Detalhe da pesquisa
1.
The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα.
Nature
; 541(7638): 541-545, 2017 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28068668
2.
Activation of IGF1R/p110ß/AKT/mTOR confers resistance to α-specific PI3K inhibition.
Breast Cancer Res
; 18(1): 41, 2016 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27048245
3.
Anticipating mechanisms of resistance to PI3K inhibition in breast cancer: a challenge in the era of precision medicine.
Biochem Soc Trans
; 42(4): 733-41, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25109950
4.
Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells.
Blood
; 118(8): 2211-21, 2011 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21730355
5.
N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer.
Cell Rep Med
; 4(4): 101002, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37044095
6.
Inhibition of DDR1-BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer.
EMBO Mol Med
; 10(4)2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29438985
7.
YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells.
Am J Cancer Res
; 5(6): 1972-87, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269757
8.
SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2.
Nat Commun
; 5: 3159, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24457997
9.
Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells.
Cancer Res
; 69(6): 2279-86, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19276381
10.
Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression.
Cancer Res
; 68(23): 9809-16, 2008 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19047160
11.
D-myo-inositol 1-phosphate as a surrogate of D-myo-inositol 1,4,5-tris phosphate to monitor G protein-coupled receptor activation.
Anal Biochem
; 358(1): 126-35, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16965760