Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Effect of Porosity on the Colonization of Digital Light-Processed 3D Hydrogel Constructs toward the Development of a Functional Intestinal Model.

Szabó, Anna; De Vlieghere, Elly; Costa, Pedro F; Geurs, Indi; Dewettinck, Koen; Maes, Laure; Laukens, Debby; Van Vlierberghe, Sandra.

Biomacromolecules ; 25(5): 2863-2874, 2024 May 13.

Artigo em Inglês | MEDLINE | ID: mdl-38564884

2.

Effect of 5-Hydroxytryptophan on Fatigue in Quiescent Inflammatory Bowel Disease: A Randomized Controlled Trial.

Truyens, Marie; Lobatón, Triana; Ferrante, Marc; Bossuyt, Peter; Vermeire, Séverine; Pouillon, Lieven; Dewint, Pieter; Cremer, Anneline; Peeters, Harald; Lambrecht, Guy; Louis, Edouard; Rahier, Jean-François; Dewit, Olivier; Muls, Vinciane; Holvoet, Tom; Vandermeulen, Liv; Peeters, Anneleen; Gonzales, Gerard Bryan; Bos, Simon; Laukens, Debby; De Vos, Martine.

Gastroenterology ; 163(5): 1294-1305.e3, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-35940251

3.

MRI texture analysis of T2-weighted images is preferred over magnetization transfer imaging for readily longitudinal quantification of gut fibrosis.

De Kock, Isabelle; Bos, Simon; Delrue, Louke; Van Welden, Sophie; Bunyard, Peter; Hindryckx, Pieter; De Vos, Martine; Villeirs, Geert; Laukens, Debby.

Eur Radiol ; 33(9): 5943-5952, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37071162

4.

The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice: a new factor in the host-microbiome interaction.

Wynendaele, Evelien; Debunne, Nathan; Janssens, Yorick; De Spiegeleer, Anton; Verbeke, Frederick; Tack, Liesa; Van Welden, Sophie; Goossens, Evy; Knappe, Daniel; Hoffmann, Ralf; Van De Wiele, Christophe; Laukens, Debby; Van Eenoo, Peter; Vereecke, Lars; Van Immerseel, Filip; De Wever, Olivier; De Spiegeleer, Bart.

BMC Biol ; 20(1): 151, 2022 06 27.

Artigo em Inglês | MEDLINE | ID: mdl-35761265

5.

Versatile human in vitro triple coculture model coincubated with adhered gut microbes reproducibly mimics pro-inflammatory host-microbe interactions in the colon.

Beterams, Annelore; De Paepe, Kim; Maes, Laure; Wise, India Jane; De Keersmaecker, Herlinde; Rajkovic, Andreja; Laukens, Debby; Van de Wiele, Tom; Calatayud Arroyo, Marta.

FASEB J ; 35(12): e21992, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34719821

6.

Reply.

Laukens, Debby; Truyens, Marie.

Gastroenterology ; 164(6): 1028-1029, 2023 May.

Artigo em Inglês | MEDLINE | ID: mdl-36738976

7.

Treatment of Intestinal Fibrosis in Experimental Inflammatory Bowel Disease by the Pleiotropic Actions of a Local Rho Kinase Inhibitor.

Holvoet, Tom; Devriese, Sarah; Castermans, Karolien; Boland, Sandro; Leysen, Dirk; Vandewynckel, Yves-Paul; Devisscher, Lindsey; Van den Bossche, Lien; Van Welden, Sophie; Dullaers, Melissa; Vandenbroucke, Roosmarijn E; De Rycke, Riet; Geboes, Karel; Bourin, Arnaud; Defert, Olivier; Hindryckx, Pieter; De Vos, Martine; Laukens, Debby.

Gastroenterology ; 153(4): 1054-1067, 2017 10.

Artigo em Inglês | MEDLINE | ID: mdl-28642198

8.

Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.

Van Welden, Sophie; De Vos, Martine; Wielockx, Ben; Tavernier, Simon J; Dullaers, Melissa; Neyt, Sara; Descamps, Benedicte; Devisscher, Lindsey; Devriese, Sarah; Van den Bossche, Lien; Holvoet, Tom; Baeyens, Ann; Correale, Carmen; D'Alessio, Silvia; Vanhove, Christian; De Vos, Filip; Verhasselt, Bruno; Breier, Georg; Lambrecht, Bart N; Janssens, Sophie; Carmeliet, Peter; Danese, Silvio; Elewaut, Dirk; Laukens, Debby; Hindryckx, Pieter.

J Pathol ; 241(4): 547-558, 2017 03.

Artigo em Inglês | MEDLINE | ID: mdl-27981571

9.

Tauroursodeoxycholic acid protects bile acid homeostasis under inflammatory conditions and dampens Crohn's disease-like ileitis.

Van den Bossche, Lien; Borsboom, Daniel; Devriese, Sarah; Van Welden, Sophie; Holvoet, Tom; Devisscher, Lindsey; Hindryckx, Pieter; De Vos, Martine; Laukens, Debby.

Lab Invest ; 97(5): 519-529, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28165466

10.

T84 monolayers are superior to Caco-2 as a model system of colonocytes.

Devriese, Sarah; Van den Bossche, Lien; Van Welden, Sophie; Holvoet, Tom; Pinheiro, Iris; Hindryckx, Pieter; De Vos, Martine; Laukens, Debby.

Histochem Cell Biol ; 148(1): 85-93, 2017 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-28265783

11.

Ursodeoxycholic Acid and Its Taurine- or Glycine-Conjugated Species Reduce Colitogenic Dysbiosis and Equally Suppress Experimental Colitis in Mice.

Van den Bossche, Lien; Hindryckx, Pieter; Devisscher, Lindsey; Devriese, Sarah; Van Welden, Sophie; Holvoet, Tom; Vilchez-Vargas, Ramiro; Vital, Marius; Pieper, Dietmar H; Vanden Bussche, Julie; Vanhaecke, Lynn; Van de Wiele, Tom; De Vos, Martine; Laukens, Debby.

Appl Environ Microbiol ; 83(7)2017 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-28115375

12.

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1.

Steeland, Sophie; Puimège, Leen; Vandenbroucke, Roosmarijn E; Van Hauwermeiren, Filip; Haustraete, Jurgen; Devoogdt, Nick; Hulpiau, Paco; Leroux-Roels, Geert; Laukens, Debby; Meuleman, Philip; De Vos, Martine; Libert, Claude.

J Biol Chem ; 290(7): 4022-37, 2015 Feb 13.

Artigo em Inglês | MEDLINE | ID: mdl-25538244

13.

Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut.

Allais, Liesbeth; Kerckhof, Frederiek-Maarten; Verschuere, Stephanie; Bracke, Ken R; De Smet, Rebecca; Laukens, Debby; Van den Abbeele, Pieter; De Vos, Martine; Boon, Nico; Brusselle, Guy G; Cuvelier, Claude A; Van de Wiele, Tom.

Environ Microbiol ; 18(5): 1352-63, 2016 05.

Artigo em Inglês | MEDLINE | ID: mdl-26033517

14.

Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma.

Vandewynckel, Yves-Paul; Laukens, Debby; Devisscher, Lindsey; Bogaerts, Eliene; Paridaens, Annelies; Van den Bussche, Anja; Raevens, Sarah; Verhelst, Xavier; Van Steenkiste, Christophe; Jonckx, Bart; Libbrecht, Louis; Geerts, Anja; Carmeliet, Peter; Van Vlierberghe, Hans.

BMC Cancer ; 16: 9, 2016 Jan 11.

Artigo em Inglês | MEDLINE | ID: mdl-26753564

15.

Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction.

Tulkens, Joeri; Vergauwen, Glenn; Van Deun, Jan; Geeurickx, Edward; Dhondt, Bert; Lippens, Lien; De Scheerder, Marie-Angélique; Miinalainen, Ilkka; Rappu, Pekka; De Geest, Bruno G; Vandecasteele, Katrien; Laukens, Debby; Vandekerckhove, Linos; Denys, Hannelore; Vandesompele, Jo; De Wever, Olivier; Hendrix, An.

Gut ; 69(1): 191-193, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-30518529

16.

Validated High Resolution Mass Spectrometry-Based Approach for Metabolomic Fingerprinting of the Human Gut Phenotype.

Vanden Bussche, Julie; Marzorati, Massimo; Laukens, Debby; Vanhaecke, Lynn.

Anal Chem ; 87(21): 10927-34, 2015 Nov 03.

Artigo em Inglês | MEDLINE | ID: mdl-26451617

17.

Role of metallothioneins as danger signals in the pathogenesis of colitis.

Devisscher, Lindsey; Hindryckx, Pieter; Lynes, Michael A; Waeytens, Anouk; Cuvelier, Claude; De Vos, Filip; Vanhove, Christian; Vos, Martine De; Laukens, Debby.

J Pathol ; 233(1): 89-100, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24452846

18.

Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death.

Laukens, Debby; Devisscher, Lindsey; Van den Bossche, Lien; Hindryckx, Pieter; Vandenbroucke, Roosmarijn E; Vandewynckel, Yves-Paul; Cuvelier, Claude; Brinkman, Brigitta M; Libert, Claude; Vandenabeele, Peter; De Vos, Martine.

Lab Invest ; 94(12): 1419-30, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25310532

19.

Hepatitis mouse models: from acute-to-chronic autoimmune hepatitis.

Yüksel, Muhammed; Laukens, Debby; Heindryckx, Femke; Van Vlierberghe, Hans; Geerts, Anja; Wong, F Susan; Wen, Li; Colle, Isabelle.

Int J Exp Pathol ; 95(5): 309-20, 2014 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25112417

20.

Endoplasmic reticulum stress and angiogenesis: is there an interaction between them?

Paridaens, Annelies; Laukens, Debby; Vandewynckel, Yves-Paul; Coulon, Stephanie; Van Vlierberghe, Hans; Geerts, Anja; Colle, Isabelle.

Liver Int ; 34(6): e10-8, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24393274

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