Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing.

Pan, Yang; Phillips, John W; Zhang, Beatrice D; Noguchi, Miyako; Kutschera, Eric; McLaughlin, Jami; Nesterenko, Pavlo A; Mao, Zhiyuan; Bangayan, Nathanael J; Wang, Robert; Tran, Wendy; Yang, Harry T; Wang, Yuanyuan; Xu, Yang; Obusan, Matthew B; Cheng, Donghui; Lee, Alex H; Kadash-Edmondson, Kathryn E; Champhekar, Ameya; Puig-Saus, Cristina; Ribas, Antoni; Prins, Robert M; Seet, Christopher S; Crooks, Gay M; Witte, Owen N; Xing, Yi.

Proc Natl Acad Sci U S A ; 120(21): e2221116120, 2023 05 23.

Artigo em Inglês | MEDLINE | ID: mdl-37192158

2.

Structure and replication of yDNA: a novel genetic set widened by benzo-homologation.

Lu, Haige; Lynch, Stephen R; Lee, Alex H F; Kool, Eric T.

Chembiochem ; 10(15): 2530-8, 2009 Oct 12.

Artigo em Inglês | MEDLINE | ID: mdl-19780073

3.

Polymerase amplification, cloning, and gene expression of benzo-homologous "yDNA" base pairs.

Chelliserrykattil, Jijumon; Lu, Haige; Lee, Alex H F; Kool, Eric T.

Chembiochem ; 9(18): 2976-80, 2008 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-19053129

4.

Preparation of iron oxide silica particles for Zika viral RNA extraction.

Lee, Alex H F; Gessert, Steven F; Chen, Yutao; Sergeev, Nikolay V; Haghiri, Babak.

Heliyon ; 4(3): e00572, 2018 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-29556569

5.

Pilot study on the bioactivity of vitamin d in the skin after oral supplementation.

Curiel-Lewandrowski, Clara; Tang, Jean Y; Einspahr, Janine G; Bermudez, Yira; Hsu, Chiu Hsieh; Rezaee, Melika; Lee, Alex H; Tangrea, Joseph; Parnes, Howard L; Alberts, David S; Chow, H-H Sherry.

Cancer Prev Res (Phila) ; 8(6): 563-9, 2015 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-25835512

6.

Acid-accelerated DNA-cleaving activities of antitumor antibiotic varacin.

Lee, Alex H F; Chan, Albert S C; Li, Tianhu.

Chem Commun (Camb) ; (18): 2112-3, 2002 Sep 21.

Artigo em Inglês | MEDLINE | ID: mdl-12357803

7.

G-quadruplex as a new class of structural entities for directing the formation of circular oligodeoxyribonucleotides.

Chen, Jian; Liu, Dongsheng; Lee, Alex H F; Qi, Jianying; Chan, Albert S C; Li, Tianhu.

Chem Commun (Camb) ; (22): 2686-7, 2002 Nov 21.

Artigo em Inglês | MEDLINE | ID: mdl-12510299

8.

Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists.

Kim, James; Aftab, Blake T; Tang, Jean Y; Kim, Daniel; Lee, Alex H; Rezaee, Melika; Kim, Jynho; Chen, Baozhi; King, Emily M; Borodovsky, Alexandra; Riggins, Gregory J; Epstein, Ervin H; Beachy, Philip A; Rudin, Charles M.

Cancer Cell ; 23(1): 23-34, 2013 Jan 14.

Artigo em Inglês | MEDLINE | ID: mdl-23291299

9.

Small circular oligodeoxynucleotides achieved from self-assembling entities.

Liu, Dongsheng; Chen, Jian; Lee, Alex H F; Chow, Larry M C; Chan, Albert S C; Li, Tianhu.

Angew Chem Int Ed Engl ; 42(7): 797-9, 2003 Feb 17.

Artigo em Inglês | MEDLINE | ID: mdl-12596203

10.

Synthesis and properties of size-expanded DNAs: toward designed, functional genetic systems.

Krueger, Andrew T; Lu, Haige; Lee, Alex H F; Kool, Eric T.

Acc Chem Res ; 40(2): 141-50, 2007 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-17309194

11.

Exploring the limits of DNA size: naphtho-homologated DNA bases and pairs.

Lee, Alex H F; Kool, Eric T.

J Am Chem Soc ; 128(28): 9219-30, 2006 Jul 19.

Artigo em Inglês | MEDLINE | ID: mdl-16834396

12.

A new four-base genetic helix, yDNA, composed of widened benzopyrimidine-purine pairs.

Lee, Alex H F; Kool, Eric T.

J Am Chem Soc ; 127(10): 3332-8, 2005 Mar 16.

Artigo em Inglês | MEDLINE | ID: mdl-15755149

13.

Novel benzopyrimidines as widened analogues of DNA bases.

Lee, Alex H F; Kool, Eric T.

J Org Chem ; 70(1): 132-40, 2005 Jan 07.

Artigo em Inglês | MEDLINE | ID: mdl-15624915

14.

Benzotrithiole 2-oxide: a new family of thiol-activated DNA-cleaving functionalities.

Lee, Alex H F; Chan, Albert S C; Li, Tianhu.

Bioorg Med Chem Lett ; 12(22): 3259-61, 2002 Nov 18.

Artigo em Inglês | MEDLINE | ID: mdl-12392727

15.

Acid-promoted DNA-cleaving activities and total synthesis of varacin C.

Lee, Alex H F; Chen, Jian; Liu, Dongsheng; Leung, Thomas Y C; Chan, Albert S C; Li, Tianhu.

J Am Chem Soc ; 124(47): 13972-3, 2002 Nov 27.

Artigo em Inglês | MEDLINE | ID: mdl-12440877

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IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing.

Structure and replication of yDNA: a novel genetic set widened by benzo-homologation.

Polymerase amplification, cloning, and gene expression of benzo-homologous "yDNA" base pairs.

Preparation of iron oxide silica particles for Zika viral RNA extraction.

Pilot study on the bioactivity of vitamin d in the skin after oral supplementation.

Acid-accelerated DNA-cleaving activities of antitumor antibiotic varacin.

G-quadruplex as a new class of structural entities for directing the formation of circular oligodeoxyribonucleotides.

Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists.

Small circular oligodeoxynucleotides achieved from self-assembling entities.

Synthesis and properties of size-expanded DNAs: toward designed, functional genetic systems.

Exploring the limits of DNA size: naphtho-homologated DNA bases and pairs.

A new four-base genetic helix, yDNA, composed of widened benzopyrimidine-purine pairs.

Novel benzopyrimidines as widened analogues of DNA bases.

Benzotrithiole 2-oxide: a new family of thiol-activated DNA-cleaving functionalities.

Acid-promoted DNA-cleaving activities and total synthesis of varacin C.