Detalhe da pesquisa
1.
In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells.
Blood
; 121(8): 1255-64, 2013 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23212524
2.
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.
Nat Genet
; 38(5): 518-20, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16604072
3.
Repeats, longevity and the sources of mtDNA deletions: evidence from 'deletional spectra'.
Trends Genet
; 26(8): 340-3, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20591530
4.
Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis.
Acta Neuropathol
; 124(2): 209-20, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22688405
5.
Mitochondrial Pseudogenes Suggest Repeated Inter-Species Hybridization among Direct Human Ancestors.
Genes (Basel)
; 13(5)2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35627195
6.
Mitochondrial DNA deletions in mice in men: substantia nigra is much less affected in the mouse.
Biochim Biophys Acta
; 1797(6-7): 1159-62, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20388490
7.
Collection of isolated cells for studying mitochondrial DNA mutations within individual cells.
Methods Mol Biol
; 554: 315-27, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19513683
8.
Quantitative analysis of somatic mitochondrial DNA mutations by single-cell single-molecule PCR.
Methods Mol Biol
; 554: 329-69, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19513684
9.
Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging?
Aging Cell
; 5(3): 279-82, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16842501
10.
Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis.
Curr Opin Genet Dev
; 38: 127-132, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27497229
11.
Quantitation of Mitochondrial DNA Deletions Via Restriction Digestion/Long-Range Single-Molecule PCR.
Methods Mol Biol
; 1351: 33-46, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26530673
12.
Therapeutic potential of targeting microRNA-10b in established intracranial glioblastoma: first steps toward the clinic.
EMBO Mol Med
; 8(3): 268-87, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26881967
13.
mtLOH (mitochondrial loss of heteroplasmy), aging, and 'surrogate self'.
Mech Ageing Dev
; 123(8): 891-8, 2002 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-12044937
14.
Mutation and intracellular clonal expansion of mitochondrial genomes: two synergistic components of the aging process?
Mech Ageing Dev
; 124(1): 49-53, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12618006
15.
Where and when do somatic mtDNA mutations occur?
Ann N Y Acad Sci
; 1019: 240-4, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15247022
16.
Clonal expansions of mitochondrial genomes: implications for in vivo mutational spectra.
Mutat Res
; 522(1-2): 13-9, 2003 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-12517407
17.
When man got his mtDNA deletions?
Aging Cell
; 13(4): 579-82, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24894296
18.
ERRATUM TO: Quantitation of Mitochondrial DNA Deletions Via Restriction Digestion/Long-Range Single-Molecule PCR.
Methods Mol Biol
; 1351: E1, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26810329
19.
On the timing and the extent of clonal expansion of mtDNA deletions: evidence from single-molecule PCR.
Exp Neurol
; 218(2): 316-9, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19426731
20.
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
Aging Cell
; 8(4): 502-6, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19416127