Detalhe da pesquisa
1.
A Compendium of Mutational Signatures of Environmental Agents.
Cell
; 177(4): 821-836.e16, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30982602
2.
Tissue Organoid Cultures Metabolize Dietary Carcinogens Proficiently and Are Effective Models for DNA Adduct Formation.
Chem Res Toxicol
; 37(2): 234-247, 2024 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38232180
3.
Metabolic Activation of Benzo[a]pyrene by Human Tissue Organoid Cultures.
Int J Mol Sci
; 24(1)2022 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36614051
4.
Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Arch Toxicol
; 94(12): 4173-4196, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32886187
5.
Nutlin-3a selects for cells harbouring TP53 mutations.
Int J Cancer
; 140(4): 877-887, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27813088
6.
Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism.
Arch Toxicol
; 90(2): 291-304, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25398514
7.
The genome as a record of environmental exposure.
Mutagenesis
; 30(6): 763-70, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26443852
8.
Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved.
Part Fibre Toxicol
; 10: 63, 2013 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24354623
9.
Mutagenicity of N-hydroxy-4-aminobiphenyl in human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Environ Mol Mutagen
; 62(4): 252-264, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33620775
10.
Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Food Chem Toxicol
; 147: 111855, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33189884
11.
Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts.
Methods Protoc
; 2(4)2019 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31766274
12.
Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival.
Cancer Res
; 66(1): 393-403, 2006 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16397254
13.
Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast cancer is associated with poor survival: potential for intervention with 17-allylamino geldanamycin.
Cancer Res
; 64(1): 286-91, 2004 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14729636
14.
TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts.
DNA Repair (Amst)
; 39: 21-33, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26723900
15.
Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours.
Breast Cancer Res
; 7(5): R796-807, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16168126
16.
TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Mutat Res
; 773: 48-62, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25847421
17.
Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts.
Toxicol In Vitro
; 29(1): 34-43, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25230394
18.
Role of IGF-1R in mediating breast cancer invasion and metastasis.
Breast Dis
; 17: 41-7, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-15687676
19.
Metabolic activation of diesel exhaust carcinogens in primary and immortalized human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Environ Mol Mutagen
; 53(3): 207-17, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22351035
20.
Evidence of exposure to aristolochic acid in patients with urothelial cancer from a Balkan endemic nephropathy region of Romania.
Environ Mol Mutagen
; 53(8): 636-41, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22987305