Detalhe da pesquisa
1.
The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity.
Immunity
; 39(4): 647-60, 2013 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24120359
2.
RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events.
J Immunol
; 192(12): 5963-73, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24813206
3.
A coding IRAK2 protein variant compromises Toll-like receptor (TLR) signaling and is associated with colorectal cancer survival.
J Biol Chem
; 289(33): 23123-23131, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24973222
4.
Heterozygous carriage of a dysfunctional Toll-like receptor 9 allele affects CpG oligonucleotide responses in B cells.
J Biol Chem
; 287(29): 24544-53, 2012 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22613717
5.
A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding.
J Immunol
; 186(7): 4213-22, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21383246
6.
Two human MYD88 variants, S34Y and R98C, interfere with MyD88-IRAK4-myddosome assembly.
J Biol Chem
; 286(2): 1341-53, 2011 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20966070
7.
Mutations at the accommodation gate of the ribosome impair RF2-dependent translation termination.
RNA
; 16(9): 1848-53, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20668033
8.
Integrin genes and susceptibility to human melanoma.
Mutagenesis
; 27(3): 367-73, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22189006
9.
MyD88 adaptor-like D96N is a naturally occurring loss-of-function variant of TIRAP.
J Immunol
; 184(6): 3025-32, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20164415
10.
A naturally occurring variant in human TLR9, P99L, is associated with loss of CpG oligonucleotide responsiveness.
J Biol Chem
; 285(47): 36486-94, 2010 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20843814
11.
Identification of an N-terminal recognition site in TLR9 that contributes to CpG-DNA-mediated receptor activation.
J Immunol
; 182(12): 7690-7, 2009 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19494293
12.
Gadd45a is an RNA binding protein and is localized in nuclear speckles.
PLoS One
; 6(1): e14500, 2011 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21249130
13.
Modulation of the CD95-induced apoptosis: the role of CD95 N-glycosylation.
PLoS One
; 6(5): e19927, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21625644
14.
Comprehensive modeling and functional analysis of Toll-like receptor ligand-recognition domains.
Protein Sci
; 19(3): 558-69, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20073080
15.
Study of human RIG-I polymorphisms identifies two variants with an opposite impact on the antiviral immune response.
PLoS One
; 4(10): e7582, 2009 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19859543