Detalhe da pesquisa
1.
Aldehyde tag coupled with HIPS chemistry enables the production of ADCs conjugated site-specifically to different antibody regions with distinct in vivo efficacy and PK outcomes.
Bioconjug Chem
; 25(7): 1331-41, 2014 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24924618
2.
Hydrazino-Pictet-Spengler ligation as a biocompatible method for the generation of stable protein conjugates.
Bioconjug Chem
; 24(6): 846-51, 2013 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23731037
3.
Shaken, not stirred: collapsing a peptoid monolayer to produce free-floating, stable nanosheets.
J Am Chem Soc
; 133(51): 20808-15, 2011 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21939206
4.
Palladium-catalyzed insertion of alpha-diazoesters into vinyl halides to generate alpha,beta-unsaturated gamma-amino esters.
Angew Chem Int Ed Engl
; 48(20): 3677-80, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19353613
5.
CAT-02-106, a Site-Specifically Conjugated Anti-CD22 Antibody Bearing an MDR1-Resistant Maytansine Payload Yields Excellent Efficacy and Safety in Preclinical Models.
Mol Cancer Ther
; 17(1): 161-168, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29142069
6.
Site-Specific Tandem Knoevenagel Condensation-Michael Addition To Generate Antibody-Drug Conjugates.
ACS Med Chem Lett
; 7(11): 994-998, 2016 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27882197
7.
Generating site-specifically modified proteins via a versatile and stable nucleophilic carbon ligation.
Chem Biol
; 22(2): 293-8, 2015 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25619935
8.
Exploring the effects of linker composition on site-specifically modified antibody-drug conjugates.
Eur J Med Chem
; 88: 3-9, 2014 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25176286
9.
Ionization of dimethyluracil dimers leads to facile proton transfer in the absence of hydrogen bonds.
Nat Chem
; 4(4): 323-9, 2012 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22437719
10.
Folding of a single-chain, information-rich polypeptoid sequence into a highly ordered nanosheet.
Biopolymers
; 96(5): 586-95, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22180906
11.
Cyclization reactions involving palladium-catalyzed carbene insertion into aryl halides.
J Org Chem
; 73(9): 3585-8, 2008 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18370420
12.
Solid-phase synthesis of nucleoside analogues.
J Comb Chem
; 5(3): 292-310, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12739947