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1.
BMC Pediatr ; 24(1): 94, 2024 Feb 02.
Artigo em Inglês | MEDLINE | ID: mdl-38308216

RESUMO

BACKGROUND: Headaches are the most common neurologic symptoms in the pediatric population. Most primary headache in children and adolescents focuses on associated factors, including noise. Auditory discomfort is related to recognizing the pain. We aimed to analyze the headache profile of pediatric populations and the connection between noise exposure and head pain in children and adolescents. METHODS: We reviewed retrospectively medical records of the pediatric population with headaches in Gyeongsang National University Changwon Hospital from January 2022 to April 2023. Personal headache profiling from self-questionnaires and environmental noise data from the National Noise Information System (NNIS) were used to analyze each variable, and chi-square tests and linear regression models by SAS were used to analyze the statistical correlation. RESULTS: Of the 224 participants, 125 were clinically diagnosed with headaches. Of the 104 pubertal subjects, 56.7% were diagnosed with headaches, compared to 60% in the prepubertal group. Both daytime and nighttime noise was significantly higher in the diagnosed headache group than in the non-diagnosed group. Headache duration increased by daytime and nighttime noise with statistical significance in age-adjusted models. CONCLUSION: We found that noise exposure is correlated to headaches in children and adolescents. Daytime and nighttime environmental noise exposure was significantly associated with the duration of headaches through our data. Therefore, we assume that noise exposure is vitally relevant to prolonged headaches in the pediatric population. Further research is needed to improve our data.


Assuntos
Cefaleia , Dor , Adolescente , Humanos , Criança , Estudos Retrospectivos , Cefaleia/etiologia , Inquéritos e Questionários
2.
Int Ophthalmol ; 44(1): 6, 2024 Feb 05.
Artigo em Inglês | MEDLINE | ID: mdl-38316664

RESUMO

PURPOSE: Recent studies examining the neuroprotective effects of metformin on open-angle glaucoma (OAG) have failed to provide consistent results. In this study, we investigated the association between metformin use and OAG. METHODS: Data were obtained from a sample cohort of the Korean National Health Insurance database. Patients diagnosed with type-2 diabetes (T2DM) between 2004 and 2013 were included. We performed propensity score-matched analysis in a matched cohort (N = 20,646). The risk of the newly developed OAG was estimated using a Cox proportional hazards model. Including the present study, the meta-analysis included five studies to calculate the pooled risk for OAG based on metformin use. RESULTS: In the adjusted model, the analysis revealed no statistical association between metformin use and OAG incidence (hazard ratio [HR] 1.05; 95% confidence interval [CI] 0.79-1.40; P = 0.738). The highest tercile of metformin use demonstrated no statistical significance (HR 0.93 [95% CI 0.63-1.37]; P = 0.703). No significant dose-dependent association was observed between the cumulative dose and incidence of OAG (P-value for trend = 0.336). In a meta-analysis of four published articles and the present study, the common-effects and random-effects models indicated conflicting results in terms of significance. The random effects model demonstrated no significant association (pooled risk ratio 0.53; 95% CI 0.24-1.19; P = 0.123). CONCLUSION: We found no significant association between metformin use and OAG incidence in patients with T2DM in this population-based cohort study and meta-analysis. Further studies are needed to investigate the association between metformin use and the risk of OAG among patients with T2DM.


Assuntos
Diabetes Mellitus Tipo 2 , Glaucoma de Ângulo Aberto , Metformina , Humanos , Glaucoma de Ângulo Aberto/diagnóstico , Estudos de Coortes , Metformina/efeitos adversos , Fatores de Risco , Estudos Retrospectivos , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/tratamento farmacológico , Diabetes Mellitus Tipo 2/epidemiologia , Incidência
3.
Ecotoxicol Environ Saf ; 263: 115334, 2023 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-37567098

RESUMO

The etiology of autoimmune disease pathogeneses remains obscure, and the impact of general environmental or occupational exposure to external airborne agents (EAA) on autoimmune diseases remains understudied. This study was conducted to elucidate the association between exposure to EAA and the risk of autoimmune diseases according to exposure type. From the NHIS-NSC (2002-2019), 17,984,963 person-years were included in the data analysis. Autoimmune diseases were categorized based on the InterLymph classification. We estimated the incidence and rate ratio of autoimmune diseases according to the EAA exposure. Association between exposure and autoimmune diseases was investigated using logistic regression analysis, adjusted for potential confounders. Of the 1,082,879 participants, 86,376 (8.0%) were diagnosed with autoimmune diseases. Among these, 208 (14.1%) experienced severe exposure to EAA. Total EAA exposure was significantly associated with any autoimmune disease (OR: 1.29, 95% CI: 1.11-1.49) and organ-specific diseases (OR: 1.28, 95% CI: 1.08-1.53). Inorganic dust exposure was associated with organ-specific diseases (OR, 1.38; 95% CI: 1.01-1.81). Exposure to other dust was significantly associated with any autoimmune disease (OR: 1.35, 95% CI: 1.10-1.66), connective tissue diseases (OR: 1.43, 95% CI: 1.03-1.99), and organ-specific diseases (OR: 1.28, 95% CI: 1.00-1.65). Exposure to EAA was predominantly related to psoriasis, rheumatoid arthritis (RA), and type 1 diabetes (T1DM). We found that exposure to EAA is a potential risk factor for autoimmune diseases, especially psoriasis, RA, and T1DM. Our findings provide insight into the role of exposure to severe airborne agents in the pathogenesis of autoimmune diseases.


Assuntos
Artrite Reumatoide , Doenças Autoimunes , Diabetes Mellitus Tipo 1 , Psoríase , Humanos , Doenças Autoimunes/epidemiologia , Doenças Autoimunes/complicações , Artrite Reumatoide/epidemiologia , Artrite Reumatoide/etiologia , Poeira
4.
Ecotoxicol Environ Saf ; 268: 115677, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37979362

RESUMO

BACKGROUND: Noise is defined as unwanted sound. It may induce negative emotions and mental health problems and may even lead to increased suicide risk. However, the impact of noise exposure on environmental diseases and disease severity is not well understood. This study aimed to elucidate the association between night-time noise exposure and the prevalence of environmental diseases in South Korea. METHODS: We conducted an analysis of the Environmental Disease Database provide by the National Health Insurance Service (NHIS) from 2013 to 2017. After spatially interpolating the noise data provided by the National Noise Information System (NNIS), night-time noise values in the district level were obtained by calculating the mean noise values at the administrative district level. The linear regression analyses were performed to test the association between the age-standardized prevalence ratio (SPR) and the night-time noise exposure in the district level. RESULTS: In areas with high night-time noise exposure (≥55 dB), the SPR for atopic dermatitis and allergic rhinitis were 1.0515 (95 % confidence interval [CI]:1.0508-1.0521) and 1.0202 (95 % CI:1.0201-1.0204), respectively, which were higher than those in the general population. The SPR for environmental diseases, including atopic dermatitis, asthma, and allergic rhinitis, was 1.0104 (95 % CI:1.0103-1.0105). Additionally, a significant linear association was observed between the level of nocturnal noise exposure and the total hospitalization period for atopic dermatitis (ß = 399.3, p < 0.01). CONCLUSION: We provide evidence of a significant association between night-time environmental noise and environmental diseases, particularly atopic dermatitis and allergic rhinitis. Furthermore, we observed a significant linear association between night-time noise exposure and the severity of atopic dermatitis.


Assuntos
Asma , Dermatite Atópica , Rinite Alérgica , Humanos , Dermatite Atópica/epidemiologia , Dermatite Atópica/etiologia , Fatores de Risco , Asma/epidemiologia , Asma/etiologia , Rinite Alérgica/epidemiologia , Rinite Alérgica/etiologia , Suscetibilidade a Doenças
5.
BMC Womens Health ; 22(1): 265, 2022 06 29.
Artigo em Inglês | MEDLINE | ID: mdl-35768813

RESUMO

BACKGROUND: Premenstrual syndrome (PMS) is the most common disease of the genitourinary tract in women. Although a sizeable proportion of women have symptoms or diagnosed PMS, its etiology remains unclear. The purpose of this cohort is to offer incidence and relevant risk factors of PMS among reproductive-aged Korean female workers. METHODS: Cohort data used were from the National Health Insurance Service-Female Employees (from 2007 to 2015) conducted by the NHIS. A total of 121,024 female workers were analyzed to estimate the incidence and hazard ratio of PMS. PMS data was based on information obtained from medical facility visits during an eight-year follow-up. RESULTS: The incidence of PMS was 7.0% during follow-up periods. In industrial classification, human health and social work activities have the highest incidence (9.0%) of PMS. Cumulative incidence of PMS has continuously increased by approximately 1% annually for eight years. Adjusted hazard ratio with 95% confidence interval was significantly higher in the 15-19 years old age group (2.81, 95%CI 2.35-3.36), manual worker (1.06, 95%CI 1.01-1.12), with anemia (1.13, 95%CI 1.06-1.20), and underweight (1.21, 95%CI 1.10-1.25) compared to those in the reference group. CONCLUSION: This study describes the PMS status with trend and risk factors using follow-up design among women under a middle-aged working population. Further study is warranted for better understanding on the risk factors of PMS for reproductive-aged female workers.


Assuntos
Síndrome Pré-Menstrual , Adolescente , Adulto , Feminino , Humanos , Incidência , Pessoa de Meia-Idade , Síndrome Pré-Menstrual/epidemiologia , Estudos Prospectivos , República da Coreia/epidemiologia , Fatores de Risco , Adulto Jovem
6.
J Korean Med Sci ; 36(17): e119, 2021 May 03.
Artigo em Inglês | MEDLINE | ID: mdl-33942580

RESUMO

BACKGROUND: This study investigates the safety and health status of geographically isolated and confined workers. METHODS: This study was conducted in Baekryeong Island in Korea in 2020. The age-standardized prevalence ratios (aSPR) for occupational injury, unmet medical needs, psychological status, and lifestyle were estimated from the available data. Also, we compared the aSPRs of workers in Baekryeong Island with a reference study population who participated in a nationally representative survey in Korea. RESULTS: The study revealed that Baekryeong Island workers had an increased risk of acquiring health and safety problems compared to the general worker population. The island workers showed a significant increase in unmet medical care (aSPR, 5.319; 95% confidence interval [CI], 3.984-6.958) and occupational injury (aSPR, 8.371; 95% CI, 3.820-15.892). CONCLUSION: This study identified the safety and health problems of geographically isolated workers in Baekryeong Island. The risk of occupational injury and unmet medical care are simultaneously highlighted in the region's population, thereby underscoring the importance of prevention.


Assuntos
Emprego/estatística & dados numéricos , Nível de Saúde , Estilo de Vida , Saúde Ocupacional/estatística & dados numéricos , Traumatismos Ocupacionais/epidemiologia , Isolamento Social/psicologia , Adulto , Feminino , Necessidades e Demandas de Serviços de Saúde , Humanos , Ilhas , Masculino , Pessoa de Meia-Idade , Prevalência , República da Coreia/epidemiologia , Fatores Socioeconômicos
7.
Public Health Nutr ; 23(18): 3356-3367, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32183914

RESUMO

OBJECTIVE: Adequate energy and nutrient intakes are important for workers who spend at least one-third of their day working. We investigated differences in these intakes among Korean workers because few studies have reported on energy or nutrient intakes, related to working conditions (long working hours, shift work and non-standard work). DESIGN: Dietary intake was assessed using 1-d 24-h recall. Energy and nutrient intakes were evaluated using age- and sex-specific dietary reference intakes for Korean citizens. Occupational characteristics were obtained from self-reported Korean National Health and Nutritional Examination Survey (KNHANES) data (occupational classification, working hours, shift work and non-standard workers). An age, education and household income-adjusted logistic regression model was applied to investigate differences in inappropriate energy and nutrient intakes, by sex and occupation. SETTING: Cross-sectional study. PARTICIPANTS: From KNHANES (2007-2016), 11 145 participants (5401 males; 5744 females) were included, finally. RESULTS: Males with long working hours had higher inappropriate carbohydrate, protein, water, vitamin B2 and phosphate intakes than those who worked ≤60 h/week. Long working hours among females were significantly associated with total energy and nutrient 'under-intake'. Male shift and non-standard workers had higher inappropriate protein, water, mineral and vitamin intakes. Multivariate logistic regression revealed that white- and male pink-collar workers had significantly increased risks of water and vitamins A, C, B1 and niacin 'under-intake'. CONCLUSIONS: We found different rates of inappropriate energy and micronutrient intakes according to working conditions. Younger workers with long hours and shift work schedules were vulnerable to inappropriate energy and nutrient intakes.


Assuntos
Dieta , Ingestão de Energia , Carga de Trabalho , Adulto , Estudos Transversais , Ingestão de Alimentos , Feminino , Humanos , Masculino , Micronutrientes , Estado Nutricional , República da Coreia , Vitaminas
8.
BMC Public Health ; 20(1): 768, 2020 May 24.
Artigo em Inglês | MEDLINE | ID: mdl-32448255

RESUMO

BACKGROUND: Although numerous studies on occupational post-traumatic stress disorder (PTSD) have been conducted prior to the 1950-2010 seminal systematic review by Skogstad et al., the prevalence, risk factors, and impact of this disorder following traumatic events in occupational settings remain unclear. This study aims to address this knowledge gap by reviewing the literature published after 2010. METHODS: We reviewed literature from databases such as PubMed and Google Scholar using PRISMA guidelines to identify studies that address occupational PTSD and examined the status (prevalence or incidence), the risk factors, and the health effects of PTSD among workers. RESULTS: In total, 123 articles were identified, and finally, 31 (25.2%) articles were selected after excluding duplicates. Various occupational traumatic physical events were reported such as natural or manmade disaster, explosion, accident, handling refugee corpses, or bullying at work. Risk of PTSD was closely associated with working conditions, severity of injury, history of mental disorder, occurrence of psychiatric symptoms at the time of the event, personality, interpersonal relationships, etc. Workers with PTSD were likely to experience a deterioration of physical and psychological health and impairment of social and occupational functioning. CONCLUSIONS: Our review suggests that many workers remain highly vulnerable to occupational PTSD and its consequences.


Assuntos
Estresse Ocupacional/epidemiologia , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Adulto , Desastres , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores de Risco
9.
Toxicol Ind Health ; 36(12): 971-978, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33107405

RESUMO

Occupation-related dust exposure is common, especially with increased industrialization. While occupational dust-related health issues caused by inhalation or ingestion have been well studied, only a few studies have examined the dermatologic effects of occupational dust exposure. This study aimed to investigate the association between occupational dust exposure and dermatologic symptoms in Korean workers. Among the large-scale representative data from the fifth Korean Working Conditions Survey, 45,700 workers were selected for study. Occupational dust exposure level was categorized as none, moderate, and severe, and dermatologic symptoms were assessed using a questionnaire on health problems. We analyzed the association between occupational dust exposure and dermatologic symptoms using multivariate logistic regression. Risks of skin problems and work-related skin problems were significantly associated with the level of occupational dust exposure in a dose-dependent manner (odds ratio (95% confidence interval): moderate, 1.51 (1.14-2.01); severe, 2.39 (1.74-3.29) in general skin problems; moderate, 1.72 (1.22-2.42); severe, 3.06 (2.11-4.44) in work-related skin problems). We, thus, demonstrate an association between occupational dust exposure and skin problems. As skin absorption of dust is a major route of dust exposure at the workplace, it is necessary to determine the efficacy of continuous management of occupational dust exposure.


Assuntos
Poluentes Ocupacionais do Ar/análise , Poeira/análise , Doenças Profissionais/epidemiologia , Exposição Ocupacional/análise , Dermatopatias/epidemiologia , Adulto , Relação Dose-Resposta a Droga , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Saúde Ocupacional , República da Coreia/epidemiologia , Índice de Gravidade de Doença , Local de Trabalho
10.
BMC Public Health ; 19(1): 1679, 2019 Dec 16.
Artigo em Inglês | MEDLINE | ID: mdl-31842839

RESUMO

It was highlighted that the original article [1] contained a mismatch between the result section of the abstract and Table 2. This Correction article shows the incorrect and correct result section of this article's Abstract.

11.
BMC Public Health ; 19(1): 1339, 2019 Oct 22.
Artigo em Inglês | MEDLINE | ID: mdl-31640649

RESUMO

BACKGROUND: The association between spontaneous abortion (SA) and occupational characteristics among working women is not well-studied. This study aimed to assess the risk of SA and occupational factors such as occupational classification, working hours, and work schedules among working Korean women aged > 19 years. METHODS: In this cross-sectional study, 4078 working women were identified from among 25,534 workers in the Korea National Health and Nutrition Examination Surveys V (2010-2012) database, to obtain data on SA history and the number of SAs. Odds ratios (ORs) and 95% confidence intervals (CIs) for SA were calculated using multiple logistic regression models after adjusting for age, education, household income, cigarette smoking, alcohol consumption, and obesity status. The weighted prevalence for the number of SAs was calculated according to occupational characteristics to demonstrate the SA status among working Korean women. RESULTS: SA occurrence was reported in 5.7% of the study participants. The ORs (95% CIs) for SA were significantly higher in pink-, green-, and blue-collared workers than in white-collared workers. Regarding weekly working hours, compared with ≤50 h spent working, the ORs (95% CIs) for 51-60, 61-70, and > 70 h per week were 1.26 (0.87-1.84), 1.63 (1.04-2.56), and 1.73 (1.10-2.70), respectively. A significantly higher weighted prevalence of repeat SAs was observed in pink- and green-collared workers and in those who worked long hours. CONCLUSION: We found a significant association between SA, repeat SA, and occupational characteristics among working Korean women.


Assuntos
Aborto Espontâneo/epidemiologia , Doenças Profissionais/epidemiologia , Mulheres Trabalhadoras/estatística & dados numéricos , Trabalho/estatística & dados numéricos , Adulto , Estudos Transversais , Feminino , Humanos , Pessoa de Meia-Idade , Inquéritos Nutricionais , Gravidez , Prevalência , República da Coreia/epidemiologia , Fatores de Risco , Adulto Jovem
12.
J Korean Med Sci ; 34(48): e313, 2019 Dec 16.
Artigo em Inglês | MEDLINE | ID: mdl-31833267

RESUMO

BACKGROUND: Mental health problems are a growing issue among customer-facing workers. This study aimed to investigate the workers' symptoms of anxiety, depression, and sleep disturbance caused by customer complaints and the suppression of one's emotions at work. METHODS: This study used the data from the fifth Korean Working Conditions Survey 2017 database. The subjects comprised 23,128 workers (men, 11,007; women, 12,121). The odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multiple logistic regression models, to determine the effect of the exposure level of engaging with angry clients and suppressing one's emotions at work on mental health. RESULTS: Among the workers engaging with angry customers, compared to the "Rarely" group as a reference point, the "Always" group showed elevated OR values (at [95% CI]) of 1.52 (1.10-2.10), 1.86 (1.05-3.27), 4.43 (3.11-6.33), 3.74 (2.51-5.55), 3.89 (2.65-5.70) for men workers; and 2.86 (1.94-4.22), 2.55 (1.73-3.75), 3.75 (2.82-4.98), 3.81 (2.84-5.09), 3.84 (2.88-5.12) for women workers, for depression, anxiety, difficulty falling asleep, waking up during sleep, and extreme fatigue after waking up, respectively. For suppressing one's emotions at work, the OR values of the "Always" group were 2.32 (1.53-3.51), 2.46 (1.73-3.50), 2.54 (1.88-3.43), 2.64 (1.92-3.64), 2.42 (1.81-3.24) for men workers; and 2.23 (1.53-3.25), 2.31 (1.61-3.33), 2.26 (1.72-2.96), 1.53 (1.19-1.97), 2.15 (1.62-2.85) for women workers, for depression, anxiety, and difficulty falling asleep, waking up during sleep, and extreme fatigue after waking up, respectively. CONCLUSION: The emotional labor demanded from customer-facing workers, incurred by facing customer complaints and suppressing one's emotions at work, was found to be significantly associated with the development of depression, anxiety, and sleep disturbance symptoms among the Korean working population.


Assuntos
Ansiedade/diagnóstico , Depressão/diagnóstico , Transtornos do Sono-Vigília/diagnóstico , Adulto , Ansiedade/epidemiologia , Bases de Dados Factuais , Depressão/epidemiologia , Emoções , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Razão de Chances , República da Coreia/epidemiologia , Transtornos do Sono-Vigília/epidemiologia , Inquéritos e Questionários , Local de Trabalho
13.
J Nerv Ment Dis ; 205(9): 699-704, 2017 09.
Artigo em Inglês | MEDLINE | ID: mdl-28092293

RESUMO

The exact nature of pain (amount or severity) associated with in depression in the elderly population has not been studied extensively yet. We investigated the association between the characteristics of pain and both symptomatic and diagnostic depression using data from the 2012 Korean Longitudinal Study of Aging (2164 men, 2066 women). Symptomatic depression was identified a score of 12 or higher on the 10-item Center for Epidemiologic Studies-Depression Scale. Odds ratios with a 95% confidence interval was calculated for depression using multiple logistic regression models after adjusting for age, sex, socioeconomic status, health behavioral factors, and chronic diseases. The fully adjusted odds ratio (95% confidence interval) for symptomatic/diagnostic depression were "1" = 2.09 (1.62-2.49)/1.71 (1.03-2.86), "2" = 1.88 (1.42-2.49)/1.82 (1.05-3.13), and ">3" = 2.27 (1.71-3.01)/3.21 (1.94-5.32), and 1.86 (1.48-2.33)/1.57 (1.00-2.49) for mild, 1.74 (1.22-2.48)/2.10 (1.11-3.98) for moderate, and 5.41 (3.77-7.77)/7.34 (4.15-12.99) for severe of pain. The results indicated a significant association between the number of sites and severity of pain and the prevalence of depression in the Korean elderly.


Assuntos
Envelhecimento/fisiologia , Depressão/epidemiologia , Dor/epidemiologia , Idoso , Idoso de 80 Anos ou mais , Comorbidade , Feminino , Humanos , Estudos Longitudinais , Masculino , Prevalência , República da Coreia/epidemiologia , Índice de Gravidade de Doença
14.
BMC Public Health ; 17(1): 579, 2017 06 15.
Artigo em Inglês | MEDLINE | ID: mdl-28619107

RESUMO

BACKGROUND: Suicide is a serious public health concern worldwide, and the fourth leading cause of death in Korea. Few studies have focused on risk factors for suicide attempt among people with suicidal ideation. The aim of the present study was to investigate the risk factors and develop prediction models for suicide attempt among people with suicidal ideation in the Korean population. METHOD: This study included 1567 men and 3726 women aged 20 years and older who had suicidal ideation from the Korea National Health and Nutrition Examination Survey from 2007 to 2012. Among them, 106 men and 188 women attempted suicide. Multivariate logistic regression analysis with backward stepwise elimination was performed to find risk factors for suicide attempt. Sub-group analysis, dividing participants into under 50 and at least 50 years old was also performed. RESULTS: Among people with suicidal ideation, age, education, cancer, and depressive disorder were selected as risk factors for suicide attempt in men. Age, education, national basic livelihood security, daily activity limitation, depressive disorder, stress, smoking, and regular exercise were selected in women. Area under curves of our prediction models in men and women were 0.728 and 0.716, respectively. CONCLUSIONS: It is important to pay attention to populations with suicidal ideation and the risk factors mentioned above. Prediction models using the determined risk factors could be useful to detect high-risk groups early for suicide attempt among people with suicidal ideation. It is necessary to develop specific action plans for these high-risk groups to prevent suicide.


Assuntos
Ideação Suicida , Tentativa de Suicídio/estatística & dados numéricos , Atividades Cotidianas , Adulto , Distribuição por Idade , Idoso , Estudos Transversais , Transtorno Depressivo/epidemiologia , Exercício Físico , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Inquéritos Nutricionais , República da Coreia/epidemiologia , Fatores de Risco , Fumar/epidemiologia , Fatores Socioeconômicos , Estresse Psicológico/epidemiologia
15.
BMC Musculoskelet Disord ; 18(1): 236, 2017 05 31.
Artigo em Inglês | MEDLINE | ID: mdl-28566092

RESUMO

BACKGROUND: Snoring is frequently associated with obstructive sleep apnea (OSA). Previous studies have shown that bone mineral density was significantly lower in patients with OSA than in controls; however, these studies did not focus on fractures. Fragility fractures can lead to long-term disabilities and a decrease in quality of life. The present study aimed to investigate the association between snoring and fragility fractures. METHODS: This study included 2969 men and 3220 women aged 40 years and older from the Ansung and Ansan cohort studies in Korea. During a 10-year follow-up period, 129 and 273 fracture cases were reported in men and women, respectively. RESULTS: Severe snoring (6-7 nights per week or sleep disturbance by snoring in the next room) was a statistically significant risk factor for fracture (p = 0.006, hazard ratio 1.68, 95% confidence interval 1.16-2.43) after adjusting for covariates related to fragility fracture in women. However, both snoring and severe snoring groups did not show significant associations with the fracture risk in men. CONCLUSIONS: Thus, information on the frequency of snoring in women may improve the accuracy of fragility fracture risk prediction, which can help in deciding whether intervention or treatment is necessary.


Assuntos
Fraturas Ósseas/epidemiologia , Fragilidade/epidemiologia , Vigilância da População , Caracteres Sexuais , Ronco/epidemiologia , Adulto , Densidade Óssea/fisiologia , Estudos de Coortes , Feminino , Seguimentos , Fraturas Ósseas/diagnóstico , Fragilidade/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Vigilância da População/métodos , Estudos Prospectivos , República da Coreia/epidemiologia , Fatores de Risco , Ronco/diagnóstico , Inquéritos e Questionários , Fatores de Tempo
16.
J Korean Med Sci ; 32(4): 568-575, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28244280

RESUMO

Unintentional environmental exposure to toxicants is associated with an aggravated health status of the general population. Involuntary smoking (IS) exposure is one of the main routes to involuntary toxicants exposure. However, few studies have attempted to understand the environmental cadmium exposure by IS exposure in the general, non-smoking population. The purpose of the current study was to examine the relationship between blood cadmium level and IS level according to gender and age. We used the Korea National Health and Nutrition Examination Survey (KNHANES) IV-VI data that included heavy metal and urine cotinine sampling with IS exposure history. The final analysis comprised 3,493 adults (1,231 males and 2,262 females) and 395 adolescents (210 males and 185 females). Linear regression was performed to estimate the association between self-reported IS exposure with urine cotinine level and blood cadmium level in non-smokers with gender and age group stratification. In final regression model, the effect values (B) (standard errors [SE]) between blood cadmium and urine cotinine level in men was 0.0004 (0.0001) and 0.0006 (0.0002) in adults and adolescents, the B (SE) in women was 0.0006 (0.0002) and 0.0016 (0.0006) in adults and adolescents. Our study revealed, for the first time, a significant association between blood cadmium and IS exposure in non-smokers. Greater efforts are needed to improve environmental justices of the general population from IS, considering the severe harmful effects of involuntary exposure to even a low level of cadmium.


Assuntos
Cádmio/sangue , Cotinina/urina , Fumar , Poluição por Fumaça de Tabaco/análise , Adolescente , Adulto , Estudos Transversais , Feminino , Humanos , Modelos Lineares , Masculino , Inquéritos Nutricionais , Autorrelato
17.
Occup Environ Med ; 73(11): 794-801, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27621410

RESUMO

Crystalline silica is a widely used industrial material that is readily available worldwide, and is one of the most common types of particulate mineral pollutants. It has been classified as a group 1 human carcinogen of the respiratory system; however, whether it is linked to gastric cancer remains uncertain. We conducted a systemic review and meta-analyses to search for evidence of the relationship between gastric cancer and occupational exposure to crystalline silica. We searched for articles on occupations involving silica exposure and gastric cancer studies up to December 2014. Pooled-risk estimates of the association between occupational crystalline silica exposure and risk of gastric cancer were calculated by a random effects model. Metaregression analyses of industry type and histological confirmation status, study design and industrial subgroup analyses were performed. 29 articles, including 9 case-control and 20 cohort studies, were analysed. The overall summary effects size was 1.25 (95% CI 1.18 to 1.34) for the association of occupational silica exposure with gastric cancer. Both heterogeneity and publication bias were partially attenuated after subgroup analyses. Heterogeneity of studies was attenuated after metaregression by industry. Higher overall effects were observed in the mining and foundry industries. We found a significant relationship between occupational crystalline silica exposure and gastric cancer. Our results were strengthened by various subgroup analyses and, considering the biological plausibility of our premise, further studies are required to better understand this association.


Assuntos
Poluentes Ocupacionais do Ar/efeitos adversos , Poluição do Ar/efeitos adversos , Doenças Profissionais/induzido quimicamente , Exposição Ocupacional/efeitos adversos , Dióxido de Silício/efeitos adversos , Neoplasias Gástricas/induzido quimicamente , Carcinógenos , Humanos , Indústrias , Mineração , Doenças Profissionais/epidemiologia , Análise de Regressão , Fatores de Risco , Neoplasias Gástricas/epidemiologia
18.
Am J Hum Biol ; 28(5): 729-35, 2016 09 10.
Artigo em Inglês | MEDLINE | ID: mdl-27121332

RESUMO

OBJECTIVES: Low-level lead exposure has been associated with increases in blood pressure (BP) and impairment of the cardiovascular system. Prehypertension is not categorized as a disease currently; however, individuals with untreated prehypertension are known to be at increased risk of progression to hypertension and mortality caused by cardiovascular disease. We investigated the association between blood lead levels below the threshold for the harmful effects of lead and the prevalence of prehypertension in Korean adults. METHODS: A total of 8,493 participants (3,945 men and 4,548 women) were included in the current analysis, using data from the fourth, fifth, and sixth Korean National Health and Nutrition Examination Survey (KNHANES) in 2007-2013. Blood analysis, self-report questionnaires, and physical examinations were used to assess blood lead levels, BP, and medical history. Odds ratios (OR) and 95% confidence intervals (95% CI) for prehypertension were calculated using multiple logistic regression models. RESULTS: Compared to the first quartile (Q1) blood lead level (0.206-1.539 µg/dl), the ORs (95% CI) were 1.24 (1.04-1.48) in Q2, (1.540-2.056 µg/dl), 1.27 (1.06-1.52) in Q3, (2.057-2.716 µg/dl), and 1.30 (1.07-1.60) in Q4 (2.717-24.532 µg/dl) for the prevalence of prehypertension after adjusting for age, sex, morbidity status, socioeconomic status, and health behavioral variables. CONCLUSIONS: Our large, cross-sectional, nationwide study revealed that blood lead levels below the threshold for the harmful effects of lead were significantly associated with prehypertension. Am. J. Hum. Biol. 28:729-735, 2016. © 2016 Wiley Periodicals, Inc.


Assuntos
Exposição Ambiental , Poluentes Ambientais/sangue , Chumbo/sangue , Pré-Hipertensão/epidemiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos Nutricionais , Pré-Hipertensão/induzido quimicamente , Prevalência , República da Coreia/epidemiologia , Adulto Jovem
19.
Am J Ind Med ; 59(8): 685-94, 2016 08.
Artigo em Inglês | MEDLINE | ID: mdl-27345305

RESUMO

BACKGROUND: Occupation influences the risk for developing chronic metabolic diseases. METHODS: We compared the prevalence of MetS by International Standard Classification of Occupations using the nationally representative data in Korea (KNHANES). We enrolled 16,763 workers (9,175 males; 7,588 females) who had measurements for the National Cholesterol Education Program criteria III and other variables. OR and 95%CIs for MetS and its components were estimated according to occupation using the multiple logistic regression models. RESULTS: The occupational groups with the highest age-standardized prevalence of MetS were lower skilled white-collar men (31.1 ± 2.4%) and green-collar women (24.2 ± 2.9%). Compared with the unskilled male blue-collar group, which had the lowest prevalence of MetS, the OR (95%CIs) of MetS in men were 1.77 (1.45-2.15) in higher skilled white-collar, 1.82 (1.47-2.26) in lower-skilled white-collar, 1.63 (1.32-2.01) in pink-collar and 1.37 (1.13-1.66) in skilled blue-collar workers in final logistic regression model. CONCLUSIONS: MetS and its components vary by occupational category and gender in ways that may guide health interventions. Am. J. Ind. Med. 59:685-694, 2016. © 2016 Wiley Periodicals, Inc.


Assuntos
Síndrome Metabólica/epidemiologia , Doenças Profissionais/epidemiologia , Ocupações/classificação , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , República da Coreia/epidemiologia , Fatores de Risco
20.
Tohoku J Exp Med ; 238(1): 25-32, 2016 01.
Artigo em Inglês | MEDLINE | ID: mdl-26666368

RESUMO

Concealing emotions at work can cause considerable psychological stress. While there is extensive research on the adverse health effects of concealing emotions and the association between allergic diseases and stress, research has not yet investigated whether concealing emotions at work is associated with allergic rhinitis. Allergic rhinitis is a common disease in many industrialized countries, and its prevalence is increasing. Thus, our aim was to determine the strength of this association using data from three years (2007-2009) of the 4th Korean National Health and Nutrition Examination Survey. Participants (aged 20-64) were 8,345 individuals who were economically active and who had completed the questionnaire items on concealing emotions at work. Odds ratio (OR) and 95% confidence intervals (95% CIs) were calculated for allergic rhinitis using logistic regression models. Among all participants, 3,140 subjects (37.6%) reported concealing their emotions at work: 1,661 men and 1,479 women. The OR (95% CIs) for allergic rhinitis among those who concealed emotions at work versus those who did not was 1.318 (1.148-1.512). Stratified by sex, the OR (95% CIs) was 1.307 (1.078-1.585) among men and 1.346 (1.105-1.639) among women. Thus, individuals who concealed their emotions at work were significantly more likely to have a diagnosis of AR in comparison to those who did not. Because concealing emotions at work has adverse health effects, labor policies that aim to reduce this practice are needed.


Assuntos
Emoções , Rinite Alérgica/epidemiologia , Rinite Alérgica/psicologia , Trabalho/psicologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , República da Coreia/epidemiologia , Adulto Jovem
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