RESUMO
Forty HIV-positive women living with HIV-infected sexual partner as well as 40 HIV-positive women from discordant pairs (HIV-positive wife and HIV-negative husband) were surveyed. Less than half of HIV-infected patients (40%) specified the use of condoms for sexual contacts. In the group of women living with HIV-infected partner more expressed immunosupression (CD4 count 427 cells/mcl versus 528 cells/mcl) was observed. Statistically significant increased viral load in the 1st group compared with the women from discordant pairs was revealed.
Assuntos
Infecções por HIV/epidemiologia , Infecções por HIV/imunologia , Tolerância Imunológica , Adulto , Contagem de Linfócito CD4 , Feminino , Infecções por HIV/complicações , Infecções por HIV/virologia , Humanos , Masculino , Federação Russa/epidemiologia , Sexo Seguro/estatística & dados numéricos , Parceiros Sexuais , População Urbana , Carga ViralRESUMO
An experimental model of associated influenza-parainfluenza infection has been developed. Simultaneous inoculation of mice with influenza A2/21/65 and parainfluenza type 3 or inoculation with these viruses at an interval of 24 hours was shown to produce a considerably more severe disease as manifested by the development of severe confluent pneumonias involving both lungs and death of the inoculated animals. The animals with the associated infection showed no significant difference in antibody titers or the intensity of immunity as compared with control groups (influenza or parainfluenza monoinfection). The development of the mixed infection was accompanied by the inhibition of neutrophilic and macrophage phagocytosis and inhibition of interferon production.