Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024.

Masirika, Leandre Murhula; Udahemuka, Jean Claude; Schuele, Leonard; Ndishimye, Pacifique; Otani, Saria; Mbiribindi, Justin Bengehya; Marekani, Jean M; Mambo, Léandre Mutimbwa; Bubala, Nadine Malyamungu; Boter, Marjan; Nieuwenhuijse, David F; Lang, Trudie; Kalalizi, Ernest Balyahamwabo; Musabyimana, Jean Pierre; Aarestrup, Frank M; Koopmans, Marion; Oude Munnink, Bas B; Siangoli, Freddy Belesi.

Euro Surveill ; 29(11)2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38487886

2.

Strengthening research ethics governance and regulatory oversight in Central America and the Dominican Republic in response to the COVID-19 pandemic: a qualitative study.

Canario Guzmán, Julio Arturo; Orlich, Jessie; Mendizábal-Cabrera, Renata; Ying, Argentina; Vergès, Claude; Espinoza, Eleonora; Soriano, Mario; Cárcamo, Elsy; Beltrán, Briana; Mendoza Marrero, Eddys Rafael; Sepulveda, Reyna; Nieto Anderson, Claudia; Feune de Colombi, Nicole; Lescano, Roxana; Pérez-Then, Eddy; Lang, Trudie; Alger, Jackeline.

Health Res Policy Syst ; 20(1): 138, 2022 Dec 23.

Artigo em Inglês | MEDLINE | ID: mdl-36564837

3.

Plug COVID-19 research gaps in detection, prevention and care.

Lang, Trudie.

Nature ; 583(7816): 333, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-32669692

4.

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial.

Dunning, Jake; Sahr, Foday; Rojek, Amanda; Gannon, Fiona; Carson, Gail; Idriss, Baimba; Massaquoi, Thomas; Gandi, Regina; Joseph, Sebatu; Osman, Hassan K; Brooks, Timothy J G; Simpson, Andrew J H; Goodfellow, Ian; Thorne, Lucy; Arias, Armando; Merson, Laura; Castle, Lyndsey; Howell-Jones, Rebecca; Pardinaz-Solis, Raul; Hope-Gill, Benjamin; Ferri, Mauricio; Grove, Jennifer; Kowalski, Mark; Stepniewska, Kasia; Lang, Trudie; Whitehead, John; Olliaro, Piero; Samai, Mohammed; Horby, Peter W.

PLoS Med ; 13(4): e1001997, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-27093560

5.

Ebola: Embed research in outbreak response.

Lang, Trudie.

Nature ; 524(7563): 29-31, 2015 Aug 06.

Artigo em Inglês | MEDLINE | ID: mdl-26245565

6.

Trial design for evaluating novel treatments during an outbreak of an infectious disease.

Whitehead, John; Olliaro, Piero; Lang, Trudie; Horby, Peter.

Clin Trials ; 13(1): 31-8, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26768556

7.

Evaluating clinical trial designs for investigational treatments of Ebola virus disease.

Cooper, Ben S; Boni, Maciej F; Pan-ngum, Wirichada; Day, Nicholas P J; Horby, Peter W; Olliaro, Piero; Lang, Trudie; White, Nicholas J; White, Lisa J; Whitehead, John.

PLoS Med ; 12(4): e1001815, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25874579

8.

Mortality after fluid bolus in African children with severe infection.

Maitland, Kathryn; Kiguli, Sarah; Opoka, Robert O; Engoru, Charles; Olupot-Olupot, Peter; Akech, Samuel O; Nyeko, Richard; Mtove, George; Reyburn, Hugh; Lang, Trudie; Brent, Bernadette; Evans, Jennifer A; Tibenderana, James K; Crawley, Jane; Russell, Elizabeth C; Levin, Michael; Babiker, Abdel G; Gibb, Diana M.

N Engl J Med ; 364(26): 2483-95, 2011 Jun 30.

Artigo em Inglês | MEDLINE | ID: mdl-21615299

9.

Investigating the Secondary Use of Clinical Research Data: Protocol for a Mixed Methods Study.

Waithira, Naomi; Kestelyn, Evelyne; Chotthanawathit, Keitcheya; Osterrieder, Anne; Mukaka, Mavuto; Lang, Trudie; Cheah, Phaik Yeong.

JMIR Res Protoc ; 12: e44875, 2023 Mar 06.

Artigo em Inglês | MEDLINE | ID: mdl-36877564

10.

Enabling evidence to tackle everyday diseases to mitigate another pandemic.

Lang, Trudie.

Gates Open Res ; 6: 45, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35923865

11.

Creating equity in health research to drive more and better evidence.

Lang, Trudie; Reeder, John; Moorthy, Vasee; Trindade Lima, Nísia; Gray, Glenda; Kaleebu, Pontiano; Ihekweazu, Chikwe; Nsanzimana, Sabin; Kang, Gagandeep; Makanga, Michael; Swaminathan, Soumya.

Wellcome Open Res ; 7: 15, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-38031536

12.

The European & Developing Countries Clinical Trials Partnership (EDCTP) Knowledge Hub: developing an open platform for facilitating high-quality clinical research.

Driver, Samuel; Gray, Shan; Sikhondze, Welile; Awuonda, Ken; Wilcox, Helena; Segrt, Alexis; Pandya, Lara; Roth, Johanna; Makanga, Michael; Lang, Trudie.

Trials ; 23(1): 374, 2022 May 07.

Artigo em Inglês | MEDLINE | ID: mdl-35526046

13.

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age.

Bejon, Philip; Lusingu, John; Olotu, Ally; Leach, Amanda; Lievens, Marc; Vekemans, Johan; Mshamu, Salum; Lang, Trudie; Gould, Jayne; Dubois, Marie-Claude; Demoitié, Marie-Ange; Stallaert, Jean-Francois; Vansadia, Preeti; Carter, Terrell; Njuguna, Patricia; Awuondo, Ken O; Malabeja, Anangisye; Abdul, Omar; Gesase, Samwel; Mturi, Neema; Drakeley, Chris J; Savarese, Barbara; Villafana, Tonya; Ballou, W Ripley; Cohen, Joe; Riley, Eleanor M; Lemnge, Martha M; Marsh, Kevin; von Seidlein, Lorenz.

N Engl J Med ; 359(24): 2521-32, 2008 Dec 11.

Artigo em Inglês | MEDLINE | ID: mdl-19064627

14.

A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers.

Chilengi, Roma; Juma, Rashid; Abdallah, Ahmed M; Bashraheil, Mahfudh; Lodenyo, Hudson; Nyakundi, Priscilla; Anabwani, Evelyn; Salim, Amina; Mwambingu, Gabriel; Wenwa, Ednah; Jemutai, Julie; Kipkeu, Chemtai; Oyoo, George O; Muchohi, Simon N; Kokwaro, Gilbert; Niehues, Tim; Lang, Trudie; Nzila, Alexis.

Malar J ; 10: 63, 2011 Mar 16.

Artigo em Inglês | MEDLINE | ID: mdl-21410944

15.

Measuring research capacity development in healthcare workers: a systematic review.

Bilardi, Davide; Rapa, Elizabeth; Bernays, Sarah; Lang, Trudie.

BMJ Open ; 11(7): e046796, 2021 07 07.

Artigo em Inglês | MEDLINE | ID: mdl-34233984

16.

Setting up a pragmatic clinical trial in a low-resource setting: A qualitative assessment of GoLBeT, a trial of podoconiosis management in Northern Ethiopia.

Erber, Astrid C; Ewing, Victoria; Turner, Mark; Molla, Meseret; Murbe, Gharib; Enquoselassie, Fikre; Davey, Gail; Lang, Trudie.

PLoS Negl Trop Dis ; 15(7): e0009582, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34319977

17.

Engaging local health research communities to enhance long-term capacity building in Brazil.

Madia Lourenço, Luiza Helena; Baker, Bonny Louise; Dias Junior, Antonio Gregorio; Jamieson, Nina E; Pacheco de Almeida, Roque; Queiroz Gurgel, Ricardo; Campello Bresani Salvi, Cristiane; de Souza, Clécio Gabriel; Longo, Egmar; Gomes, Bruno; Rocha David, Mariana; Galvão Pavan, Márcio; Pereira de Castro, Daniele; Lacerda Nogueira, Mauricio; Lang, Trudie.

BMJ Glob Health ; 6(10)2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34670775

18.

The legacy of ZikaPLAN: a transnational research consortium addressing Zika.

Wilder-Smith, Annelies; Brickley, Elizabeth B; Ximenes, Ricardo Arraes de Alencar; Miranda-Filho, Demócrito de Barros; Turchi Martelli, Celina Maria; Solomon, Tom; Jacobs, Bart C; Pardo, Carlos A; Osorio, Lyda; Parra, Beatriz; Lant, Suzannah; Willison, Hugh J; Leonhard, Sonja; Turtle, Lance; Ferreira, Maria Lúcia Brito; de Oliveira Franca, Rafael Freitas; Lambrechts, Louis; Neyts, Johan; Kaptein, Suzanne; Peeling, Rosanna; Boeras, Deborah; Logan, James; Dolk, Helen; Orioli, Ieda M; Neumayr, Andreas; Lang, Trudie; Baker, Bonny; Massad, Eduardo; Preet, Raman.

Glob Health Action ; 14(sup1): 2008139, 2021 10 26.

Artigo em Inglês | MEDLINE | ID: mdl-35377284

19.

Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts.

Masraf, Hannah; Azemeraw, Temesgen; Molla, Meseret; Jones, Christopher Iain; Bremner, Stephen; Ngari, Moses; Berkley, James A; Kivaya, Esther; Fegan, Greg; Tamiru, Abreham; Kelemework, Abebe; Lang, Trudie; Newport, Melanie J; Davey, Gail.

Trans R Soc Trop Med Hyg ; 114(12): 1035-1037, 2020 12 16.

Artigo em Inglês | MEDLINE | ID: mdl-33236119

20.

Patients' preferences of cutaneous leishmaniasis treatment outcomes: Findings from an international qualitative study.

Erber, Astrid C; Arana, Byron; Ben Salah, Afif; Bennis, Issam; Boukthir, Aicha; Castro Noriega, María Del Mar; Cissé, Mamoudou; Cota, Gláucia Fernandes; Handjani, Farhad; López-Carvajal, Liliana; Marsh, Kevin; Medina, Dalila Martínez; Plugge, Emma; Lang, Trudie; Olliaro, Piero.

PLoS Negl Trop Dis ; 14(2): e0007996, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-32092059

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Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024.

Strengthening research ethics governance and regulatory oversight in Central America and the Dominican Republic in response to the COVID-19 pandemic: a qualitative study.

Plug COVID-19 research gaps in detection, prevention and care.

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial.

Ebola: Embed research in outbreak response.

Trial design for evaluating novel treatments during an outbreak of an infectious disease.

Evaluating clinical trial designs for investigational treatments of Ebola virus disease.

Mortality after fluid bolus in African children with severe infection.

Investigating the Secondary Use of Clinical Research Data: Protocol for a Mixed Methods Study.

Enabling evidence to tackle everyday diseases to mitigate another pandemic.

Creating equity in health research to drive more and better evidence.

The European & Developing Countries Clinical Trials Partnership (EDCTP) Knowledge Hub: developing an open platform for facilitating high-quality clinical research.

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age.

A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers.

Measuring research capacity development in healthcare workers: a systematic review.

Setting up a pragmatic clinical trial in a low-resource setting: A qualitative assessment of GoLBeT, a trial of podoconiosis management in Northern Ethiopia.

Engaging local health research communities to enhance long-term capacity building in Brazil.

The legacy of ZikaPLAN: a transnational research consortium addressing Zika.

Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts.

Patients' preferences of cutaneous leishmaniasis treatment outcomes: Findings from an international qualitative study.