Detalhe da pesquisa
1.
Manganese uptake by MtsABC contributes to the pathogenesis of human pathogen group A streptococcus by resisting host nutritional immune defenses.
Infect Immun
; : e0007724, 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38869295
2.
Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence.
Nucleic Acids Res
; 47(14): 7476-7493, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31188450
3.
Group A Streptococcus AdcR Regulon Participates in Bacterial Defense against Host-Mediated Zinc Sequestration and Contributes to Virulence.
Infect Immun
; 88(8)2020 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393509
4.
Phosphatase activity of the control of virulence sensor kinase CovS is critical for the pathogenesis of group A streptococcus.
PLoS Pathog
; 14(10): e1007354, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30379939
5.
Leaderless secreted peptide signaling molecule alters global gene expression and increases virulence of a human bacterial pathogen.
Proc Natl Acad Sci U S A
; 114(40): E8498-E8507, 2017 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923955
6.
Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae.
J Bacteriol
; 201(20)2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31331979
7.
Signaling by a Conserved Quorum Sensing Pathway Contributes to Growth Ex Vivo and Oropharyngeal Colonization of Human Pathogen Group A Streptococcus.
Infect Immun
; 86(5)2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29531135
8.
Multimerization of the Virulence-Enhancing Group A Streptococcus Transcription Factor RivR Is Required for Regulatory Activity.
J Bacteriol
; 199(1)2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27795318
9.
Iron Efflux by PmtA Is Critical for Oxidative Stress Resistance and Contributes Significantly to Group A Streptococcus Virulence.
Infect Immun
; 85(6)2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28348051
10.
Structural and functional analysis of RopB: a major virulence regulator in Streptococcus pyogenes.
Mol Microbiol
; 99(6): 1119-33, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26714274
11.
Adhesin competence repressor (AdcR) from Streptococcus pyogenes controls adaptive responses to zinc limitation and contributes to virulence.
Nucleic Acids Res
; 43(1): 418-32, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25510500
12.
Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling.
Proc Natl Acad Sci U S A
; 111(24): 8838-43, 2014 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24876273
13.
A naturally occurring single amino acid replacement in multiple gene regulator of group A Streptococcus significantly increases virulence.
Am J Pathol
; 185(2): 462-71, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25476528
14.
Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence.
Nucleic Acids Res
; 47(15): 8333-8334, 2019 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31329935
15.
The FasX Small Regulatory RNA Negatively Regulates the Expression of Two Fibronectin-Binding Proteins in Group A Streptococcus.
J Bacteriol
; 197(23): 3720-30, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26391206
16.
Phosphorylation events in the multiple gene regulator of group A Streptococcus significantly influence global gene expression and virulence.
Infect Immun
; 83(6): 2382-95, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25824840
17.
Crystal structure of peroxide stress regulator from Streptococcus pyogenes provides functional insights into the mechanism of oxidative stress sensing.
J Biol Chem
; 288(25): 18311-24, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23645680
18.
Engineered probiotic overcomes pathogen defences using signal interference and antibiotic production to treat infection in mice.
Nat Microbiol
; 9(2): 502-513, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38228859
19.
Functional consequences of substitution mutations in MepR, a repressor of the Staphylococcus aureus MepA multidrug efflux pump gene.
J Bacteriol
; 195(16): 3651-62, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23749979
20.
Natural variation in the promoter of the gene encoding the Mga regulator alters host-pathogen interactions in group a Streptococcus carrier strains.
Infect Immun
; 81(11): 4128-38, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23980109