Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Human retinoic acid-regulated CD161⁺ regulatory T cells support wound repair in intestinal mucosa.

Povoleri, Giovanni A M; Nova-Lamperti, Estefania; Scottà, Cristiano; Fanelli, Giorgia; Chen, Yun-Ching; Becker, Pablo D; Boardman, Dominic; Costantini, Benedetta; Romano, Marco; Pavlidis, Polychronis; McGregor, Reuben; Pantazi, Eirini; Chauss, Daniel; Sun, Hong-Wei; Shih, Han-Yu; Cousins, David J; Cooper, Nichola; Powell, Nick; Kemper, Claudia; Pirooznia, Mehdi; Laurence, Arian; Kordasti, Shahram; Kazemian, Majid; Lombardi, Giovanna; Afzali, Behdad.

Nat Immunol ; 19(12): 1403-1414, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30397350

2.

A quantitative evaluation of the impact of vaccine roll-out rate and coverage on reducing deaths: insights from the first 2 years of COVID-19 epidemic in Iran.

Ghafari, Mahan; Hosseinpour, Sepanta; Rezaee-Zavareh, Mohammad Saeid; Dascalu, Stefan; Rostamian, Somayeh; Aramesh, Kiarash; Madani, Kaveh; Kordasti, Shahram.

BMC Med ; 21(1): 429, 2023 11 13.

Artigo em Inglês | MEDLINE | ID: mdl-37953291

3.

Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells.

Daher, May; Basar, Rafet; Gokdemir, Elif; Baran, Natalia; Uprety, Nadima; Nunez Cortes, Ana Karen; Mendt, Mayela; Kerbauy, Lucila Nassif; Banerjee, Pinaki P; Shanley, Mayra; Imahashi, Nobuhiko; Li, Li; Lim, Francesca Lorraine Wei Inng; Fathi, Mohsen; Rezvan, Ali; Mohanty, Vakul; Shen, Yifei; Shaim, Hila; Lu, Junjun; Ozcan, Gonca; Ensley, Emily; Kaplan, Mecit; Nandivada, Vandana; Bdiwi, Mustafa; Acharya, Sunil; Xi, Yuanxin; Wan, Xinhai; Mak, Duncan; Liu, Enli; Jiang, Xin Ru; Ang, Sonny; Muniz-Feliciano, Luis; Li, Ye; Wang, Jing; Kordasti, Shahram; Petrov, Nedyalko; Varadarajan, Navin; Marin, David; Brunetti, Lorenzo; Skinner, Richard J; Lyu, Shangrong; Silva, Leiser; Turk, Rolf; Schubert, Mollie S; Rettig, Garrett R; McNeill, Matthew S; Kurgan, Gavin; Behlke, Mark A; Li, Heng; Fowlkes, Natalie W.

Blood ; 137(5): 624-636, 2021 02 04.

Artigo em Inglês | MEDLINE | ID: mdl-32902645

4.

Differential inhibition of T-cell receptor and STAT5 signaling pathways determines the immunomodulatory effects of dasatinib in chronic phase chronic myeloid leukemia.

Harrington, Patrick; Dillon, Richard; Radia, Deepti; Rousselot, Philippe; McLornan, Donal P; Ong, Mark; Green, Anna; Verde, Alessandro; Hussain, Farzana; Raj, Kavita; Kordasti, Shahram; Harrison, Claire; De Lavallade, Hugues.

Haematologica ; 108(6): 1555-1566, 2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-36700403

5.

Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells.

Couch, Amalie C M; Solomon, Shiden; Duarte, Rodrigo R R; Marrocu, Alessia; Sun, Yiqing; Sichlinger, Laura; Matuleviciute, Rugile; Polit, Lucia Dutan; Hanger, Bjørn; Brown, Amelia; Kordasti, Shahram; Srivastava, Deepak P; Vernon, Anthony C.

Brain Behav Immun ; 110: 43-59, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-36781081

6.

Chronic myeloid leukaemia patients at diagnosis and resistant to tyrosine kinase inhibitor therapy display exhausted T-cell phenotype.

Harrington, Patrick; Dillon, Richard; Radia, Deepti; McLornan, Donal; Woodley, Claire; Asirvatham, Susan; Raj, Kavita; Curto-Garcia, Natalia; Saunders, Jamie; Kordasti, Shahram; Harrison, Claire; de Lavallade, Hugues.

Br J Haematol ; 198(6): 1011-1015, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35802024

7.

Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction.

Lim, Shok Ping; Costantini, Benedetta; Mian, Syed A; Perez Abellan, Pilar; Gandhi, Shreyans; Martinez Llordella, Marc; Lozano, Juan Jose; Antunes Dos Reis, Rita; Povoleri, Giovanni A M; Mourikis, Thanos P; Abarrategi, Ander; Ariza-McNaughton, Linda; Heck, Susanne; Irish, Jonathan M; Lombardi, Giovanna; Marsh, Judith C W; Bonnet, Dominique; Kordasti, Shahram; Mufti, Ghulam J.

Blood ; 136(7): 885-897, 2020 08 13.

Artigo em Inglês | MEDLINE | ID: mdl-32294156

8.

Reduced frequencies and functional impairment of dendritic cell subsets and non-classical monocytes in myelodysplastic syndromes.

Van Leeuwen-Kerkhoff, Nathalie; Westers, Theresia M; Poddighe, Pino J; Povoleri, Giovanni A M; Timms, Jessica A; Kordasti, Shahram; De Gruijl, Tanja D; Van de Loosdrecht, Arjan A.

Haematologica ; 107(3): 655-667, 2022 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-33567812

9.

Risk of COVID-19 death in cancer patients: an analysis from Guy's Cancer Centre and King's College Hospital in London.

Russell, Beth; Moss, Charlotte L; Shah, Vallari; Ko, Thinzar Ko; Palmer, Kieran; Sylva, Rushan; George, Gincy; Monroy-Iglesias, Maria J; Patten, Piers; Ceesay, Muhammed Mansour; Benjamin, Reuben; Potter, Victoria; Pagliuca, Antonio; Papa, Sophie; Irshad, Sheeba; Ross, Paul; Spicer, James; Kordasti, Shahram; Crawley, Danielle; Wylie, Harriet; Cahill, Fidelma; Haire, Anna; Zaki, Kamarul; Sita-Lumsden, Ailsa; Josephs, Debra; Enting, Deborah; Swampillai, Angela; Sawyer, Elinor; D'Souza, Andrea; Gomberg, Simon; Harrison, Claire; Fields, Paul; Wrench, David; Rigg, Anne; Sullivan, Richard; Kulasekararaj, Austin; Dolly, Saoirse; Van Hemelrijck, Mieke.

Br J Cancer ; 125(7): 939-947, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34400804

10.

Clinicopathological characterisation of myeloproliferative neoplasm-unclassifiable (MPN-U): a retrospective analysis from a large UK tertiary referral centre.

Deschamps, Paul; Moonim, Mufaddal; Radia, Deepti; Curto-Garcia, Natalia; Woodley, Claire; Bassiony, Sarah; O'Sullivan, Jennifer; Harrington, Patrick; Raj, Kavita; Francis, Yvonne; Kordasti, Shahram; Ali, Sahra; Harrison, Claire N; McLornan, Donal P.

Br J Haematol ; 193(4): 792-797, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33751548

11.

Altered immune response to the annual influenza A vaccine in patients with myeloproliferative neoplasms.

Alimam, Samah; Ann Timms, Jessica; Harrison, Claire N; Dillon, Richard; Mare, Tracey; DeLavallade, Hugues; Radia, Deepti; Woodley, Claire; Francis, Yvonne; Sanchez, Katy; Kordasti, Shahram; McLornan, Donal P.

Br J Haematol ; 193(1): 150-154, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33159465

12.

Single dose of BNT162b2 mRNA vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) induces neutralising antibody and polyfunctional T-cell responses in patients with chronic myeloid leukaemia.

Harrington, Patrick; Doores, Katie J; Radia, Deepti; O'Reilly, Amy; Lam, Ho Pui Jeff; Seow, Jeffrey; Graham, Carl; Lechmere, Thomas; McLornan, Donal; Dillon, Richard; Shanmugharaj, Yogita; Espehana, Andreas; Woodley, Claire; Saunders, Jamie; Curto-Garcia, Natalia; O'Sullivan, Jennifer; Raj, Kavita; Kordasti, Shahram; Malim, Michael H; Harrison, Claire; de Lavallade, Hugues.

Br J Haematol ; 194(6): 999-1006, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34085278

13.

Anti-TNF treatment negatively regulates human CD4⁺ T-cell activation and maturation in vitro, but does not confer an anergic or suppressive phenotype.

Povoleri, Giovanni A M; Lalnunhlimi, Sylvine; Steel, Kathryn J A; Agrawal, Shweta; O'Byrne, Aoife M; Ridley, Michael; Kordasti, Shahram; Frederiksen, Klaus S; Roberts, Ceri A; Taams, Leonie S.

Eur J Immunol ; 50(3): 445-458, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31722123

14.

Applicability, safety, and biological activity of regulatory T cell therapy in liver transplantation.

Sánchez-Fueyo, Alberto; Whitehouse, Gavin; Grageda, Nathali; Cramp, Matthew E; Lim, Tiong Y; Romano, Marco; Thirkell, Sarah; Lowe, Katie; Fry, Laura; Heward, Julie; Kerr, Alex; Ali, Jakia; Fisher, Chris; Lewis, Gillian; Hope, Andrew; Kodela, Elisavet; Lyne, Mike; Farzaneh, Farzin; Kordasti, Shahram; Rebollo-Mesa, Irene; Jose Lozano, Juan; Safinia, Niloufar; Heaton, Nigel; Lechler, Robert; Martínez-Llordella, Marc; Lombardi, Giovanna.

Am J Transplant ; 20(4): 1125-1136, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-31715056

15.

Thrombomodulin-expressing monocytes are associated with low-risk features in myelodysplastic syndromes and dampen excessive immune activation.

van Leeuwen-Kerkhoff, Nathalie; Westers, Theresia M; Poddighe, Pino J; de Gruijl, Tanja D; Kordasti, Shahram; van de Loosdrecht, Arjan A.

Haematologica ; 105(4): 961-971, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-31273091

16.

Essential thrombocythaemia treated with recombinant interferon: 'real world' United Kingdom referral centre experience.

Desterro, Joana; McLornan, Donal P; Curto Garcia, Natalia; O'Sullivan, Jennifer; Alimam, Samah; Keohane, Clodagh; Woodley, Claire; Francis, Yvonne; Kordasti, Shahram; Radia, Deepti H; Harrison, Claire N.

Br J Haematol ; 186(4): 561-564, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-31090926

17.

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment.

Kordasti, Shahram; Costantini, Benedetta; Seidl, Thomas; Perez Abellan, Pilar; Martinez Llordella, Marc; McLornan, Donal; Diggins, Kirsten E; Kulasekararaj, Austin; Benfatto, Cinzia; Feng, Xingmin; Smith, Alexander; Mian, Syed A; Melchiotti, Rossella; de Rinaldis, Emanuele; Ellis, Richard; Petrov, Nedyalko; Povoleri, Giovanni A M; Chung, Sun Sook; Thomas, N Shaun B; Farzaneh, Farzin; Irish, Jonathan M; Heck, Susanne; Young, Neal S; Marsh, Judith C W; Mufti, Ghulam J.

Blood ; 128(9): 1193-205, 2016 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-27281795

18.

Cluster stability in the analysis of mass cytometry data.

Melchiotti, Rossella; Gracio, Filipe; Kordasti, Shahram; Todd, Alan K; de Rinaldis, Emanuele.

Cytometry A ; 91(1): 73-84, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27754590

19.

Natural born survivors: the inglorious TP53.

Platzbecker, Uwe; Kordasti, Shahram.

Blood ; 136(24): 2727-2728, 2020 12 10.

Artigo em Inglês | MEDLINE | ID: mdl-33301036

20.

Evidence of robust memory T-cell responses in patients with chronic myeloproliferative neoplasms following infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

Harrington, Patrick; Harrison, Claire N; Dillon, Richard; Radia, Deepti H; Rezvani, Katayoun; Raj, Kavita; Woodley, Claire; Curto-Garcia, Natalia; O'Sullivan, Jennifer; Saunders, Jamie; Kordasti, Shahram; Ali, Sahra; de Lavallade, Hugues; McLornan, Donal P.

Br J Haematol ; 193(4): 692-696, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33719038

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