Detalhe da pesquisa
1.
Atomic structure of T6SS reveals interlaced array essential to function.
Cell
; 160(5): 940-951, 2015 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25723168
2.
Output-driven feedback system control platform optimizes combinatorial therapy of tuberculosis using a macrophage cell culture model.
Proc Natl Acad Sci U S A
; 113(15): E2172-9, 2016 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27035987
3.
Massively parallel delivery of large cargo into mammalian cells with light pulses.
Nat Methods
; 12(5): 439-44, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25849636
4.
A Pathogen-Specific Cargo Delivery Platform Based on Mesoporous Silica Nanoparticles.
J Am Chem Soc
; 139(19): 6663-6668, 2017 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28437093
5.
Redox-Triggered Release of Moxifloxacin from Mesoporous Silica Nanoparticles Functionalized with Disulfide Snap-Tops Enhances Efficacy Against Pneumonic Tularemia in Mice.
Small
; 12(27): 3690-702, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27246117
6.
pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice.
Small
; 11(38): 5066-78, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26193431
7.
Tuberculosis: pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice (Small 38/2015).
Small
; 11(38): 5065, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26450161
8.
Efficacy and safety of an innovative short-course regimen containing clofazimine for treatment of drug-susceptible tuberculosis: a clinical trial.
Emerg Microbes Infect
; 12(1): 2187247, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36872899
9.
O-antigen-deficient Francisella tularensis Live Vaccine Strain mutants are ingested via an aberrant form of looping phagocytosis and show altered kinetics of intracellular trafficking in human macrophages.
Infect Immun
; 80(3): 952-67, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22202123
10.
Targeted intracellular delivery of antituberculosis drugs to Mycobacterium tuberculosis-infected macrophages via functionalized mesoporous silica nanoparticles.
Antimicrob Agents Chemother
; 56(5): 2535-45, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22354311
11.
The Mycobacterium bovis bacille Calmette-Guerin phagosome proteome.
Mol Cell Proteomics
; 9(1): 32-53, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19815536
12.
Atomic Structure of IglD Demonstrates Its Role as a Component of the Baseplate Complex of the Francisella Type VI Secretion System.
mBio
; 13(5): e0127722, 2022 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36036641
13.
A Francisella tularensis live vaccine strain (LVS) mutant with a deletion in capB, encoding a putative capsular biosynthesis protein, is significantly more attenuated than LVS yet induces potent protective immunity in mice against F. tularensis challenge.
Infect Immun
; 78(10): 4341-55, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20643859
14.
Francisella tularensis phagosomal escape does not require acidification of the phagosome.
Infect Immun
; 77(5): 1757-73, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19237528
15.
The metabolic activity of Mycobacterium tuberculosis, assessed by use of a novel inducible GFP expression system, correlates with its capacity to inhibit phagosomal maturation and acidification in human macrophages.
Mol Microbiol
; 68(4): 1047-60, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18363792
16.
Atomic Structure of the Francisella T6SS Central Spike Reveals a Unique α-Helical Lid and a Putative Cargo.
Structure
; 27(12): 1811-1819.e6, 2019 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31677891
17.
Nanoparticle Formulation of Moxifloxacin and Intramuscular Route of Delivery Improve Antibiotic Pharmacokinetics and Treatment of Pneumonic Tularemia in a Mouse Model.
ACS Infect Dis
; 5(2): 281-291, 2019 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30480992
18.
Artificial intelligence enabled parabolic response surface platform identifies ultra-rapid near-universal TB drug treatment regimens comprising approved drugs.
PLoS One
; 14(5): e0215607, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31075149
19.
Intracellular Photothermal Delivery for Suspension Cells Using Sharp Nanoscale Tips in Microwells.
ACS Nano
; 13(9): 10835-10844, 2019 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31487464
20.
The Francisella Type VI Secretion System.
Front Cell Infect Microbiol
; 8: 121, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29740542