Detalhe da pesquisa
1.
Optimizing metabolic stability of phosphodiesterase 5 inhibitors: Discovery of a potent N-(pyridin-3-ylmethyl)quinoline derivative targeting synaptic plasticity.
Bioorg Med Chem Lett
; 92: 129409, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37453616
2.
Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies.
Blood
; 129(1): 88-99, 2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27784673
3.
Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates.
Chembiochem
; 16(15): 2205-2215, 2015 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26350723
4.
Chloride channel blockade relaxes airway smooth muscle and potentiates relaxation by ß-agonists.
Am J Physiol Lung Cell Mol Physiol
; 307(3): L273-82, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24879056
5.
The selective vasopressin type 1a receptor agonist selepressin (FE 202158) blocks vascular leak in ovine severe sepsis*.
Crit Care Med
; 42(7): e525-e533, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24674922
6.
Exploring the Landscape of Aptamers: From Cross-Reactive to Selective to Specific, High-Affinity Receptors for Cocaine.
JACS Au
; 4(2): 760-770, 2024 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38425914
7.
A pharmacological toolkit for human microglia identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer's disease.
bioRxiv
; 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38370689
8.
A functional group-guided approach to aptamers for small molecules.
Science
; 380(6648): 942-948, 2023 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37262137
9.
Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.
Nat Chem Biol
; 6(8): 602-9, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20581821
10.
Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase.
Bioorg Med Chem Lett
; 22(1): 601-5, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22079754
11.
The Vocation of a Doctor.
Linacre Q
; 79(1): 14-18, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30082956
12.
Distinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotype.
J Comput Aided Mol Des
; 25(9): 873-83, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21904909
13.
Vasopressin deficiency and vasodilatory state in end-stage liver disease.
J Cardiothorac Vasc Anesth
; 25(4): 665-70, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21126886
14.
Locations of the beta1 transmembrane helices in the BK potassium channel.
Proc Natl Acad Sci U S A
; 105(31): 10727-32, 2008 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18669652
15.
Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity.
Proc Natl Acad Sci U S A
; 105(6): 2198-202, 2008 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18268335
16.
Post-acute COVID-19 syndrome.
Nat Med
; 27(4): 601-615, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33753937
17.
Location of the beta 4 transmembrane helices in the BK potassium channel.
J Neurosci
; 29(26): 8321-8, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19571123
18.
Phosphodiesterase 5 inhibition improves synaptic function, memory, and amyloid-beta load in an Alzheimer's disease mouse model.
J Neurosci
; 29(25): 8075-86, 2009 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19553447
19.
Increased complexity of vasopressin's vascular actions.
Crit Care
; 14(6): 1011, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-21156084
20.
Development of novel phosphodiesterase 5 inhibitors for the therapy of Alzheimer's disease.
Biochem Pharmacol
; 176: 113818, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31978378