Detalhe da pesquisa
1.
Nutlin-3a-aa: Improving the Bioactivity of a p53/MDM2 Interaction Inhibitor by Introducing a Solvent-Exposed Methylene Group.
Chembiochem
; 24(6): e202300006, 2023 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36602436
2.
Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions.
Angew Chem Int Ed Engl
; 59(13): 5235-5241, 2020 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31944488
3.
NMR fragment-based screening for development of the CD44-binding small molecules.
Bioorg Chem
; 82: 284-289, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30396062
4.
Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists.
Beilstein J Org Chem
; 15: 513-520, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30873235
5.
Optimized Inhibitors of MDM2 via an Attempted Protein-Templated Reductive Amination.
ChemMedChem
; 15(4): 370-375, 2020 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31774938
6.
A fluorinated indole-based MDM2 antagonist selectively inhibits the growth of p53wt osteosarcoma cells.
FEBS J
; 286(7): 1360-1374, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30715803
7.
Crystal structure of the FAS1 domain of the hyaluronic acid receptor stabilin-2.
Acta Crystallogr D Struct Biol
; 74(Pt 7): 695-701, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29968679
8.
1,4,5-Trisubstituted Imidazole-Based p53-MDM2/MDMX Antagonists with Aliphatic Linkers for Conjugation with Biological Carriers.
J Med Chem
; 60(10): 4234-4244, 2017 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28482147