Detalhe da pesquisa
1.
In vitro and in vivo neuroprotective effect of novel mPGES-1 inhibitor in animal model of Parkinson's disease.
Bioorg Med Chem Lett
; 74: 128920, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35931244
2.
Nc886, a Novel Suppressor of the Type I Interferon Response Upon Pathogen Intrusion.
Int J Mol Sci
; 22(4)2021 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33670458
3.
Inhibitory effects of triarylpyrazole derivatives on LPS-induced nitric oxide and PGE2 productions in murine RAW 264.7 macrophages.
Bioorg Med Chem Lett
; 30(4): 126884, 2020 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31879211
4.
A novel mPGES-1 inhibitor alleviates inflammatory responses by downregulating PGE2 in experimental models.
Prostaglandins Other Lipid Mediat
; 144: 106347, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31229523
5.
EGFR inhibitors from cancer to inflammation: Discovery of 4-fluoro-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide as a novel anti-inflammatory EGFR inhibitor.
Bioorg Chem
; 86: 112-118, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30685642
6.
Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE2 in LPS-induced RAW 264.7 cells.
Bioorg Med Chem Lett
; 27(11): 2613-2616, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28408221
7.
p-Coumaroyl Anthocyanin Mixture Isolated from Tuber Epidermis of Solanum tuberosum Attenuates Reactive Oxygen Species and Pro-inflammatory Mediators by Suppressing NF-κB and STAT1/3 Signaling in LPS-Induced RAW264.7 Macrophages.
Biol Pharm Bull
; 40(11): 1894-1902, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29093336
8.
α-Solanine Isolated From Solanum Tuberosum L. cv Jayoung Abrogates LPS-Induced Inflammatory Responses Via NF-κB Inactivation in RAW 264.7 Macrophages and Endotoxin-Induced Shock Model in Mice.
J Cell Biochem
; 117(10): 2327-39, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26931732
9.
Hit-to-lead optimization of phenylsulfonyl hydrazides for a potent suppressor of PGE2 production: Synthesis, biological activity, and molecular docking study.
Bioorg Med Chem Lett
; 26(1): 94-9, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26602278
10.
Synthesis, structure determination, and biological evaluation of phenylsulfonyl hydrazide derivatives as potential anti-inflammatory agents.
Bioorg Med Chem Lett
; 26(21): 5193-5197, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27720548
11.
Biflorin, Isolated from the Flower Buds of Syzygium aromaticum L., Suppresses LPS-Induced Inflammatory Mediators via STAT1 Inactivation in Macrophages and Protects Mice from Endotoxin Shock.
J Nat Prod
; 79(4): 711-20, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26977531
12.
Fulgidic Acid Isolated from the Rhizomes of Cyperus rotundus Suppresses LPS-Induced iNOS, COX-2, TNF-α, and IL-6 Expression by AP-1 Inactivation in RAW264.7 Macrophages.
Biol Pharm Bull
; 38(7): 1081-6, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26133719
13.
Synthesis and PGE2 production inhibition of s-triazine derivatives as a novel scaffold in RAW 264.7 macrophage cells.
Bioorg Med Chem Lett
; 24(23): 5418-22, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453800
14.
3',4'-Dihydroxyflavone mitigates inflammatory responses by inhibiting LPS and TLR4/MD2 interaction.
Phytomedicine
; 109: 154553, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36610153
15.
Early stage ultraviolet irradiation damage to skin collagen can be suppressed by HPA axis control via controlled CYP11B.
Biomed Pharmacother
; 155: 113716, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36162374
16.
Mosloflavone-Resveratrol Hybrid TMS-HDMF-5z Exhibits Potent In Vitro and In Vivo Anti-Inflammatory Effects Through NF-κB, AP-1, and JAK/STAT Inactivation.
Front Pharmacol
; 13: 857789, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35529447
17.
A host non-coding RNA, nc886, plays a pro-viral role by promoting virus trafficking to the nucleus.
Mol Ther Oncolytics
; 24: 683-694, 2022 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35284627
18.
Regulation of ROS-Dependent JNK Pathway by 2'-Hydroxycinnamaldehyde Inducing Apoptosis in Human Promyelocytic HL-60 Leukemia Cells.
Pharmaceutics
; 13(11)2021 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34834209
19.
Improved tumor-suppressive effect of OZ-001 combined with cisplatin mediated by mTOR/p70S6K and STAT3 inactivation in A549 human lung cancer cells.
Biomed Pharmacother
; 142: 111961, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34329824
20.
Standardized hot water extract from the leaves of Hydrangea serrata (Thunb.) Ser. alleviates obesity via the AMPK pathway and modulation of the gut microbiota composition in high fat diet-induced obese mice.
Food Funct
; 12(6): 2672-2685, 2021 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33656018