Detalhe da pesquisa
1.
Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1.
PLoS Biol
; 21(6): e3002156, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37315086
2.
Crystal structure of Bak bound to the BH3 domain of Bnip5, a noncanonical BH3 domain-containing protein.
Proteins
; 92(1): 44-51, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37553948
3.
Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions.
Cell
; 136(1): 85-96, 2009 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19135891
4.
Eif2b3 mutants recapitulate phenotypes of vanishing white matter disease and validate novel disease alleles in zebrafish.
Hum Mol Genet
; 30(5): 331-342, 2021 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33517449
5.
Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1.
Biochem Biophys Res Commun
; 625: 174-180, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35964379
6.
Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus.
PLoS Biol
; 17(7): e3000367, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31323018
7.
The transcription factor PITX1 drives astrocyte differentiation by regulating the SOX9 gene.
J Biol Chem
; 295(39): 13677-13690, 2020 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32759168
8.
Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity.
Bioorg Med Chem
; 26(18): 5204-5211, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249496
9.
Crystal structures of two forms of the Acanthamoeba polyphaga mimivirus Rab GTPase.
Arch Virol
; 162(11): 3407-3416, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28779233
10.
Two-track virtual screening approach to identify both competitive and allosteric inhibitors of human small C-terminal domain phosphatase 1.
J Comput Aided Mol Des
; 31(8): 743-753, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28653253
11.
Crystal structure of SP-PTP, a low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes.
Biochem Biophys Res Commun
; 478(3): 1217-22, 2016 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27545603
12.
High-resolution crystal structure of the PDZ1 domain of human protein tyrosine phosphatase PTP-Bas.
Biochem Biophys Res Commun
; 478(3): 1205-10, 2016 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27544031
13.
Identification of novel protein tyrosine phosphatase sigma inhibitors promoting neurite extension.
Bioorg Med Chem Lett
; 26(1): 87-93, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26602279
14.
Structural analysis of the polo-box domain of human Polo-like kinase 2.
Proteins
; 83(7): 1201-8, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25846005
15.
The family-wide structure and function of human dual-specificity protein phosphatases.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 2): 421-35, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24531476
16.
Structural insights into the dual nucleotide exchange and GDI displacement activity of SidM/DrrA.
EMBO J
; 29(2): 496-504, 2010 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19942850
17.
VipD of Legionella pneumophila targets activated Rab5 and Rab22 to interfere with endosomal trafficking in macrophages.
PLoS Pathog
; 8(12): e1003082, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23271971
18.
Phosphoinositides differentially regulate protrudin localization through the FYVE domain.
J Biol Chem
; 287(49): 41268-76, 2012 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23043110
19.
Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 8): 1587-97, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23897481
20.
Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 8): 1522-9, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23897475