Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Multiple Signaling Roles of CD3Îµ and Its Application in CAR-T Cell Therapy.

Wu, Wei; Zhou, Qiuping; Masubuchi, Takeya; Shi, Xiaoshan; Li, Hua; Xu, Xinyi; Huang, Min; Meng, Li; He, Xing; Zhu, Hengyu; Gao, Shuaixin; Zhang, Nan; Jing, Ruirui; Sun, Jie; Wang, Haopeng; Hui, Enfu; Wong, Catherine Chiulan; Xu, Chenqi.

Cell ; 182(4): 855-871.e23, 2020 08 20.

Artigo em Inglês | MEDLINE | ID: mdl-32730808

2.

tRNA-m¹A modification promotes T cell expansion via efficient MYC protein synthesis.

Liu, Yongbo; Zhou, Jing; Li, Xiaoyu; Zhang, Xiaoting; Shi, Jintong; Wang, Xuefei; Li, Hao; Miao, Shan; Chen, Huifang; He, Xiaoxiao; Dong, Liting; Lee, Gap Ryol; Zheng, Junke; Liu, Ru-Juan; Su, Bing; Ye, Youqiong; Flavell, Richard A; Yi, Chengqi; Wu, Yuzhang; Li, Hua-Bing.

Nat Immunol ; 23(10): 1433-1444, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36138184

3.

Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit.

Meade, Nathan; Furey, Colleen; Li, Hua; Verma, Rita; Chai, Qingqing; Rollins, Madeline G; DiGiuseppe, Stephen; Naghavi, Mojgan H; Walsh, Derek.

Cell ; 174(5): 1143-1157.e17, 2018 08 23.

Artigo em Inglês | MEDLINE | ID: mdl-30078703

4.

Prospectively Isolated Tetraspanin⁺ Neoblasts Are Adult Pluripotent Stem Cells Underlying Planaria Regeneration.

Zeng, An; Li, Hua; Guo, Longhua; Gao, Xin; McKinney, Sean; Wang, Yongfu; Yu, Zulin; Park, Jungeun; Semerad, Craig; Ross, Eric; Cheng, Li-Chun; Davies, Erin; Lei, Kai; Wang, Wei; Perera, Anoja; Hall, Kate; Peak, Allison; Box, Andrew; Sánchez Alvarado, Alejandro.

Cell ; 173(7): 1593-1608.e20, 2018 06 14.

Artigo em Inglês | MEDLINE | ID: mdl-29906446

5.

m⁶A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development.

Gao, Yimeng; Vasic, Radovan; Song, Yuanbin; Teng, Rhea; Liu, Chengyang; Gbyli, Rana; Biancon, Giulia; Nelakanti, Raman; Lobben, Kirsten; Kudo, Eriko; Liu, Wei; Ardasheva, Anastasia; Fu, Xiaoying; Wang, Xiaman; Joshi, Poorval; Lee, Veronica; Dura, Burak; Viero, Gabriella; Iwasaki, Akiko; Fan, Rong; Xiao, Andrew; Flavell, Richard A; Li, Hua-Bing; Tebaldi, Toma; Halene, Stephanie.

Immunity ; 52(6): 1007-1021.e8, 2020 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-32497523

6.

Conserved class B GPCR activation by a biased intracellular agonist.

Zhao, Li-Hua; He, Qian; Yuan, Qingning; Gu, Yimin; He, Xinheng; Shan, Hong; Li, Junrui; Wang, Kai; Li, Yang; Hu, Wen; Wu, Kai; Shen, Jianhua; Xu, H Eric.

Nature ; 621(7979): 635-641, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37524305

7.

Plant phytochrome B is an asymmetric dimer with unique signalling potential.

Li, Hua; Burgie, E Sethe; Gannam, Zira T K; Li, Huilin; Vierstra, Richard D.

Nature ; 604(7904): 127-133, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35355010

8.

Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors.

Ma, Shanshan; Shen, Qingya; Zhao, Li-Hua; Mao, Chunyou; Zhou, X Edward; Shen, Dan-Dan; de Waal, Parker W; Bi, Peng; Li, Chuntao; Jiang, Yi; Wang, Ming-Wei; Sexton, Patrick M; Wootten, Denise; Melcher, Karsten; Zhang, Yan; Xu, H Eric.

Mol Cell ; 77(3): 669-680.e4, 2020 02 06.

Artigo em Inglês | MEDLINE | ID: mdl-32004470

9.

Haplotype-resolved 3D chromatin architecture of the hybrid pig.

Lin, Yu; Li, Jing; Gu, Yiren; Jin, Long; Bai, Jingyi; Zhang, Jiaman; Wang, Yujie; Liu, Pengliang; Long, Keren; He, Mengnan; Li, Diyan; Liu, Can; Han, Ziyin; Zhang, Yu; Li, Xiaokai; Zeng, Bo; Lu, Lu; Kong, Fanli; Sun, Ying; Fan, Yongliang; Wang, Xun; Wang, Tao; Jiang, An'an; Ma, Jideng; Shen, Linyuan; Zhu, Li; Jiang, Yanzhi; Tang, Guoqing; Fan, Xiaolan; Liu, Qingyou; Li, Hua; Wang, Jinyong; Chen, Li; Ge, Liangpeng; Li, Xuewei; Tang, Qianzi; Li, Mingzhou.

Genome Res ; 34(2): 310-325, 2024 Mar 20.

Artigo em Inglês | MEDLINE | ID: mdl-38479837

10.

MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche.

Wu, Ningbo; Sun, Hongxiang; Zhao, Xiaoyun; Zhang, Yao; Tan, Jianmei; Qi, Yuanyuan; Wang, Qun; Ng, Melissa; Liu, Zhaoyuan; He, Lingjuan; Niu, Xiaoyin; Chen, Lei; Liu, Zhiduo; Li, Hua-Bing; Zeng, Yi Arial; Roulis, Manolis; Liu, Dou; Cheng, Jinke; Zhou, Bin; Ng, Lai Guan; Zou, Duowu; Ye, Youqiong; Flavell, Richard A; Ginhoux, Florent; Su, Bing.

Nature ; 592(7855): 606-610, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33658717

11.

Structural basis for activation of somatostatin receptor 5 by cyclic neuropeptide agonists.

Li, Jingru; You, Chongzhao; Li, Yang; Li, Changyao; Fan, Wenjia; Chen, Zecai; Hu, Wen; Wu, Kai; Xu, H Eric; Zhao, Li-Hua.

Proc Natl Acad Sci U S A ; 121(26): e2321710121, 2024 Jun 25.

Artigo em Inglês | MEDLINE | ID: mdl-38885377

12.

Ago2/CAV1 interaction potentiates metastasis via controlling Ago2 localization and miRNA action.

Lin, Meng-Chieh; Kuo, Wen-Hung; Chen, Shih-Yin; Hsu, Jing-Ya; Lu, Li-Yu; Wang, Chen-Chi; Chen, Yi-Ju; Tsai, Jia-Shiuan; Li, Hua-Jung.

EMBO Rep ; 25(5): 2441-2478, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38649663

13.

UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F.

Zhou, Weihua; Xu, Jie; Tan, Mingjia; Li, Haomin; Li, Hua; Wei, Wenyi; Sun, Yi.

Mol Cell ; 70(6): 1008-1024.e6, 2018 06 21.

Artigo em Inglês | MEDLINE | ID: mdl-29932898

14.

The giant flexoelectric effect in a luffa plant-based sponge for green devices and energy harvesters.

Jiang, Yudi; Yan, Dongze; Wang, Jianxiang; Shao, Li-Hua; Sharma, Pradeep.

Proc Natl Acad Sci U S A ; 120(40): e2311755120, 2023 Oct 03.

Artigo em Inglês | MEDLINE | ID: mdl-37748078

15.

Human FAM111A inhibits vaccinia virus replication by degrading viral protein I3 and is antagonized by poxvirus host range factor SPI-1.

Zhu, Junda; Gao, Xintao; Li, Yijing; Zhang, Zihui; Xie, Shijie; Ren, Shuning; Li, Yarui; Li, Hua; Niu, Kang; Fu, Shufang; Deng, Yining; Li, Yinü; Moss, Bernard; Wu, Wenxue; Peng, Chen.

Proc Natl Acad Sci U S A ; 120(35): e2304242120, 2023 08 29.

Artigo em Inglês | MEDLINE | ID: mdl-37607234

16.

MSI-XGNN: an explainable GNN computational framework integrating transcription- and methylation-level biomarkers for microsatellite instability detection.

Cao, Yang; Wang, Dan; Wu, Jin; Yao, Zhanxin; Shen, Si; Niu, Chao; Liu, Ying; Zhang, Pengcheng; Wang, Quannian; Wang, Jinhao; Li, Hua; Wei, Xi; Wang, Xinxing; Dong, Qingyang.

Brief Bioinform ; 24(6)2023 09 22.

Artigo em Inglês | MEDLINE | ID: mdl-37833839

17.

INPP5K controls the dynamic structure and signaling of wild-type and mutated, leukemia-associated IL-7 receptors.

Moës, Bastien; Li, Hua; Molina-Ortiz, Patricia; Radermecker, Coraline; Rosu, Adeline; Vande Catsyne, Charles-Andrew; Sayyed, Sufyan Ali; Fontela, João; Duque, Mafalda; Mostafa, Alice; Azzi, Abdelhalim; Barata, João T; Merino, Ramon; Xu, Chenqi; Desmet, Christophe J; Schurmans, Stéphane.

Blood ; 141(14): 1708-1717, 2023 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-36599086

18.

Phytochrome interacting factor regulates stomatal aperture by coordinating red light and abscisic acid.

Li, Qian; Zhou, Luyan; Chen, Yanan; Xiao, Ning; Zhang, Dongping; Zhang, Mengjiao; Wang, Wenguo; Zhang, Changquan; Zhang, Anning; Li, Hua; Chen, Jianmin; Gao, Yong.

Plant Cell ; 34(11): 4293-4312, 2022 10 27.

Artigo em Inglês | MEDLINE | ID: mdl-35929789

19.

Structural basis for heparan sulfate co-polymerase action by the EXT1-2 complex.

Li, Hua; Chapla, Digantkumar; Amos, Robert A; Ramiah, Annapoorani; Moremen, Kelley W; Li, Huilin.

Nat Chem Biol ; 19(5): 565-574, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-36593275

20.

Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing.

Reddy, Divya; Bhattacharya, Saikat; Levy, Michaella; Zhang, Ying; Gogol, Madelaine; Li, Hua; Florens, Laurence; Workman, Jerry L.

EMBO Rep ; 24(1): e55345, 2023 01 09.

Artigo em Inglês | MEDLINE | ID: mdl-36354291

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