Detalhe da pesquisa
1.
Regulation of Kappa Opioid Receptor Inactivation Depends on Sex and Cellular Site of Antagonist Action.
Mol Pharmacol
; 98(5): 548-558, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913138
2.
Reactive oxygen species (ROS) generation is stimulated by κ opioid receptor activation through phosphorylated c-Jun N-terminal kinase and inhibited by p38 mitogen-activated protein kinase (MAPK) activation.
J Biol Chem
; 294(45): 16884-16896, 2019 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31575661
3.
Estrogen Regulation of GRK2 Inactivates Kappa Opioid Receptor Signaling Mediating Analgesia, But Not Aversion.
J Neurosci
; 38(37): 8031-8043, 2018 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30076211
4.
Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions.
Proc Natl Acad Sci U S A
; 112(26): 8106-11, 2015 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26056286
5.
Prefrontal D1 dopamine signaling is required for temporal control.
Proc Natl Acad Sci U S A
; 109(50): 20726-31, 2012 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23185016
6.
P2X7 receptor-dependent increase in endocannabinoid 2-arachidonoyl glycerol production by neuronal cells in culture: Dynamics and mechanism.
Br J Pharmacol
; 2024 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38581262
7.
Pharmacological characterization of the endocannabinoid sensor GRABeCB2.0.
bioRxiv
; 2023 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945533
8.
Pharmacological Characterization of the Endocannabinoid Sensor GRABeCB2.0.
Cannabis Cannabinoid Res
; 2023 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38064488
9.
Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking.
Proc Natl Acad Sci U S A
; 106(45): 19168-73, 2009 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19864633
10.
Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward.
Addict Neurosci
; 12022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36176476
11.
Stress decreases serotonin tone in the nucleus accumbens in male mice to promote aversion and potentiate cocaine preference via decreased stimulation of 5-HT1B receptors.
Neuropsychopharmacology
; 47(4): 891-901, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34564712
12.
Release of endogenous dynorphin opioids in the prefrontal cortex disrupts cognition.
Neuropsychopharmacology
; 46(13): 2330-2339, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34545197
13.
Insidious Transmission of a Stress-Related Neuroadaptation.
Front Behav Neurosci
; 14: 564054, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33132859
14.
Orally consumed cannabinoids provide long-lasting relief of allodynia in a mouse model of chronic neuropathic pain.
Neuropsychopharmacology
; 45(7): 1105-1114, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31812152
15.
The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system.
J Neurosci
; 28(2): 407-14, 2008 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18184783
16.
Repeated Administration of Norbinaltorphimine Produces Cumulative Kappa Opioid Receptor Inactivation.
Front Pharmacol
; 10: 88, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30787880
17.
Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria.
J Neurosci
; 27(43): 11614-23, 2007 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-17959804
18.
κ-Opioid Receptor Activation in Dopamine Neurons Disrupts Behavioral Inhibition.
Neuropsychopharmacology
; 43(2): 362-372, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28649993
19.
Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase.
Nat Commun
; 8(1): 743, 2017 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28963507
20.
Prior activation of kappa opioid receptors by U50,488 mimics repeated forced swim stress to potentiate cocaine place preference conditioning.
Neuropsychopharmacology
; 31(4): 787-94, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16123754