Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Integrin αvß3 Limits Cytokine Production by Plasmacytoid Dendritic Cells and Restricts TLR-Driven Autoimmunity.

Lorant, Alina K; Yoshida, Anna E; Gilbertson, Emily A; Chu, Talyn; Stefani, Caroline; Acharya, Mridu; Hamerman, Jessica A; Lacy-Hulbert, Adam.

J Immunol ; 2024 Apr 12.

Artigo em Inglês | MEDLINE | ID: mdl-38607278

2.

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function.

Sokolovska, Anna; Becker, Christine E; Ip, W K Eddie; Rathinam, Vijay A K; Brudner, Matthew; Paquette, Nicholas; Tanne, Antoine; Vanaja, Sivapriya K; Moore, Kathryn J; Fitzgerald, Katherine A; Lacy-Hulbert, Adam; Stuart, Lynda M.

Nat Immunol ; 14(6): 543-53, 2013 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-23644505

3.

Inflammation-induced interstitial migration of effector CD4âº T cells is dependent on integrin αV.

Overstreet, Michael G; Gaylo, Alison; Angermann, Bastian R; Hughson, Angela; Hyun, Young-Min; Lambert, Kris; Acharya, Mridu; Billroth-Maclurg, Alison C; Rosenberg, Alexander F; Topham, David J; Yagita, Hideo; Kim, Minsoo; Lacy-Hulbert, Adam; Meier-Schellersheim, Martin; Fowell, Deborah J.

Nat Immunol ; 14(9): 949-58, 2013 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-23933892

4.

The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques.

van Gils, Janine M; Derby, Merran C; Fernandes, Luciana R; Ramkhelawon, Bhama; Ray, Tathagat D; Rayner, Katey J; Parathath, Sajesh; Distel, Emilie; Feig, Jessica L; Alvarez-Leite, Jacqueline I; Rayner, Alistair J; McDonald, Thomas O; O'Brien, Kevin D; Stuart, Lynda M; Fisher, Edward A; Lacy-Hulbert, Adam; Moore, Kathryn J.

Nat Immunol ; 13(2): 136-43, 2012 Jan 08.

Artigo em Inglês | MEDLINE | ID: mdl-22231519

5.

Rhinovirus infection of the airway epithelium enhances mast cell immune responses via epithelial-derived interferons.

Murphy, Ryan C; Lai, Ying; Altman, Matthew C; Barrow, Kaitlyn A; Dill-McFarland, Kimberly A; Liu, Matthew; Hamerman, Jessica A; Lacy-Hulbert, Adam; Piliponsky, Adrian M; Ziegler, Steven F; Altemeier, William A; Debley, Jason S; Gharib, Sina A; Hallstrand, Teal S.

J Allergy Clin Immunol ; 151(6): 1484-1493, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-36708815

6.

Severe acute pancreatitis exhibits distinct cytokine signatures and trajectories in humans: a prospective observational study.

Greer, Phil J; Lee, Peter J; Paragomi, Pedram; Stello, Kim; Phillips, Anna; Hart, Phil; Speake, Cate; Lacy-Hulbert, Adam; Whitcomb, David C; Papachristou, Georgios I.

Am J Physiol Gastrointest Liver Physiol ; 323(5): G428-G438, 2022 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-36098405

7.

De-Mst-ifying microbicidal killing.

Stuart, Lynda M; Lacy-Hulbert, Adam.

Nat Immunol ; 16(11): 1107-8, 2015 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-26482969

8.

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.

Stewart, Cameron R; Stuart, Lynda M; Wilkinson, Kim; van Gils, Janine M; Deng, Jiusheng; Halle, Annett; Rayner, Katey J; Boyer, Laurent; Zhong, Ruiqin; Frazier, William A; Lacy-Hulbert, Adam; El Khoury, Joseph; Golenbock, Douglas T; Moore, Kathryn J.

Nat Immunol ; 11(2): 155-61, 2010 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-20037584

9.

B Cell αv Integrins Regulate TLR-Driven Autoimmunity.

Acharya, Mridu; Raso, Fiona; Sagadiev, Sara; Gilbertson, Emily; Kadavy, Lauren; Li, Quan Z; Yan, Mei; Stuart, Lynda M; Hamerman, Jessica A; Lacy-Hulbert, Adam.

J Immunol ; 205(7): 1810-1818, 2020 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-32859730

10.

Pivotal role for α_V integrins in sustained Tfh support of the germinal center response for long-lived plasma cell generation.

Schrock, Dillon C; Leddon, Scott A; Hughson, Angela; Miller, Jim; Lacy-Hulbert, Adam; Fowell, Deborah J.

Proc Natl Acad Sci U S A ; 116(10): 4462-4470, 2019 03 05.

Artigo em Inglês | MEDLINE | ID: mdl-30770452

11.

Apoptotic Cell-Directed Resolution of Lung Inflammation Requires Myeloid αv Integrin-Mediated Induction of Regulatory T Lymphocytes.

Zhang, Ailiang; Lacy-Hulbert, Adam; Anderton, Stephen; Haslett, Christopher; Savill, John.

Am J Pathol ; 190(6): 1224-1235, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32201264

12.

Penetration resistance: PKR's other talent.

Lacy-Hulbert, Adam; Stuart, Lynda M.

Immunity ; 36(5): 695-6, 2012 May 25.

Artigo em Inglês | MEDLINE | ID: mdl-22633454

13.

Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway.

Boyer, Laurent; Magoc, Lorin; Dejardin, Stephanie; Cappillino, Michael; Paquette, Nicholas; Hinault, Charlotte; Charriere, Guillaume M; Ip, W K Eddie; Fracchia, Shannon; Hennessy, Elizabeth; Erturk-Hasdemir, Deniz; Reichhart, Jean-Marc; Silverman, Neal; Lacy-Hulbert, Adam; Stuart, Lynda M.

Immunity ; 35(4): 536-49, 2011 Oct 28.

Artigo em Inglês | MEDLINE | ID: mdl-22018470

14.

Identification of mast cell progenitor cells in the airways of individuals with allergic asthma.

Murphy, Ryan C; Chow, Yu-Hua; Lai, Ying; Al-Shaikhly, Taha; Petroni, Daniel H; Black, Michele; Hamerman, Jessica A; Lacy-Hulbert, Adam; Piliponsky, Adrian M; Hallstrand, Teal S.

Allergy ; 78(2): 547-549, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36038252

15.

ß8 Integrin Expression and Activation of TGF-ß by Intestinal Dendritic Cells Are Determined by Both Tissue Microenvironment and Cell Lineage.

Boucard-Jourdin, Mathilde; Kugler, David; Endale Ahanda, Marie-Laure; This, Sébastien; De Calisto, Jaime; Zhang, Ailiang; Mora, J Rodrigo; Stuart, Lynda M; Savill, John; Lacy-Hulbert, Adam; Paidassi, Helena.

J Immunol ; 197(5): 1968-78, 2016 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-27481847

16.

A New Expansion Microscopy Method Optimized for Microbiology.

Cheng, Zhangyu; Stefani, Caroline; Skillman, Thomas; Klimas, Aleksandra; Lee, Aramchan; DiBernardo, Emma F; Brown, Karina M; Milman, Tatyana; Gallagher, Brendan R; Lagree, Katherine; Jena, Bhanu P; Pulido, Jose; Mitchell, Aaron P; Filler, Scott G; Hiller, Luisa; Lacy-Hulbert, Adam; Zhao, Yongxin.

Microsc Microanal ; 29(29 Suppl 1): 994, 2023 Jul 22.

Artigo em Inglês | MEDLINE | ID: mdl-37613535

17.

Effects of Asthma and Human Rhinovirus A16 on the Expression of SARS-CoV-2 Entry Factors in Human Airway Epithelium.

Murphy, Ryan C; Lai, Ying; Barrow, Kaitlyn A; Hamerman, Jessica A; Lacy-Hulbert, Adam; Piliponsky, Adrian M; Ziegler, Steven F; Altemeier, William A; Debley, Jason S; Gharib, Sina A; Hallstrand, Teal S.

Am J Respir Cell Mol Biol ; 63(6): 859-863, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-32946274

18.

Dectin-1-dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages.

Tam, Jenny M; Mansour, Michael K; Khan, Nida S; Seward, Michael; Puranam, Sravanthi; Tanne, Antoine; Sokolovska, Anna; Becker, Christine E; Acharya, Mridu; Baird, Michelle A; Choi, Augustine M K; Davidson, Michael W; Segal, Brahm H; Lacy-Hulbert, Adam; Stuart, Lynda M; Xavier, Ramnik J; Vyas, Jatin M.

J Infect Dis ; 210(11): 1844-54, 2014 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-24842831

19.

Integrin αv in the mechanical response of osteoblast lineage cells.

Kaneko, Keiko; Ito, Masako; Naoe, Yoshinori; Lacy-Hulbert, Adam; Ikeda, Kyoji.

Biochem Biophys Res Commun ; 447(2): 352-7, 2014 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-24726648

20.

The astrocyte-expressed integrin αvß8 governs blood vessel sprouting in the developing retina.

Hirota, Shinya; Liu, Qian; Lee, Hye Shin; Hossain, Mohammad G; Lacy-Hulbert, Adam; McCarty, Joseph H.

Development ; 138(23): 5157-66, 2011 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-22069187

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