Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Transcriptome dynamics of CD4⁺ T cells during malaria maps gradual transit from effector to memory.

Soon, Megan S F; Lee, Hyun Jae; Engel, Jessica A; Straube, Jasmin; Thomas, Bryce S; Pernold, Clara P S; Clarke, Lachlan S; Laohamonthonkul, Pawat; Haldar, Rohit N; Williams, Cameron G; Lansink, Lianne I M; Moreira, Marcela L; Bramhall, Michael; Koufariotis, Lambros T; Wood, Scott; Chen, Xi; James, Kylie R; Lönnberg, Tapio; Lane, Steven W; Belz, Gabrielle T; Engwerda, Christian R; Khoury, David S; Davenport, Miles P; Svensson, Valentine; Teichmann, Sarah A; Haque, Ashraful.

Nat Immunol ; 21(12): 1597-1610, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33046889

2.

AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.

Sykes, Stephen M; Lane, Steven W; Bullinger, Lars; Kalaitzidis, Demetrios; Yusuf, Rushdia; Saez, Borja; Ferraro, Francesca; Mercier, Francois; Singh, Harshabad; Brumme, Kristina M; Acharya, Sanket S; Scholl, Claudia; Schöll, Claudia; Tothova, Zuzana; Attar, Eyal C; Fröhling, Stefan; DePinho, Ronald A; Armstrong, Scott A; Gilliland, D Gary; Scadden, David T.

Cell ; 146(5): 697-708, 2011 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-21884932

3.

Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.

Jayavelu, Ashok Kumar; Schnöder, Tina M; Perner, Florian; Herzog, Carolin; Meiler, Arno; Krishnamoorthy, Gurumoorthy; Huber, Nicolas; Mohr, Juliane; Edelmann-Stephan, Bärbel; Austin, Rebecca; Brandt, Sabine; Palandri, Francesca; Schröder, Nicolas; Isermann, Berend; Edlich, Frank; Sinha, Amit U; Ungelenk, Martin; Hübner, Christian A; Zeiser, Robert; Rahmig, Susann; Waskow, Claudia; Coldham, Iain; Ernst, Thomas; Hochhaus, Andreas; Jilg, Stefanie; Jost, Philipp J; Mullally, Ann; Bullinger, Lars; Mertens, Peter R; Lane, Steven W; Mann, Matthias; Heidel, Florian H.

Nature ; 588(7836): 157-163, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33239784

4.

Genome-wide transcription factor-binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs.

Subramanian, Shruthi; Thoms, Julie A I; Huang, Yizhou; Cornejo-Páramo, Paola; Koch, Forrest C; Jacquelin, Sebastien; Shen, Sylvie; Song, Emma; Joshi, Swapna; Brownlee, Chris; Woll, Petter S; Chacon-Fajardo, Diego; Beck, Dominik; Curtis, David J; Yehson, Kenneth; Antonenas, Vicki; O'Brien, Tracey; Trickett, Annette; Powell, Jason A; Lewis, Ian D; Pitson, Stuart M; Gandhi, Maher K; Lane, Steven W; Vafaee, Fatemeh; Wong, Emily S; Göttgens, Berthold; Alinejad-Rokny, Hamid; Wong, Jason W H; Pimanda, John E.

Blood ; 142(17): 1448-1462, 2023 10 26.

Artigo em Inglês | MEDLINE | ID: mdl-37595278

5.

PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.

Schnoeder, Tina M; Schwarzer, Adrian; Jayavelu, Ashok Kumar; Hsu, Chen-Jen; Kirkpatrick, Joanna; Döhner, Konstanze; Perner, Florian; Eifert, Theresa; Huber, Nicolas; Arreba-Tutusaus, Patricia; Dolnik, Anna; Assi, Salam A; Nafria, Monica; Jiang, Lu; Dai, Yu-Ting; Chen, Zhu; Chen, Sai-Juan; Kellaway, Sophie G; Ptasinska, Anetta; Ng, Elizabeth S; Stanley, Edouard G; Elefanty, Andrew G; Buschbeck, Marcus; Bierhoff, Holger; Brodt, Steffen; Matziolis, Georg; Fischer, Klaus-Dieter; Hochhaus, Andreas; Chen, Chun-Wei; Heidenreich, Olaf; Mann, Matthias; Lane, Steven W; Bullinger, Lars; Ori, Alessandro; von Eyss, Björn; Bonifer, Constanze; Heidel, Florian H.

Blood ; 139(7): 1080-1097, 2022 02 17.

Artigo em Inglês | MEDLINE | ID: mdl-34695195

6.

Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.

Tubío-Santamaría, Nuria; Jayavelu, Ashok Kumar; Schnoeder, Tina M; Eifert, Theresa; Hsu, Chen-Jen; Perner, Florian; Zhang, Qirui; Wenge, Daniela V; Hansen, Fynn M; Kirkpatrick, Joanna M; Jyotsana, Nidhi; Lane, Steven W; von Eyss, Björn; Deshpande, Aniruddha J; Kühn, Michael W M; Schwaller, Juerg; Cammann, Clemens; Seifert, Ulrike; Ebstein, Frédéric; Krüger, Elke; Hochhaus, Andreas; Heuser, Michael; Ori, Alessandro; Mann, Matthias; Armstrong, Scott A; Heidel, Florian H.

Mol Cancer ; 22(1): 196, 2023 12 04.

Artigo em Inglês | MEDLINE | ID: mdl-38049829

7.

IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease.

Henden, Andrea S; Koyama, Motoko; Robb, Renee J; Forero, Adriana; Kuns, Rachel D; Chang, Karshing; Ensbey, Kathleen S; Varelias, Antiopi; Kazakoff, Stephen H; Waddell, Nicole; Clouston, Andrew D; Giri, Rabina; Begun, Jakob; Blazar, Bruce R; Degli-Esposti, Mariapia A; Kotenko, Sergei V; Lane, Steven W; Bowerman, Kate L; Savan, Ram; Hugenholtz, Philip; Gartlan, Kate H; Hill, Geoffrey R.

Blood ; 138(8): 722-737, 2021 08 26.

Artigo em Inglês | MEDLINE | ID: mdl-34436524

8.

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias.

Thijssen, Rachel; Diepstraten, Sarah T; Moujalled, Donia; Chew, Edward; Flensburg, Christoffer; Shi, Melissa X; Dengler, Michael A; Litalien, Veronique; MacRaild, Sarah; Chen, Maoshan; Anstee, Natasha S; Reljic, Boris; Gabriel, Sarah S; Djajawi, Tirta M; Riffkin, Chris D; Aubrey, Brandon J; Chang, Catherine; Tai, Lin; Xu, Zhen; Morley, Thomas; Pomilio, Giovanna; Bruedigam, Claudia; Kallies, Axel; Stroud, David A; Bajel, Ashish; Kluck, Ruth M; Lane, Steven W; Schoumacher, Marie; Banquet, Sébastien; Majewski, Ian J; Strasser, Andreas; Roberts, Andrew W; Huang, David C S; Brown, Fiona C; Kelly, Gemma L; Wei, Andrew H.

Blood ; 137(20): 2721-2735, 2021 05 20.

Artigo em Inglês | MEDLINE | ID: mdl-33824975

9.

Optimizing DNA hypomethylating therapy in acute myeloid leukemia and myelodysplastic syndromes.

Straube, Jasmin; Lane, Steven W; Vu, Therese.

Bioessays ; 43(10): e2100125, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34463368

10.

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.

Walter, Dagmar; Lier, Amelie; Geiselhart, Anja; Thalheimer, Frederic B; Huntscha, Sina; Sobotta, Mirko C; Moehrle, Bettina; Brocks, David; Bayindir, Irem; Kaschutnig, Paul; Muedder, Katja; Klein, Corinna; Jauch, Anna; Schroeder, Timm; Geiger, Hartmut; Dick, Tobias P; Holland-Letz, Tim; Schmezer, Peter; Lane, Steven W; Rieger, Michael A; Essers, Marieke A G; Williams, David A; Trumpp, Andreas; Milsom, Michael D.

Nature ; 520(7548): 549-52, 2015 Apr 23.

Artigo em Inglês | MEDLINE | ID: mdl-25707806

11.

BET inhibitor resistance emerges from leukaemia stem cells.

Fong, Chun Yew; Gilan, Omer; Lam, Enid Y N; Rubin, Alan F; Ftouni, Sarah; Tyler, Dean; Stanley, Kym; Sinha, Devbarna; Yeh, Paul; Morison, Jessica; Giotopoulos, George; Lugo, Dave; Jeffrey, Philip; Lee, Stanley Chun-Wei; Carpenter, Christopher; Gregory, Richard; Ramsay, Robert G; Lane, Steven W; Abdel-Wahab, Omar; Kouzarides, Tony; Johnstone, Ricky W; Dawson, Sarah-Jane; Huntly, Brian J P; Prinjha, Rab K; Papenfuss, Anthony T; Dawson, Mark A.

Nature ; 525(7570): 538-42, 2015 Sep 24.

Artigo em Inglês | MEDLINE | ID: mdl-26367796

12.

Shelter from the cytokine storm in myelofibrosis.

Lane, Steven W.

Blood ; 141(20): 2415-2416, 2023 05 18.

Artigo em Inglês | MEDLINE | ID: mdl-37200061

13.

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.

Jacquelin, Sebastien; Straube, Jasmin; Cooper, Leanne; Vu, Therese; Song, Axia; Bywater, Megan; Baxter, Eva; Heidecker, Matthew; Wackrow, Brad; Porter, Amy; Ling, Victoria; Green, Joanne; Austin, Rebecca; Kazakoff, Stephen; Waddell, Nicola; Hesson, Luke B; Pimanda, John E; Stegelmann, Frank; Bullinger, Lars; Döhner, Konstanze; Rampal, Raajit K; Heckl, Dirk; Hill, Geoffrey R; Lane, Steven W.

Blood ; 132(26): 2707-2721, 2018 12 27.

Artigo em Inglês | MEDLINE | ID: mdl-30366920

14.

IFN Regulatory Factor 3 Balances Th1 and T Follicular Helper Immunity during Nonlethal Blood-Stage Plasmodium Infection.

James, Kylie R; Soon, Megan S F; Sebina, Ismail; Fernandez-Ruiz, Daniel; Davey, Gayle; Liligeto, Urijah N; Nair, Arya Sheela; Fogg, Lily G; Edwards, Chelsea L; Best, Shannon E; Lansink, Lianne I M; Schroder, Kate; Wilson, Jane A C; Austin, Rebecca; Suhrbier, Andreas; Lane, Steven W; Hill, Geoffrey R; Engwerda, Christian R; Heath, William R; Haque, Ashraful.

J Immunol ; 200(4): 1443-1456, 2018 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-29321276

15.

Managing haematology and oncology patients during the COVID-19 pandemic: interim consensus guidance.

Weinkove, Robert; McQuilten, Zoe K; Adler, Jonathan; Agar, Meera R; Blyth, Emily; Cheng, Allen C; Conyers, Rachel; Haeusler, Gabrielle M; Hardie, Claire; Jackson, Christopher; Lane, Steven W; Middlemiss, Tom; Mollee, Peter; Mulligan, Stephen P; Ritchie, David; Ruka, Myra; Solomon, Benjamin; Szer, Jeffrey; Thursky, Karin A; Wood, Erica M; Worth, Leon J; Yong, Michelle K; Slavin, Monica A; Teh, Benjamin W.

Med J Aust ; 212(10): 481-489, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32401360

16.

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity.

Bunting, Mark D; Varelias, Antiopi; Souza-Fonseca-Guimaraes, Fernando; Schuster, Iona S; Lineburg, Katie E; Kuns, Rachel D; Fleming, Peter; Locke, Kelly R; Huntington, Nicholas D; Blazar, Bruce R; Lane, Steven W; Tey, Siok-Keen; MacDonald, Kelli P A; Smyth, Mark J; Degli-Esposti, Mariapia A; Hill, Geoffrey R.

Blood ; 129(5): 630-642, 2017 02 02.

Artigo em Inglês | MEDLINE | ID: mdl-27927647

17.

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.

Shi, Wei; Vu, Therese; Boucher, Didier; Biernacka, Anna; Nde, Jules; Pandita, Raj K; Straube, Jasmin; Boyle, Glen M; Al-Ejeh, Fares; Nag, Purba; Jeffery, Jessie; Harris, Janelle L; Bain, Amanda L; Grzelak, Marta; Skrzypczak, Magdalena; Mitra, Abhishek; Dojer, Norbert; Crosetto, Nicola; Cloonan, Nicole; Becherel, Olivier J; Finnie, John; Skaar, Jeffrey R; Walkley, Carl R; Pandita, Tej K; Rowicka, Maga; Ginalski, Krzysztof; Lane, Steven W; Khanna, Kum Kum.

Blood ; 129(18): 2479-2492, 2017 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-28270450

18.

Recommendations for the use of pegylated interferon-α in the treatment of classical myeloproliferative neoplasms.

Forsyth, Cecily J; Chan, Wai-Hoong; Grigg, Andrew P; Cook, Nathalie C; Lane, Steven W; Burbury, Kate L; Perkins, Andrew C; Ross, David M.

Intern Med J ; 49(8): 948-954, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-30411442

19.

The TRIM31 paradox: an unexpected benefit for leukemia stem cells.

Straube, Jasmin; Lane, Steven W.

Haematologica ; 108(8): 1982-1983, 2023 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-36924255

20.

t(15;17) in acute promyelocytc leukemia.

Ling, Victoria Y; Lane, Steven W.

Haematologica ; 108(2): 295-296, 2023 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-36722400

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