Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

A weight of evidence review of the genotoxicity of titanium dioxide (TiO₂).

Kirkland, David; Aardema, Marilyn J; Battersby, Rüdiger V; Beevers, Carol; Burnett, Karin; Burzlaff, Arne; Czich, Andreas; Donner, E Maria; Fowler, Paul; Johnston, Helinor J; Krug, Harald F; Pfuhler, Stefan; Stankowski, Leon F.

Regul Toxicol Pharmacol ; 136: 105263, 2022 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-36228836

2.

Non-Animal Strategies for Toxicity Assessment of Nanoscale Materials: Role of Adverse Outcome Pathways in the Selection of Endpoints.

Halappanavar, Sabina; Nymark, Penny; Krug, Harald F; Clift, Martin J D; Rothen-Rutishauser, Barbara; Vogel, Ulla.

Small ; 17(15): e2007628, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33559363

3.

Cause-and-Effect Analysis as a Tool To Improve the Reproducibility of Nanobioassays: Four Case Studies.

Petersen, Elijah J; Hirsch, Cordula; Elliott, John T; Krug, Harald F; Aengenheister, Leonie; Arif, Ali Talib; Bogni, Alessia; Kinsner-Ovaskainen, Agnieszka; May, Sarah; Walser, Tobias; Wick, Peter; Roesslein, Matthias.

Chem Res Toxicol ; 33(5): 1039-1054, 2020 05 18.

Artigo em Inglês | MEDLINE | ID: mdl-31507156

4.

Uptake of label-free graphene oxide by Caco-2 cells is dependent on the cell differentiation status.

Kucki, Melanie; Diener, Liliane; Bohmer, Nils; Hirsch, Cordula; Krug, Harald F; Palermo, Vincenzo; Wick, Peter.

J Nanobiotechnology ; 15(1): 46, 2017 Jun 21.

Artigo em Inglês | MEDLINE | ID: mdl-28637475

5.

Use of Cause-and-Effect Analysis to Design a High-Quality Nanocytotoxicology Assay.

Rösslein, Matthias; Elliott, John T; Salit, Marc; Petersen, Elijah J; Hirsch, Cordula; Krug, Harald F; Wick, Peter.

Chem Res Toxicol ; 28(1): 21-30, 2015 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-25473822

6.

Transfer studies of polystyrene nanoparticles in the ex vivo human placenta perfusion model: key sources of artifacts.

Grafmueller, Stefanie; Manser, Pius; Diener, Liliane; Maurizi, Lionel; Diener, Pierre-André; Hofmann, Heinrich; Jochum, Wolfram; Krug, Harald F; Buerki-Thurnherr, Tina; von Mandach, Ursula; Wick, Peter.

Sci Technol Adv Mater ; 16(4): 044602, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-27877820

7.

Toward the development of decision supporting tools that can be used for safe production and use of nanomaterials.

Som, Claudia; Nowack, Bernd; Krug, Harald F; Wick, Peter.

Acc Chem Res ; 46(3): 863-72, 2013 Mar 19.

Artigo em Inglês | MEDLINE | ID: mdl-23110540

8.

Nanosafety research--are we on the right track?

Krug, Harald F.

Angew Chem Int Ed Engl ; 53(46): 12304-19, 2014 Nov 10.

Artigo em Inglês | MEDLINE | ID: mdl-25302857

9.

Classification framework for graphene-based materials.

Wick, Peter; Louw-Gaume, Anna E; Kucki, Melanie; Krug, Harald F; Kostarelos, Kostas; Fadeel, Bengt; Dawson, Kenneth A; Salvati, Anna; Vázquez, Ester; Ballerini, Laura; Tretiach, Mauro; Benfenati, Fabio; Flahaut, Emmanuel; Gauthier, Laury; Prato, Maurizio; Bianco, Alberto.

Angew Chem Int Ed Engl ; 53(30): 7714-8, 2014 Jul 21.

Artigo em Inglês | MEDLINE | ID: mdl-24917379

10.

Comparability of in vitro tests for bioactive nanoparticles: a common assay to detect reactive oxygen species as an example.

Roesslein, Matthias; Hirsch, Cordula; Kaiser, Jean-Pierre; Krug, Harald F; Wick, Peter.

Int J Mol Sci ; 14(12): 24320-37, 2013 Dec 13.

Artigo em Inglês | MEDLINE | ID: mdl-24351819

11.

Effects of subtoxic concentrations of TiO2 and ZnO nanoparticles on human lymphocytes, dendritic cells and exosome production.

Andersson-Willman, Britta; Gehrmann, Ulf; Cansu, Zekiye; Buerki-Thurnherr, Tina; Krug, Harald F; Gabrielsson, Susanne; Scheynius, Annika.

Toxicol Appl Pharmacol ; 264(1): 94-103, 2012 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-22842014

12.

Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro.

Gasser, Michael; Wick, Peter; Clift, Martin J D; Blank, Fabian; Diener, Liliane; Yan, Bing; Gehr, Peter; Krug, Harald F; Rothen-Rutishauser, Barbara.

Part Fibre Toxicol ; 9: 17, 2012 May 24.

Artigo em Inglês | MEDLINE | ID: mdl-22624622

13.

Collection of Controlled Nanosafety Data-The CoCoN-Database, a Tool to Assess Nanomaterial Hazard.

Krug, Harald F.

Nanomaterials (Basel) ; 12(3)2022 Jan 28.

Artigo em Inglês | MEDLINE | ID: mdl-35159786

14.

A Systematic Review on the Hazard Assessment of Amorphous Silica Based on the Literature From 2013 to 2018.

Krug, Harald F.

Front Public Health ; 10: 902893, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35784253

15.

120 years of nanosilver history: implications for policy makers.

Nowack, Bernd; Krug, Harald F; Height, Murray.

Environ Sci Technol ; 45(4): 1177-83, 2011 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-21218770

16.

Evidence maps: communicating risk assessments in societal controversies: the case of engineered nanoparticles.

Wiedemann, Peter; Schütz, Holger; Spangenberg, Albena; Krug, Harald F.

Risk Anal ; 31(11): 1770-83, 2011 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22084864

17.

Nanotoxicology: an interdisciplinary challenge.

Krug, Harald F; Wick, Peter.

Angew Chem Int Ed Engl ; 50(6): 1260-78, 2011 Feb 07.

Artigo em Inglês | MEDLINE | ID: mdl-21290492

18.

A methodology for developing key events to advance nanomaterial-relevant adverse outcome pathways to inform risk assessment.

Halappanavar, Sabina; Ede, James D; Mahapatra, Indrani; Krug, Harald F; Kuempel, Eileen D; Lynch, Iseult; Vandebriel, Rob J; Shatkin, Jo Anne.

Nanotoxicology ; 15(3): 289-310, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33317378

19.

The adsorption of biomolecules to multi-walled carbon nanotubes is influenced by both pulmonary surfactant lipids and surface chemistry.

Gasser, Michael; Rothen-Rutishauser, Barbara; Krug, Harald F; Gehr, Peter; Nelle, Mathias; Yan, Bing; Wick, Peter.

J Nanobiotechnology ; 8: 31, 2010 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-21159192

20.

Peptoidic amino- and guanidinium-carrier systems: targeted drug delivery into the cell cytosol or the nucleus.

Schröder, Tina; Niemeier, Nicole; Afonin, Sergii; Ulrich, Anne S; Krug, Harald F; Bräse, Stefan.

J Med Chem ; 51(3): 376-9, 2008 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-18215012

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A weight of evidence review of the genotoxicity of titanium dioxide (TiO₂).

Non-Animal Strategies for Toxicity Assessment of Nanoscale Materials: Role of Adverse Outcome Pathways in the Selection of Endpoints.

Cause-and-Effect Analysis as a Tool To Improve the Reproducibility of Nanobioassays: Four Case Studies.

Uptake of label-free graphene oxide by Caco-2 cells is dependent on the cell differentiation status.

Use of Cause-and-Effect Analysis to Design a High-Quality Nanocytotoxicology Assay.

Transfer studies of polystyrene nanoparticles in the ex vivo human placenta perfusion model: key sources of artifacts.

Toward the development of decision supporting tools that can be used for safe production and use of nanomaterials.

Nanosafety research--are we on the right track?

Classification framework for graphene-based materials.

Comparability of in vitro tests for bioactive nanoparticles: a common assay to detect reactive oxygen species as an example.

Effects of subtoxic concentrations of TiO2 and ZnO nanoparticles on human lymphocytes, dendritic cells and exosome production.

Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro.

Collection of Controlled Nanosafety Data-The CoCoN-Database, a Tool to Assess Nanomaterial Hazard.

A Systematic Review on the Hazard Assessment of Amorphous Silica Based on the Literature From 2013 to 2018.

120 years of nanosilver history: implications for policy makers.

Evidence maps: communicating risk assessments in societal controversies: the case of engineered nanoparticles.

Nanotoxicology: an interdisciplinary challenge.

A methodology for developing key events to advance nanomaterial-relevant adverse outcome pathways to inform risk assessment.

The adsorption of biomolecules to multi-walled carbon nanotubes is influenced by both pulmonary surfactant lipids and surface chemistry.

Peptoidic amino- and guanidinium-carrier systems: targeted drug delivery into the cell cytosol or the nucleus.