Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Non-viral precision T cell receptor replacement for personalized cell therapy.

Foy, Susan P; Jacoby, Kyle; Bota, Daniela A; Hunter, Theresa; Pan, Zheng; Stawiski, Eric; Ma, Yan; Lu, William; Peng, Songming; Wang, Clifford L; Yuen, Benjamin; Dalmas, Olivier; Heeringa, Katharine; Sennino, Barbara; Conroy, Andy; Bethune, Michael T; Mende, Ines; White, William; Kukreja, Monica; Gunturu, Swetha; Humphrey, Emily; Hussaini, Adeel; An, Duo; Litterman, Adam J; Quach, Boi Bryant; Ng, Alphonsus H C; Lu, Yue; Smith, Chad; Campbell, Katie M; Anaya, Daniel; Skrdlant, Lindsey; Huang, Eva Yi-Hsuan; Mendoza, Ventura; Mathur, Jyoti; Dengler, Luke; Purandare, Bhamini; Moot, Robert; Yi, Michael C; Funke, Roel; Sibley, Alison; Stallings-Schmitt, Todd; Oh, David Y; Chmielowski, Bartosz; Abedi, Mehrdad; Yuan, Yuan; Sosman, Jeffrey A; Lee, Sylvia M; Schoenfeld, Adam J; Baltimore, David; Heath, James R.

Nature ; 615(7953): 687-696, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36356599

2.

Associating sleep problems with advanced cancer diagnosis, and immune checkpoint treatment outcomes: a pilot study.

Sillah, Arthur; Peters, Ulrike; Watson, Nathaniel F; Tykodi, Scott S; Hall, Evan T; Silverman, Allison; Malen, Rachel C; Thompson, John A; Lee, Sylvia M; Bhatia, Shailender; Veatch, Joshua; Warner, Jeannie; Thornton, Timothy; Phipps, Amanda I.

Support Care Cancer ; 30(5): 3829-3838, 2022 May.

Artigo em Inglês | MEDLINE | ID: mdl-35034197

3.

Predictive lifestyle markers for efficacy of cancer immune checkpoint inhibitors: a commentary.

Sillah, Arthur; Tykodi, Scott S; Hall, Evan T; Thompson, John A; Watson, Nathaniel F; Lee, Sylvia M; Bhatia, Shailender; Veatch, Joshua; Warner, Jeannie; Peters, Ulrike; Malen, Rachel C; Silverman, Allison; Phipps, Amanda I.

Future Oncol ; 17(4): 363-369, 2021 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-33397134

4.

Immunotherapy Approaches Beyond PD-1 Inhibition: the Future of Cellular Therapy for Head and Neck Squamous Cell Carcinoma.

Qureshi, Hannan A; Lee, Sylvia M.

Curr Treat Options Oncol ; 20(4): 31, 2019 03 14.

Artigo em Inglês | MEDLINE | ID: mdl-30874960

5.

Phase 2 study of RO4929097, a gamma-secretase inhibitor, in metastatic melanoma: SWOG 0933.

Lee, Sylvia M; Moon, James; Redman, Bruce G; Chidiac, Tarek; Flaherty, Lawrence E; Zha, Yuanyuan; Othus, Megan; Ribas, Antoni; Sondak, Vernon K; Gajewski, Thomas F; Margolin, Kim A.

Cancer ; 121(3): 432-440, 2015 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-25250858

6.

Systemic therapy of metastatic melanoma: on the road to cure.

Bhatia, Shailender; Tykodi, Scott S; Lee, Sylvia M; Thompson, John A.

Oncology (Williston Park) ; 29(2): 126-35, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25683834

7.

Lifileucel, an Autologous Tumor-infiltrating Lymphocyte Monotherapy, in Patients with Advanced Non-small Cell Lung Cancer Resistant to Immune Checkpoint Inhibitors.

Schoenfeld, Adam J; Lee, Sylvia M; Doger de Speville, Bernard; Gettinger, Scott N; Hafliger, Simon; Sukari, Ammar; Papa, Sophie; Rodriguez-Moreno, Juan Francisco; Graf Finckenstein, Friedrich; Fiaz, Rana; Catlett, Melissa; Chen, Guang; Qi, Rongsu; Masteller, Emma L; Gontcharova, Viktoria; He, Kai.

Cancer Discov ; 2024 Apr 02.

Artigo em Inglês | MEDLINE | ID: mdl-38563600

8.

Impact of HPV status on immune responses in head and neck squamous cell carcinoma.

Qureshi, Hannan A; Zhu, Xiaodong; Yang, Grace H; Steadele, Melissa; Pierce, Robert H; Futran, Neal D; Lee, Sylvia M; Méndez, Eduardo; Houghton, A McGarry.

Oral Oncol ; 127: 105774, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35219073

9.

Neoantigen-specific CD4⁺ T cells in human melanoma have diverse differentiation states and correlate with CD8⁺ T cell, macrophage, and B cell function.

Veatch, Joshua R; Lee, Sylvia M; Shasha, Carolyn; Singhi, Naina; Szeto, Julia L; Moshiri, Ata S; Kim, Teresa S; Smythe, Kimberly; Kong, Paul; Fitzgibbon, Matthew; Jesernig, Brenda; Bhatia, Shailender; Tykodi, Scott S; Hall, Evan T; Byrd, David R; Thompson, John A; Pillarisetty, Venu G; Duhen, Thomas; McGarry Houghton, A; Newell, Evan; Gottardo, Raphael; Riddell, Stanley R.

Cancer Cell ; 40(4): 393-409.e9, 2022 04 11.

Artigo em Inglês | MEDLINE | ID: mdl-35413271

10.

Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade.

Srivastava, Shivani; Furlan, Scott N; Jaeger-Ruckstuhl, Carla A; Sarvothama, Megha; Berger, Carolina; Smythe, Kimberly S; Garrison, Sarah M; Specht, Jennifer M; Lee, Sylvia M; Amezquita, Robert A; Voillet, Valentin; Muhunthan, Vishaka; Yechan-Gunja, Sushma; Pillai, Smitha P S; Rader, Christoph; Houghton, A McGarry; Pierce, Robert H; Gottardo, Raphael; Maloney, David G; Riddell, Stanley R.

Cancer Cell ; 39(2): 193-208.e10, 2021 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-33357452

11.

A Phase II Trial of Pembrolizumab and Vorinostat in Recurrent Metastatic Head and Neck Squamous Cell Carcinomas and Salivary Gland Cancer.

Rodriguez, Cristina P; Wu, Qian Vicky; Voutsinas, Jenna; Fromm, Jonathan R; Jiang, Xiuyun; Pillarisetty, Venu G; Lee, Sylvia M; Santana-Davila, Rafael; Goulart, Bernardo; Baik, Christina S; Chow, Laura Q M; Eaton, Keith; Martins, Renato.

Clin Cancer Res ; 26(4): 837-845, 2020 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-31796519

12.

Endogenous CD4⁺ T Cells Recognize Neoantigens in Lung Cancer Patients, Including Recurrent Oncogenic KRAS and ERBB2 (Her2) Driver Mutations.

Veatch, Joshua R; Jesernig, Brenda L; Kargl, Julia; Fitzgibbon, Matthew; Lee, Sylvia M; Baik, Christina; Martins, Renato; Houghton, A McGarry; Riddell, Stanley R.

Cancer Immunol Res ; 7(6): 910-922, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-31043415

13.

Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma.

Veatch, Joshua R; Lee, Sylvia M; Fitzgibbon, Matthew; Chow, I-Ting; Jesernig, Brenda; Schmitt, Tom; Kong, Ying Ying; Kargl, Julia; Houghton, A McGarry; Thompson, John A; McIntosh, Martin; Kwok, William W; Riddell, Stanley R.

J Clin Invest ; 128(4): 1563-1568, 2018 04 02.

Artigo em Inglês | MEDLINE | ID: mdl-29360643

14.

Phase I Trial of ALT-803, A Novel Recombinant IL15 Complex, in Patients with Advanced Solid Tumors.

Margolin, Kim; Morishima, Chihiro; Velcheti, Vamsidhar; Miller, Jeffrey S; Lee, Sylvia M; Silk, Ann W; Holtan, Shernan G; Lacroix, Andreanne M; Fling, Steven P; Kaiser, Judith C; Egan, Jack O; Jones, Monica; Rhode, Peter R; Rock, Amy D; Cheever, Martin A; Wong, Hing C; Ernstoff, Marc S.

Clin Cancer Res ; 24(22): 5552-5561, 2018 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-30045932

15.

Neutrophils dominate the immune cell composition in non-small cell lung cancer.

Kargl, Julia; Busch, Stephanie E; Yang, Grace H Y; Kim, Kyoung-Hee; Hanke, Mark L; Metz, Heather E; Hubbard, Jesse J; Lee, Sylvia M; Madtes, David K; McIntosh, Martin W; Houghton, A McGarry.

Nat Commun ; 8: 14381, 2017 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-28146145

16.

Combined IL-21-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient.

Chapuis, Aude G; Lee, Sylvia M; Thompson, John A; Roberts, Ilana M; Margolin, Kim A; Bhatia, Shailender; Sloan, Heather L; Lai, Ivy; Wagener, Felecia; Shibuya, Kendall; Cao, Jianhong; Wolchok, Jedd D; Greenberg, Philip D; Yee, Cassian.

J Exp Med ; 213(7): 1133-9, 2016 06 27.

Artigo em Inglês | MEDLINE | ID: mdl-27242164

17.

T-Cell Therapy Using Interleukin-21-Primed Cytotoxic T-Cell Lymphocytes Combined With Cytotoxic T-Cell Lymphocyte Antigen-4 Blockade Results in Long-Term Cell Persistence and Durable Tumor Regression.

Chapuis, Aude G; Roberts, Ilana M; Thompson, John A; Margolin, Kim A; Bhatia, Shailender; Lee, Sylvia M; Sloan, Heather L; Lai, Ivy P; Farrar, Erik A; Wagener, Felecia; Shibuya, Kendall C; Cao, Jianhong; Wolchok, Jedd D; Greenberg, Philip D; Yee, Cassian.

J Clin Oncol ; 34(31): 3787-3795, 2016 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-27269940

18.

Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8(+) T cells.

Pollack, Seth M; Jones, Robin L; Farrar, Erik A; Lai, Ivy P; Lee, Sylvia M; Cao, Jianhong; Pillarisetty, Venu G; Hoch, Benjamin L; Gullett, Ashley; Bleakley, Marie; Conrad, Ernest U; Eary, Janet F; Shibuya, Kendall C; Warren, Edus H; Carstens, Jason N; Heimfeld, Shelly; Riddell, Stanley R; Yee, Cassian.

J Immunother Cancer ; 2(1): 36, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-25317334

19.

Another LAP in the race.

Lee, Sylvia M; Yee, Cassian.

Cancer Discov ; 2(2): 107-9, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-22585852

20.

A new addition to the PD-1 checkpoint inhibitors for non-small cell lung cancer-the anti-PDL1 antibody-MEDI4736.

Lee, Sylvia M; Chow, Laura Q.

Transl Lung Cancer Res ; 3(6): 408-10, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25806336

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