose Regimens in Malaria-Naive Adults.

Moon, James E; Ockenhouse, Christian; Regules, Jason A; Vekemans, Johan; Lee, Cynthia; Chuang, Ilin; Traskine, Magali; Jongert, Erik; Ivinson, Karen; Morelle, Danielle; Komisar, Jack L; Lievens, Marc; Sedegah, Martha; Garver, Lindsey S; Sikaffy, April K; Waters, Norman C; Ballou, William Ripley; Ofori-Anyinam, Opokua.

J Infect Dis ; 222(10): 1681-1691, 2020 10 13.

Artigo em Inglês | MEDLINE | ID: mdl-32687161

2.

Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study.

Regules, Jason A; Cicatelli, Susan B; Bennett, Jason W; Paolino, Kristopher M; Twomey, Patrick S; Moon, James E; Kathcart, April K; Hauns, Kevin D; Komisar, Jack L; Qabar, Aziz N; Davidson, Silas A; Dutta, Sheetij; Griffith, Matthew E; Magee, Charles D; Wojnarski, Mariusz; Livezey, Jeffrey R; Kress, Adrian T; Waterman, Paige E; Jongert, Erik; Wille-Reece, Ulrike; Volkmuth, Wayne; Emerling, Daniel; Robinson, William H; Lievens, Marc; Morelle, Danielle; Lee, Cynthia K; Yassin-Rajkumar, Bebi; Weltzin, Richard; Cohen, Joe; Paris, Robert M; Waters, Norman C; Birkett, Ashley J; Kaslow, David C; Ballou, W Ripley; Ockenhouse, Christian F; Vekemans, Johan.

J Infect Dis ; 214(5): 762-71, 2016 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-27296848

3.

Measurement of parasitological data by quantitative real-time PCR from controlled human malaria infection trials at the Walter Reed Army Institute of Research.

Kamau, Edwin; Alemayehu, Saba; Feghali, Karla C; Komisar, Jack; Regules, Jason; Cowden, Jessica; Ockenhouse, Christian F.

Malar J ; 13: 288, 2014 Jul 28.

Artigo em Inglês | MEDLINE | ID: mdl-25066459

4.

Comparative evaluation of published real-time PCR assays for the detection of malaria following MIQE guidelines.

Alemayehu, Saba; Feghali, Karla C; Cowden, Jessica; Komisar, Jack; Ockenhouse, Christian F; Kamau, Edwin.

Malar J ; 12: 277, 2013 Aug 08.

Artigo em Inglês | MEDLINE | ID: mdl-23927553

5.

Plasmodium inui infection reduces the efficacy of a simian immunodeficiency virus DNA vaccine in a rhesus macaque model through alteration of the vaccine-induced immune response.

Yin, Jiangmei; Vahey, Maryanne T; Dai, Anlan; Lewis, Mark G; Arango, Tatiana; Yalley-Ogunro, Jake; Greenhouse, Jack; Mendoza, Karla; Khan, Amir; Sardesai, Niranjan Y; Weiss, Walter; Komisar, Jack; Boyer, Jean D.

J Infect Dis ; 206(4): 523-33, 2012 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-22693228

6.

Malaria vaccines.

Komisar, Jack L.

Front Biosci ; 12: 3928-55, 2007 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-17485348

7.

Phase 1/2a Trial of Plasmodium vivax Malaria Vaccine Candidate VMP001/AS01B in Malaria-Naive Adults: Safety, Immunogenicity, and Efficacy.

Bennett, Jason W; Yadava, Anjali; Tosh, Donna; Sattabongkot, Jetsumon; Komisar, Jack; Ware, Lisa A; McCarthy, William F; Cowden, Jessica J; Regules, Jason; Spring, Michele D; Paolino, Kristopher; Hartzell, Joshua D; Cummings, James F; Richie, Thomas L; Lumsden, Joanne; Kamau, Edwin; Murphy, Jittawadee; Lee, Cynthia; Parekh, Falgunee; Birkett, Ashley; Cohen, Joe; Ballou, W Ripley; Polhemus, Mark E; Vanloubbeeck, Yannick F; Vekemans, Johan; Ockenhouse, Christian F.

PLoS Negl Trop Dis ; 10(2): e0004423, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26919472

8.

Molecular cloning of the gyrA gene and characterization of its mutation in clinical isolates of quinolone-resistant Edwardsiella tarda.

Shin, Soon Bum; Yoo, Min Ho; Jeong, Joon Bum; Kim, Young Min; Chung, Joon-Ki; Huh, Min Do; Komisar, Jack L; Jeong, Hyun Do.

Dis Aquat Organ ; 67(3): 259-66, 2005 Nov 28.

Artigo em Inglês | MEDLINE | ID: mdl-16408842

9.

Ad35.CS.01-RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults.

Ockenhouse, Christian F; Regules, Jason; Tosh, Donna; Cowden, Jessica; Kathcart, April; Cummings, James; Paolino, Kristopher; Moon, James; Komisar, Jack; Kamau, Edwin; Oliver, Thomas; Chhoeu, Austin; Murphy, Jitta; Lyke, Kirsten; Laurens, Matthew; Birkett, Ashley; Lee, Cynthia; Weltzin, Rich; Wille-Reece, Ulrike; Sedegah, Martha; Hendriks, Jenny; Versteege, Isabella; Pau, Maria Grazia; Sadoff, Jerold; Vanloubbeeck, Yannick; Lievens, Marc; Heerwegh, Dirk; Moris, Philippe; Guerra Mendoza, Yolanda; Jongert, Erik; Cohen, Joe; Voss, Gerald; Ballou, W Ripley; Vekemans, Johan.

PLoS One ; 10(7): e0131571, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26148007

10.

Toxicity of the staphylococcal enterotoxin B mutants with histidine-to-tyrosine substitutions.

Korolev, Sergey; Pinelis, Dmitriy; Savransky, Vladimir; Komisar, Jack; Vogel, Peter; Fegeding, Konstantin.

Toxicology ; 187(2-3): 229-38, 2003 May 03.

Artigo em Inglês | MEDLINE | ID: mdl-12699911

11.

Use of qPCR and genomic sequencing to diagnose Plasmodium ovale wallikeri malaria in a returned soldier in the setting of a negative rapid diagnostic assay.

Cohen, Robert; Feghali, Karla; Alemayehu, Saba; Komisar, Jack; Hang, Jun; Weina, Peter J; Coggeshall, Patricia; Kamau, Edwin; Zapor, Michael.

Am J Trop Med Hyg ; 89(3): 501-6, 2013 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-23836567

12.

First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers.

Spring, Michele; Murphy, Jittawadee; Nielsen, Robin; Dowler, Megan; Bennett, Jason W; Zarling, Stasya; Williams, Jack; de la Vega, Patricia; Ware, Lisa; Komisar, Jack; Polhemus, Mark; Richie, Thomas L; Epstein, Judy; Tamminga, Cindy; Chuang, Ilin; Richie, Nancy; O'Neil, Michael; Heppner, D Gray; Healer, Julie; O'Neill, Matthew; Smithers, Hannah; Finney, Olivia C; Mikolajczak, Sebastian A; Wang, Ruobing; Cowman, Alan; Ockenhouse, Christian; Krzych, Urszula; Kappe, Stefan H I.

Vaccine ; 31(43): 4975-83, 2013 Oct 09.

Artigo em Inglês | MEDLINE | ID: mdl-24029408

13.

Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled human malaria infection.

Tamminga, Cindy; Sedegah, Martha; Maiolatesi, Santina; Fedders, Charlotte; Reyes, Sharina; Reyes, Anatalio; Vasquez, Carlos; Alcorta, Yolanda; Chuang, Ilin; Spring, Michele; Kavanaugh, Michael; Ganeshan, Harini; Huang, Jun; Belmonte, Maria; Abot, Esteban; Belmonte, Arnel; Banania, Joglenna; Farooq, Fouzia; Murphy, Jittawadee; Komisar, Jack; Richie, Nancy O; Bennett, Jason; Limbach, Keith; Patterson, Noelle B; Bruder, Joseph T; Shi, Meng; Miller, Edward; Dutta, Sheetij; Diggs, Carter; Soisson, Lorraine A; Hollingdale, Michael R; Epstein, Judith E; Richie, Thomas L.

Hum Vaccin Immunother ; 9(10): 2165-77, 2013 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-23899517

14.

DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity.

Chuang, Ilin; Sedegah, Martha; Cicatelli, Susan; Spring, Michele; Polhemus, Mark; Tamminga, Cindy; Patterson, Noelle; Guerrero, Melanie; Bennett, Jason W; McGrath, Shannon; Ganeshan, Harini; Belmonte, Maria; Farooq, Fouzia; Abot, Esteban; Banania, Jo Glenna; Huang, Jun; Newcomer, Rhonda; Rein, Lisa; Litilit, Dianne; Richie, Nancy O; Wood, Chloe; Murphy, Jittawadee; Sauerwein, Robert; Hermsen, Cornelus C; McCoy, Andrea J; Kamau, Edwin; Cummings, James; Komisar, Jack; Sutamihardja, Awalludin; Shi, Meng; Epstein, Judith E; Maiolatesi, Santina; Tosh, Donna; Limbach, Keith; Angov, Evelina; Bergmann-Leitner, Elke; Bruder, Joseph T; Doolan, Denise L; King, C Richter; Carucci, Daniel; Dutta, Sheetij; Soisson, Lorraine; Diggs, Carter; Hollingdale, Michael R; Ockenhouse, Christian F; Richie, Thomas L.

PLoS One ; 8(2): e55571, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23457473

15.

A consultation on the optimization of controlled human malaria infection by mosquito bite for evaluation of candidate malaria vaccines.

Laurens, Matthew B; Duncan, Christopher J; Epstein, Judith E; Hill, Adrian V; Komisar, Jack L; Lyke, Kirsten E; Ockenhouse, Christian F; Richie, Thomas L; Roestenberg, Meta; Sauerwein, Robert W; Spring, Michele D; Talley, Angela K; Moorthy, Vasee S.

Vaccine ; 30(36): 5302-4, 2012 Aug 03.

Artigo em Inglês | MEDLINE | ID: mdl-22659449

16.

Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP component.

Tamminga, Cindy; Sedegah, Martha; Regis, David; Chuang, Ilin; Epstein, Judith E; Spring, Michele; Mendoza-Silveiras, Jose; McGrath, Shannon; Maiolatesi, Santina; Reyes, Sharina; Steinbeiss, Victoria; Fedders, Charlotte; Smith, Kathryn; House, Brent; Ganeshan, Harini; Lejano, Jennylynn; Abot, Esteban; Banania, Glenna J; Sayo, Renato; Farooq, Fouzia; Belmonte, Maria; Murphy, Jittawadee; Komisar, Jack; Williams, Jackie; Shi, Meng; Brambilla, Donald; Manohar, Nalini; Richie, Nancy O; Wood, Chloe; Limbach, Keith; Patterson, Noelle B; Bruder, Joseph T; Doolan, Denise L; King, C Richter; Diggs, Carter; Soisson, Lorraine; Carucci, Daniel; Levine, Gail; Dutta, Sheetij; Hollingdale, Michael R; Ockenhouse, Christian F; Richie, Thomas L.

PLoS One ; 6(10): e25868, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-22003411

17.

High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model.

Dutta, Sheetij; Sullivan, JoAnn S; Grady, Katharine K; Haynes, J David; Komisar, Jack; Batchelor, Adrian H; Soisson, Lorraine; Diggs, Carter L; Heppner, D Gray; Lanar, David E; Collins, William E; Barnwell, John W.

PLoS One ; 4(12): e8138, 2009 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-19997632

18.

Adenovirus 5 and 35 vectors expressing Plasmodium falciparum circumsporozoite surface protein elicit potent antigen-specific cellular IFN-gamma and antibody responses in mice.

Shott, Joseph P; McGrath, Shannon M; Pau, Maria Grazia; Custers, Jerome H V; Ophorst, Olga; Demoitié, Marie-Ange; Dubois, Marie-Claude; Komisar, Jack; Cobb, Michelle; Kester, Kent E; Dubois, Patrice; Cohen, Joe; Goudsmit, Jaap; Heppner, D Gray; Stewart, V Ann.

Vaccine ; 26(23): 2818-23, 2008 Jun 02.

Artigo em Inglês | MEDLINE | ID: mdl-18455276

19.

Murine lethal toxic shock caused by intranasal administration of staphylococcal enterotoxin B.

Savransky, Vladimir; Rostapshov, Victor; Pinelis, Dmitriy; Polotsky, Yury; Korolev, Sergey; Komisar, Jack; Fegeding, Konstantin.

Toxicol Pathol ; 31(4): 373-8, 2003.

Artigo em Inglês | MEDLINE | ID: mdl-12851102

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