Detalhe da pesquisa
1.
Structural Features Affecting the Interactions and Transportability of LAT1-Targeted Phenylalanine Drug Conjugates.
Mol Pharm
; 20(1): 206-218, 2023 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36394563
2.
Synthesis, Structural and Behavioral Studies of Indole Derivatives D2AAK5, D2AAK6 and D2AAK7 as Serotonin 5-HT1A and 5-HT2A Receptor Ligands.
Molecules
; 28(1)2023 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36615578
3.
In Vitro Identification and In Vivo Confirmation of Inhibitors for Sweet Potato Chlorotic Stunt Virus RNA Silencing Suppressor, a Viral RNase III.
J Virol
; 95(12)2021 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33827953
4.
SARS-CoV-2-host proteome interactions for antiviral drug discovery.
Mol Syst Biol
; 17(11): e10396, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34709727
5.
Synthesis and evaluation of 1,2,3-dithiazole inhibitors of the nucleocapsid protein of feline immunodeficiency virus (FIV) as a model for HIV infection.
Bioorg Med Chem
; 68: 116834, 2022 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35653871
6.
Identification of Key Amino Acids that Impact Organic Solute Transporter α/ß (OSTα/ß).
Mol Pharmacol
; 100(6): 599-608, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34599072
7.
Structural Characterization of LsrK as a Quorum Sensing Target and a Comparison between X-ray and Homology Models.
J Chem Inf Model
; 61(3): 1346-1353, 2021 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33683884
8.
Molecular characteristics supporting l-Type amino acid transporter 1 (LAT1)-mediated translocation.
Bioorg Chem
; 112: 104921, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33933805
9.
Docking-Based 3D-QSAR Studies for 1,3,4-oxadiazol-2-one Derivatives as FAAH Inhibitors.
Int J Mol Sci
; 22(11)2021 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34204026
10.
Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors.
Molecules
; 26(19)2021 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34641454
11.
New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K).
Molecules
; 25(7)2020 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32272798
12.
Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System.
Antimicrob Agents Chemother
; 64(1)2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611347
13.
Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling.
PLoS Comput Biol
; 14(9): e1006458, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30199525
14.
Synthesis and comparison of substituted 1,2,3-dithiazole and 1,2,3-thiaselenazole as inhibitors of the feline immunodeficiency virus (FIV) nucleocapsid protein as a model for HIV infection.
Bioorg Med Chem Lett
; 29(14): 1765-1768, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31101470
15.
Novel epidithiodiketopiperazines as anti-viral zinc ejectors of the Feline Immunodeficiency Virus (FIV) nucleocapsid protein as a model for HIV infection.
Bioorg Med Chem
; 27(18): 4174-4184, 2019 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31395510
16.
In Vitro and in Silico Evaluation of Bikaverin as a Potent Inhibitor of Human Protein Kinase CK2.
Molecules
; 24(7)2019 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30965682
17.
Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK).
Molecules
; 24(22)2019 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31698822
18.
The Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs.
Nucleic Acids Res
; 44(4): 1760-75, 2016 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26826707
19.
1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors.
Molecules
; 23(5)2018 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29783765
20.
Structural review of PPARγ in complex with ligands: Cartesian- and dihedral angle principal component analyses of X-ray crystallographic data.
Proteins
; 85(9): 1684-1698, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28543443