Detalhe da pesquisa
1.
Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways.
Hum Mol Genet
; 31(21): 3694-3714, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35567546
2.
DEAD-box RNA helicase Dbp4/DDX10 is an enhancer of α-synuclein toxicity and oligomerization.
PLoS Genet
; 17(3): e1009407, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33657088
3.
Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy.
EMBO J
; 37(1): 139-159, 2018 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29146773
4.
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo.
Neurobiol Dis
; 151: 105256, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33429042
5.
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
Proc Natl Acad Sci U S A
; 115(41): 10481-10486, 2018 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249646
6.
Synucleinopathies: Where we are and where we need to go.
J Neurochem
; 153(4): 433-454, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31957016
7.
The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.
PLoS Biol
; 15(3): e2000374, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28257421
8.
Correction: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.
PLoS Biol
; 15(4): e1002601, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379951
9.
The Interplay Between Proteostasis Systems and Parkinson's Disease.
Adv Exp Med Biol
; 1233: 223-236, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32274759
10.
Treatment with diphenyl-pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death.
Proc Natl Acad Sci U S A
; 114(25): E4971-E4977, 2017 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28584093
11.
C-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.
PLoS Genet
; 12(6): e1006098, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27341336
12.
Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function.
Neurobiol Dis
; 119: 121-135, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30092270
13.
Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells.
Cell Mol Neurobiol
; 38(8): 1539-1550, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30288631
14.
Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation.
PLoS Genet
; 10(11): e1004741, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25393002
15.
Small Molecules Detected by Second-Harmonic Generation Modulate the Conformation of Monomeric α-Synuclein and Reduce Its Aggregation in Cells.
J Biol Chem
; 290(46): 27582-93, 2015 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26396193
16.
Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells.
Mol Cell Neurosci
; 62: 51-9, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25109238
17.
α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner.
Neurobiol Dis
; 70: 149-61, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24983211
18.
Navigating through the complexities of synucleinopathies: Insights into pathogenesis, heterogeneity, and future perspectives.
Neuron
; 2024 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38861985
19.
In silico analysis of the aggregation propensity of the SARS-CoV-2 proteome: Insight into possible cellular pathologies.
Biochim Biophys Acta Proteins Proteom
; 1869(10): 140693, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34237472
20.
Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation.
Front Mol Neurosci
; 14: 659926, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33912013