Detalhe da pesquisa
1.
Mass Spectrometry and Machine Learning Reveal Determinants of Client Recognition by Antiamyloid Chaperones.
Mol Cell Proteomics
; 21(10): 100413, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36115577
2.
Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain.
Nano Lett
; 23(12): 5836-5841, 2023 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37084706
3.
Monitoring Disassembly and Cargo Release of Phase-Separated Peptide Coacervates with Native Mass Spectrometry.
Anal Chem
; 95(29): 10869-10872, 2023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37439740
4.
Spider Silk Protein Forms Amyloid-Like Nanofibrils through a Non-Nucleation-Dependent Polymerization Mechanism.
Small
; 19(46): e2304031, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37455347
5.
Smallest Secondary Nucleation Competent Aß Aggregates Probed by an ATP-Independent Molecular Chaperone Domain.
Biochemistry
; 60(9): 678-688, 2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33621049
6.
Maresin 1 attenuates pro-inflammatory activation induced by ß-amyloid and stimulates its uptake.
J Cell Mol Med
; 25(1): 434-447, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33225628
7.
Blood-brain and blood-cerebrospinal fluid passage of BRICHOS domains from two molecular chaperones in mice.
J Biol Chem
; 294(8): 2606-2615, 2019 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30598503
8.
Dissociation of a BRICHOS trimer into monomers leads to increased inhibitory effect on Aß42 fibril formation.
Biochim Biophys Acta
; 1854(8): 835-43, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25891900
9.
Molecular basis for different substrate-binding sites and chaperone functions of the BRICHOS domain.
Protein Sci
; 33(7): e5063, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38864729
10.
Advances in mass spectrometry to unravel the structure and function of protein condensates.
Nat Protoc
; 18(12): 3653-3661, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37907762
11.
A new kid in the folding funnel: Molecular chaperone activities of the BRICHOS domain.
Protein Sci
; 32(6): e4645, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37096906
12.
The heat shock protein LarA activates the Lon protease in response to proteotoxic stress.
Nat Commun
; 14(1): 7636, 2023 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37993443
13.
Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation.
Commun Biol
; 6(1): 497, 2023 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156997
14.
A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1.
PNAS Nexus
; 2(2): pgac303, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36743470
15.
ATP-independent molecular chaperone activity generated under reducing conditions.
Protein Sci
; 31(8): e4378, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35900025
16.
Abilities of the BRICHOS domain to prevent neurotoxicity and fibril formation are dependent on a highly conserved Asp residue.
RSC Chem Biol
; 3(11): 1342-1358, 2022 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36349220
17.
Ion mobility-mass spectrometry shows stepwise protein unfolding under alkaline conditions.
Chem Commun (Camb)
; 57(12): 1450-1453, 2021 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33439171
18.
Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry.
JACS Au
; 1(12): 2385-2393, 2021 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34977906
19.
Recombinant Bri3 BRICHOS domain is a molecular chaperone with effect against amyloid formation and non-fibrillar protein aggregation.
Sci Rep
; 10(1): 9817, 2020 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32555390
20.
Augmentation of Bri2 molecular chaperone activity against amyloid-ß reduces neurotoxicity in mouse hippocampus in vitro.
Commun Biol
; 3(1): 32, 2020 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31959875